| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AEE48682.1 | AEE50677.1 | Halhy_0775 | Halhy_2811 | Butyrate--CoA ligase; COGs: COG0365 Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase; InterPro IPR000873; KEGG: afu:AF1287 acetyl-CoA synthetase (acs-6); PFAM: AMP-dependent synthetase/ligase; PRIAM: Butyrate--CoA ligase; SPTR: Acetyl-CoA synthetase (Acs-6); IMG reference gene:2504770134; PFAM: AMP-binding enzyme. | GCN5-related N-acetyltransferase; COGs: COG1042 Acyl-CoA synthetase (NDP forming); InterPro IPR003781:IPR013650:IPR000182; KEGG: deh:cbdb_A1077 acetyl-CoA synthetase; PFAM: GCN5-related N-acetyltransferase; ATP-grasp fold, succinyl-CoA synthetase-type; CoA-binding; SPTR: Acetyltransferase, GNAT family; IMG reference gene:2504772183; PFAM: Acetyltransferase (GNAT) family. | 0.445 |
| AEE48682.1 | AEE51523.1 | Halhy_0775 | Halhy_3671 | Butyrate--CoA ligase; COGs: COG0365 Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase; InterPro IPR000873; KEGG: afu:AF1287 acetyl-CoA synthetase (acs-6); PFAM: AMP-dependent synthetase/ligase; PRIAM: Butyrate--CoA ligase; SPTR: Acetyl-CoA synthetase (Acs-6); IMG reference gene:2504770134; PFAM: AMP-binding enzyme. | 2-oxoacid:acceptor oxidoreductase, alpha subunit; COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterPro IPR019752:IPR002880; KEGG: gpb:HDN1F_09550 2-ketoglutarate: nadp oxidoreductase, alpha subunit; PFAM: Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal; Pyruvate/ketoisovalerate oxidoreductase; PRIAM: 2-oxoglutarate synthase; SPTR: 2-ketoglutarate: nadp oxidoreductase, alpha subunit; TIGRFAM: 2-oxoacid:acceptor oxidoreductase, alpha subunit; IMG reference gene:2504773052; PFAM: domain; Pyruvate ferredoxin/flav [...] | 0.402 |
| AEE48682.1 | AEE54329.1 | Halhy_0775 | Halhy_6513 | Butyrate--CoA ligase; COGs: COG0365 Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase; InterPro IPR000873; KEGG: afu:AF1287 acetyl-CoA synthetase (acs-6); PFAM: AMP-dependent synthetase/ligase; PRIAM: Butyrate--CoA ligase; SPTR: Acetyl-CoA synthetase (Acs-6); IMG reference gene:2504770134; PFAM: AMP-binding enzyme. | COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterProIPR011895:IPR002880:IPR019752:IPR019456:IPR 001450:IPR011766; KEGG: mca:MCA0769 pyruvate ferredoxin/flavodoxin oxidoreductase family protein; PFAM: Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal; Pyruvate/ketoisovalerate oxidoreductase; Pyruvate-flavodoxin oxidoreductase, EKR domain; 4Fe-4S ferredoxin, iron-sulphur binding, subgroup; Thiamine pyrophosphate enzyme, C-terminal TPP-binding; PRIAM: Pyruvate dehydrogenase (NADP(+)); SPTR: Pyruvate ferredoxin/fla [...] | 0.587 |
| AEE50675.1 | AEE50677.1 | Halhy_2809 | Halhy_2811 | KEGG: pdi:BDI_2505 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504772181. | GCN5-related N-acetyltransferase; COGs: COG1042 Acyl-CoA synthetase (NDP forming); InterPro IPR003781:IPR013650:IPR000182; KEGG: deh:cbdb_A1077 acetyl-CoA synthetase; PFAM: GCN5-related N-acetyltransferase; ATP-grasp fold, succinyl-CoA synthetase-type; CoA-binding; SPTR: Acetyltransferase, GNAT family; IMG reference gene:2504772183; PFAM: Acetyltransferase (GNAT) family. | 0.568 |
| AEE50675.1 | pfkA-2 | Halhy_2809 | Halhy_2810 | KEGG: pdi:BDI_2505 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504772181. | 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. | 0.598 |
