node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AEE49049.1 | AEE50262.1 | Halhy_1151 | Halhy_2387 | KEGG: phe:Phep_3324 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504770512. | COGs: COG1181 D-alanine-D-alanine ligase and related ATP-grasp protein; InterPro IPR005543:IPR011127; KEGG: chu:CHU_0924 D-alanine--D-alanine ligase A; PFAM: D-alanine--D-alanine ligase, N-terminal; PASTA; SMART: PASTA; SPTR: D-alanine--D-alanine ligase A; IMG reference gene:2504771755; PFAM: D-ala D-ala ligase N-terminus; PASTA domain. | 0.804 |
AEE49049.1 | AEE51818.1 | Halhy_1151 | Halhy_3970 | KEGG: phe:Phep_3324 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504770512. | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | 0.841 |
AEE49049.1 | ddl | Halhy_1151 | Halhy_2716 | KEGG: phe:Phep_3324 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504770512. | D-alanine--D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | 0.676 |
AEE49049.1 | ftsA | Halhy_1151 | Halhy_1150 | KEGG: phe:Phep_3324 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504770512. | Cell division protein FtsA; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family. | 0.965 |
AEE49049.1 | murA | Halhy_1151 | Halhy_2629 | KEGG: phe:Phep_3324 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504770512. | UDP-N-acetylglucosamine1- carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | 0.484 |
AEE49049.1 | murC | Halhy_1151 | Halhy_1152 | KEGG: phe:Phep_3324 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504770512. | UDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.971 |
AEE49049.1 | murD | Halhy_1151 | Halhy_1155 | KEGG: phe:Phep_3324 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504770512. | UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.921 |
AEE49049.1 | murE | Halhy_1151 | Halhy_1157 | KEGG: phe:Phep_3324 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504770512. | UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-d iaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.676 |
AEE49049.1 | murF | Halhy_1151 | Halhy_4800 | KEGG: phe:Phep_3324 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504770512. | UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diamin opimelate/D-alanyl-D-alanyl ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.698 |
AEE49049.1 | murG | Halhy_1151 | Halhy_1153 | KEGG: phe:Phep_3324 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504770512. | Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.905 |
AEE50262.1 | AEE49049.1 | Halhy_2387 | Halhy_1151 | COGs: COG1181 D-alanine-D-alanine ligase and related ATP-grasp protein; InterPro IPR005543:IPR011127; KEGG: chu:CHU_0924 D-alanine--D-alanine ligase A; PFAM: D-alanine--D-alanine ligase, N-terminal; PASTA; SMART: PASTA; SPTR: D-alanine--D-alanine ligase A; IMG reference gene:2504771755; PFAM: D-ala D-ala ligase N-terminus; PASTA domain. | KEGG: phe:Phep_3324 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504770512. | 0.804 |
AEE50262.1 | AEE51818.1 | Halhy_2387 | Halhy_3970 | COGs: COG1181 D-alanine-D-alanine ligase and related ATP-grasp protein; InterPro IPR005543:IPR011127; KEGG: chu:CHU_0924 D-alanine--D-alanine ligase A; PFAM: D-alanine--D-alanine ligase, N-terminal; PASTA; SMART: PASTA; SPTR: D-alanine--D-alanine ligase A; IMG reference gene:2504771755; PFAM: D-ala D-ala ligase N-terminus; PASTA domain. | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | 0.971 |