| AEE50677.1 | AEE48682.1 | Halhy_2811 | Halhy_0775 | GCN5-related N-acetyltransferase; COGs: COG1042 Acyl-CoA synthetase (NDP forming); InterPro IPR003781:IPR013650:IPR000182; KEGG: deh:cbdb_A1077 acetyl-CoA synthetase; PFAM: GCN5-related N-acetyltransferase; ATP-grasp fold, succinyl-CoA synthetase-type; CoA-binding; SPTR: Acetyltransferase, GNAT family; IMG reference gene:2504772183; PFAM: Acetyltransferase (GNAT) family. | Butyrate--CoA ligase; COGs: COG0365 Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase; InterPro IPR000873; KEGG: afu:AF1287 acetyl-CoA synthetase (acs-6); PFAM: AMP-dependent synthetase/ligase; PRIAM: Butyrate--CoA ligase; SPTR: Acetyl-CoA synthetase (Acs-6); IMG reference gene:2504770134; PFAM: AMP-binding enzyme. | 0.445 |
| AEE50677.1 | AEE50675.1 | Halhy_2811 | Halhy_2809 | GCN5-related N-acetyltransferase; COGs: COG1042 Acyl-CoA synthetase (NDP forming); InterPro IPR003781:IPR013650:IPR000182; KEGG: deh:cbdb_A1077 acetyl-CoA synthetase; PFAM: GCN5-related N-acetyltransferase; ATP-grasp fold, succinyl-CoA synthetase-type; CoA-binding; SPTR: Acetyltransferase, GNAT family; IMG reference gene:2504772183; PFAM: Acetyltransferase (GNAT) family. | KEGG: pdi:BDI_2505 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504772181. | 0.568 |
| AEE50677.1 | AEE50780.1 | Halhy_2811 | Halhy_2916 | GCN5-related N-acetyltransferase; COGs: COG1042 Acyl-CoA synthetase (NDP forming); InterPro IPR003781:IPR013650:IPR000182; KEGG: deh:cbdb_A1077 acetyl-CoA synthetase; PFAM: GCN5-related N-acetyltransferase; ATP-grasp fold, succinyl-CoA synthetase-type; CoA-binding; SPTR: Acetyltransferase, GNAT family; IMG reference gene:2504772183; PFAM: Acetyltransferase (GNAT) family. | COGs: COG0123 Deacetylase including yeast histone deacetylase and acetoin utilization protein; InterPro IPR000286; KEGG: mev:Metev_1525 histone deacetylase superfamily; PFAM: Histone deacetylase superfamily; SPTR: Histone deacetylase superfamily; IMG reference gene:2504772290; PFAM: Histone deacetylase domain. | 0.585 |
| AEE50677.1 | AEE51523.1 | Halhy_2811 | Halhy_3671 | GCN5-related N-acetyltransferase; COGs: COG1042 Acyl-CoA synthetase (NDP forming); InterPro IPR003781:IPR013650:IPR000182; KEGG: deh:cbdb_A1077 acetyl-CoA synthetase; PFAM: GCN5-related N-acetyltransferase; ATP-grasp fold, succinyl-CoA synthetase-type; CoA-binding; SPTR: Acetyltransferase, GNAT family; IMG reference gene:2504772183; PFAM: Acetyltransferase (GNAT) family. | 2-oxoacid:acceptor oxidoreductase, alpha subunit; COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterPro IPR019752:IPR002880; KEGG: gpb:HDN1F_09550 2-ketoglutarate: nadp oxidoreductase, alpha subunit; PFAM: Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal; Pyruvate/ketoisovalerate oxidoreductase; PRIAM: 2-oxoglutarate synthase; SPTR: 2-ketoglutarate: nadp oxidoreductase, alpha subunit; TIGRFAM: 2-oxoacid:acceptor oxidoreductase, alpha subunit; IMG reference gene:2504773052; PFAM: domain; Pyruvate ferredoxin/flav [...] | 0.588 |
| AEE50677.1 | AEE52007.1 | Halhy_2811 | Halhy_4161 | GCN5-related N-acetyltransferase; COGs: COG1042 Acyl-CoA synthetase (NDP forming); InterPro IPR003781:IPR013650:IPR000182; KEGG: deh:cbdb_A1077 acetyl-CoA synthetase; PFAM: GCN5-related N-acetyltransferase; ATP-grasp fold, succinyl-CoA synthetase-type; CoA-binding; SPTR: Acetyltransferase, GNAT family; IMG reference gene:2504772183; PFAM: Acetyltransferase (GNAT) family. | acetoacetyl-CoA synthase; COGs: COG0365 Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase; InterPro IPR000873:IPR005914; KEGG: bts:Btus_1007 acetoacetyl-CoA synthase; PFAM: AMP-dependent synthetase/ligase; PRIAM: Acetoacetate--CoA ligase; SPTR: Acetoacetyl-CoA synthase; TIGRFAM: Acetoacetyl-CoA synthase; IMG reference gene:2504773547; PFAM: Domain of unknown function (DUF3448); AMP-binding enzyme; TIGRFAM: acetoacetyl-CoA synthase. | 0.534 |
| AEE50677.1 | AEE52198.1 | Halhy_2811 | Halhy_4354 | GCN5-related N-acetyltransferase; COGs: COG1042 Acyl-CoA synthetase (NDP forming); InterPro IPR003781:IPR013650:IPR000182; KEGG: deh:cbdb_A1077 acetyl-CoA synthetase; PFAM: GCN5-related N-acetyltransferase; ATP-grasp fold, succinyl-CoA synthetase-type; CoA-binding; SPTR: Acetyltransferase, GNAT family; IMG reference gene:2504772183; PFAM: Acetyltransferase (GNAT) family. | Transcriptional regulator, DeoR family; COGs: COG1349 Transcriptional regulators of sugar metabolism; InterPro IPR001034:IPR014036; KEGG: cpi:Cpin_6809 transcriptional regulator, DeoR family; PFAM: HTH transcriptional regulator, DeoR; HTH transcriptional regulator, DeoR N-terminal; SMART: HTH transcriptional regulator, DeoR N-terminal; SPTR: Transcriptional regulator, DeoR family; IMG reference gene:2504773740; PFAM: Bacterial regulatory proteins, deoR family; DeoR-like helix-turn-helix domain. | 0.684 |
| AEE50677.1 | AEE53858.1 | Halhy_2811 | Halhy_6035 | GCN5-related N-acetyltransferase; COGs: COG1042 Acyl-CoA synthetase (NDP forming); InterPro IPR003781:IPR013650:IPR000182; KEGG: deh:cbdb_A1077 acetyl-CoA synthetase; PFAM: GCN5-related N-acetyltransferase; ATP-grasp fold, succinyl-CoA synthetase-type; CoA-binding; SPTR: Acetyltransferase, GNAT family; IMG reference gene:2504772183; PFAM: Acetyltransferase (GNAT) family. | acetate/CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | 0.505 |
| AEE50677.1 | AEE54329.1 | Halhy_2811 | Halhy_6513 | GCN5-related N-acetyltransferase; COGs: COG1042 Acyl-CoA synthetase (NDP forming); InterPro IPR003781:IPR013650:IPR000182; KEGG: deh:cbdb_A1077 acetyl-CoA synthetase; PFAM: GCN5-related N-acetyltransferase; ATP-grasp fold, succinyl-CoA synthetase-type; CoA-binding; SPTR: Acetyltransferase, GNAT family; IMG reference gene:2504772183; PFAM: Acetyltransferase (GNAT) family. | COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterProIPR011895:IPR002880:IPR019752:IPR019456:IPR 001450:IPR011766; KEGG: mca:MCA0769 pyruvate ferredoxin/flavodoxin oxidoreductase family protein; PFAM: Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal; Pyruvate/ketoisovalerate oxidoreductase; Pyruvate-flavodoxin oxidoreductase, EKR domain; 4Fe-4S ferredoxin, iron-sulphur binding, subgroup; Thiamine pyrophosphate enzyme, C-terminal TPP-binding; PRIAM: Pyruvate dehydrogenase (NADP(+)); SPTR: Pyruvate ferredoxin/fla [...] | 0.610 |
| AEE50677.1 | pfkA-2 | Halhy_2811 | Halhy_2810 | GCN5-related N-acetyltransferase; COGs: COG1042 Acyl-CoA synthetase (NDP forming); InterPro IPR003781:IPR013650:IPR000182; KEGG: deh:cbdb_A1077 acetyl-CoA synthetase; PFAM: GCN5-related N-acetyltransferase; ATP-grasp fold, succinyl-CoA synthetase-type; CoA-binding; SPTR: Acetyltransferase, GNAT family; IMG reference gene:2504772183; PFAM: Acetyltransferase (GNAT) family. | 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. | 0.761 |
| AEE50677.1 | rnc | Halhy_2811 | Halhy_2561 | GCN5-related N-acetyltransferase; COGs: COG1042 Acyl-CoA synthetase (NDP forming); InterPro IPR003781:IPR013650:IPR000182; KEGG: deh:cbdb_A1077 acetyl-CoA synthetase; PFAM: GCN5-related N-acetyltransferase; ATP-grasp fold, succinyl-CoA synthetase-type; CoA-binding; SPTR: Acetyltransferase, GNAT family; IMG reference gene:2504772183; PFAM: Acetyltransferase (GNAT) family. | Ribonuclease 3; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism. | 0.440 |
| AEE50780.1 | AEE50677.1 | Halhy_2916 | Halhy_2811 | COGs: COG0123 Deacetylase including yeast histone deacetylase and acetoin utilization protein; InterPro IPR000286; KEGG: mev:Metev_1525 histone deacetylase superfamily; PFAM: Histone deacetylase superfamily; SPTR: Histone deacetylase superfamily; IMG reference gene:2504772290; PFAM: Histone deacetylase domain. | GCN5-related N-acetyltransferase; COGs: COG1042 Acyl-CoA synthetase (NDP forming); InterPro IPR003781:IPR013650:IPR000182; KEGG: deh:cbdb_A1077 acetyl-CoA synthetase; PFAM: GCN5-related N-acetyltransferase; ATP-grasp fold, succinyl-CoA synthetase-type; CoA-binding; SPTR: Acetyltransferase, GNAT family; IMG reference gene:2504772183; PFAM: Acetyltransferase (GNAT) family. | 0.585 |