AEE50262.1 | ddl | Halhy_2387 | Halhy_2716 | COGs: COG1181 D-alanine-D-alanine ligase and related ATP-grasp protein; InterPro IPR005543:IPR011127; KEGG: chu:CHU_0924 D-alanine--D-alanine ligase A; PFAM: D-alanine--D-alanine ligase, N-terminal; PASTA; SMART: PASTA; SPTR: D-alanine--D-alanine ligase A; IMG reference gene:2504771755; PFAM: D-ala D-ala ligase N-terminus; PASTA domain. | D-alanine--D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | 0.912 |
AEE50262.1 | ftsA | Halhy_2387 | Halhy_1150 | COGs: COG1181 D-alanine-D-alanine ligase and related ATP-grasp protein; InterPro IPR005543:IPR011127; KEGG: chu:CHU_0924 D-alanine--D-alanine ligase A; PFAM: D-alanine--D-alanine ligase, N-terminal; PASTA; SMART: PASTA; SPTR: D-alanine--D-alanine ligase A; IMG reference gene:2504771755; PFAM: D-ala D-ala ligase N-terminus; PASTA domain. | Cell division protein FtsA; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family. | 0.781 |
AEE50262.1 | murA | Halhy_2387 | Halhy_2629 | COGs: COG1181 D-alanine-D-alanine ligase and related ATP-grasp protein; InterPro IPR005543:IPR011127; KEGG: chu:CHU_0924 D-alanine--D-alanine ligase A; PFAM: D-alanine--D-alanine ligase, N-terminal; PASTA; SMART: PASTA; SPTR: D-alanine--D-alanine ligase A; IMG reference gene:2504771755; PFAM: D-ala D-ala ligase N-terminus; PASTA domain. | UDP-N-acetylglucosamine1- carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | 0.420 |
AEE50262.1 | murC | Halhy_2387 | Halhy_1152 | COGs: COG1181 D-alanine-D-alanine ligase and related ATP-grasp protein; InterPro IPR005543:IPR011127; KEGG: chu:CHU_0924 D-alanine--D-alanine ligase A; PFAM: D-alanine--D-alanine ligase, N-terminal; PASTA; SMART: PASTA; SPTR: D-alanine--D-alanine ligase A; IMG reference gene:2504771755; PFAM: D-ala D-ala ligase N-terminus; PASTA domain. | UDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.744 |
AEE50262.1 | murD | Halhy_2387 | Halhy_1155 | COGs: COG1181 D-alanine-D-alanine ligase and related ATP-grasp protein; InterPro IPR005543:IPR011127; KEGG: chu:CHU_0924 D-alanine--D-alanine ligase A; PFAM: D-alanine--D-alanine ligase, N-terminal; PASTA; SMART: PASTA; SPTR: D-alanine--D-alanine ligase A; IMG reference gene:2504771755; PFAM: D-ala D-ala ligase N-terminus; PASTA domain. | UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.661 |
AEE50262.1 | murE | Halhy_2387 | Halhy_1157 | COGs: COG1181 D-alanine-D-alanine ligase and related ATP-grasp protein; InterPro IPR005543:IPR011127; KEGG: chu:CHU_0924 D-alanine--D-alanine ligase A; PFAM: D-alanine--D-alanine ligase, N-terminal; PASTA; SMART: PASTA; SPTR: D-alanine--D-alanine ligase A; IMG reference gene:2504771755; PFAM: D-ala D-ala ligase N-terminus; PASTA domain. | UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-d iaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.617 |
AEE50262.1 | murF | Halhy_2387 | Halhy_4800 | COGs: COG1181 D-alanine-D-alanine ligase and related ATP-grasp protein; InterPro IPR005543:IPR011127; KEGG: chu:CHU_0924 D-alanine--D-alanine ligase A; PFAM: D-alanine--D-alanine ligase, N-terminal; PASTA; SMART: PASTA; SPTR: D-alanine--D-alanine ligase A; IMG reference gene:2504771755; PFAM: D-ala D-ala ligase N-terminus; PASTA domain. | UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diamin opimelate/D-alanyl-D-alanyl ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.962 |
AEE50262.1 | murG | Halhy_2387 | Halhy_1153 | COGs: COG1181 D-alanine-D-alanine ligase and related ATP-grasp protein; InterPro IPR005543:IPR011127; KEGG: chu:CHU_0924 D-alanine--D-alanine ligase A; PFAM: D-alanine--D-alanine ligase, N-terminal; PASTA; SMART: PASTA; SPTR: D-alanine--D-alanine ligase A; IMG reference gene:2504771755; PFAM: D-ala D-ala ligase N-terminus; PASTA domain. | Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.689 |