| AEE50780.1 | AEE53858.1 | Halhy_2916 | Halhy_6035 | COGs: COG0123 Deacetylase including yeast histone deacetylase and acetoin utilization protein; InterPro IPR000286; KEGG: mev:Metev_1525 histone deacetylase superfamily; PFAM: Histone deacetylase superfamily; SPTR: Histone deacetylase superfamily; IMG reference gene:2504772290; PFAM: Histone deacetylase domain. | acetate/CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | 0.432 |
| AEE51523.1 | AEE48682.1 | Halhy_3671 | Halhy_0775 | 2-oxoacid:acceptor oxidoreductase, alpha subunit; COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterPro IPR019752:IPR002880; KEGG: gpb:HDN1F_09550 2-ketoglutarate: nadp oxidoreductase, alpha subunit; PFAM: Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal; Pyruvate/ketoisovalerate oxidoreductase; PRIAM: 2-oxoglutarate synthase; SPTR: 2-ketoglutarate: nadp oxidoreductase, alpha subunit; TIGRFAM: 2-oxoacid:acceptor oxidoreductase, alpha subunit; IMG reference gene:2504773052; PFAM: domain; Pyruvate ferredoxin/flav [...] | Butyrate--CoA ligase; COGs: COG0365 Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase; InterPro IPR000873; KEGG: afu:AF1287 acetyl-CoA synthetase (acs-6); PFAM: AMP-dependent synthetase/ligase; PRIAM: Butyrate--CoA ligase; SPTR: Acetyl-CoA synthetase (Acs-6); IMG reference gene:2504770134; PFAM: AMP-binding enzyme. | 0.402 |
| AEE51523.1 | AEE50677.1 | Halhy_3671 | Halhy_2811 | 2-oxoacid:acceptor oxidoreductase, alpha subunit; COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterPro IPR019752:IPR002880; KEGG: gpb:HDN1F_09550 2-ketoglutarate: nadp oxidoreductase, alpha subunit; PFAM: Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal; Pyruvate/ketoisovalerate oxidoreductase; PRIAM: 2-oxoglutarate synthase; SPTR: 2-ketoglutarate: nadp oxidoreductase, alpha subunit; TIGRFAM: 2-oxoacid:acceptor oxidoreductase, alpha subunit; IMG reference gene:2504773052; PFAM: domain; Pyruvate ferredoxin/flav [...] | GCN5-related N-acetyltransferase; COGs: COG1042 Acyl-CoA synthetase (NDP forming); InterPro IPR003781:IPR013650:IPR000182; KEGG: deh:cbdb_A1077 acetyl-CoA synthetase; PFAM: GCN5-related N-acetyltransferase; ATP-grasp fold, succinyl-CoA synthetase-type; CoA-binding; SPTR: Acetyltransferase, GNAT family; IMG reference gene:2504772183; PFAM: Acetyltransferase (GNAT) family. | 0.588 |
| AEE51523.1 | AEE52007.1 | Halhy_3671 | Halhy_4161 | 2-oxoacid:acceptor oxidoreductase, alpha subunit; COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterPro IPR019752:IPR002880; KEGG: gpb:HDN1F_09550 2-ketoglutarate: nadp oxidoreductase, alpha subunit; PFAM: Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal; Pyruvate/ketoisovalerate oxidoreductase; PRIAM: 2-oxoglutarate synthase; SPTR: 2-ketoglutarate: nadp oxidoreductase, alpha subunit; TIGRFAM: 2-oxoacid:acceptor oxidoreductase, alpha subunit; IMG reference gene:2504773052; PFAM: domain; Pyruvate ferredoxin/flav [...] | acetoacetyl-CoA synthase; COGs: COG0365 Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase; InterPro IPR000873:IPR005914; KEGG: bts:Btus_1007 acetoacetyl-CoA synthase; PFAM: AMP-dependent synthetase/ligase; PRIAM: Acetoacetate--CoA ligase; SPTR: Acetoacetyl-CoA synthase; TIGRFAM: Acetoacetyl-CoA synthase; IMG reference gene:2504773547; PFAM: Domain of unknown function (DUF3448); AMP-binding enzyme; TIGRFAM: acetoacetyl-CoA synthase. | 0.402 |