Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AEE50688.1COGs: COG2865 transcriptional regulator protein; InterPro IPR007421; KEGG: ssm:Spirs_4290 putative transcriptional regulator; PFAM: ATPase associated with various cellular activities, AAA-4; SPTR: Putative transcriptional regulator; IMG reference gene:2504772195; PFAM: HTH domain; Divergent AAA domain. (443 aa)    
Predicted Functional Partners:
AEE52853.1
COGs: COG2865 transcriptional regulator protein; InterPro IPR007421; KEGG: cch:Cag_1101 putative transcriptional regulator; PFAM: ATPase associated with various cellular activities, AAA-4; SPTR: Putative transcriptional regulator; IMG reference gene:2504774421; PFAM: Divergent AAA domain.
  
  
 
0.929
AEE48061.1
COGs: COG2865 transcriptional regulator protein; InterPro IPR007421; KEGG: aca:ACP_2163 ATPase, AAA family; PFAM: ATPase associated with various cellular activities, AAA-4; SPTR: ATPase, AAA family; IMG reference gene:2504769500; PFAM: Divergent AAA domain.
  
  
 
0.928
recG
ATP-dependent DNA helicase RecG; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA); Belongs to the helicase family. RecG subfamily.
     
 0.901
AEE50027.1
ATPase; COGs: COG1373 ATPase (AAA+ superfamily); KEGG: dap:Dacet_1071 ATPase; SPTR: ATPase; IMG reference gene:2504771509.
  
     0.625
AEE53932.1
Protein of unknown function DUF1016; COGs: COG4804 conserved hypothetical protein; InterPro IPR009362; KEGG: gpb:HDN1F_15170 protein of unknown function DUF1016; PFAM: Protein of unknown function DUF1016; SPTR: Putative uncharacterized protein; IMG reference gene:2504775512; PFAM: Protein of unknown function (DUF1016).
 
     0.543
AEE50127.1
Protein of unknown function DUF1016; COGs: COG4804 conserved hypothetical protein; InterPro IPR009362; KEGG: nde:NIDE0138 hypothetical protein; PFAM: Protein of unknown function DUF1016; SPTR: Protein of hypothetical function DUF1016; IMG reference gene:2504771614; PFAM: Protein of unknown function (DUF1016).
 
     0.517
AEE51761.1
COGs: COG1373 ATPase (AAA+ superfamily); InterPro IPR003593; KEGG: dfe:Dfer_3737 AAA ATPase; SMART: ATPase, AAA+ type, core; SPTR: AAA ATPase; IMG reference gene:2504773295.
  
     0.512
AEE50862.1
Filamentation induced by cAMP protein Fic; COGs: COG3177 conserved hypothetical protein; InterPro IPR003812; KEGG: bth:BT_2513 hypothetical protein; PFAM: Filamentation induced by cAMP/death on curing, related; SPTR: Filamentation induced by cAMP protein Fic; IMG reference gene:2504772373; PFAM: Fic/DOC family.
 
     0.471
AEE51394.1
COGs: COG1373 ATPase (AAA+ superfamily); KEGG: apa:APP7_0848 putative ATPase; SPTR: Putative uncharacterized protein; IMG reference gene:2504772920.
  
    0.467
AEE52283.1
COGs: COG1373 ATPase (AAA+ superfamily); InterPro IPR003593; KEGG: bfr:BF0135 hypothetical protein; SMART: ATPase, AAA+ type, core; SPTR: Putative uncharacterized protein; IMG reference gene:2504773828; PFAM: Archaeal ATPase.
  
     0.460
Your Current Organism:
Haliscomenobacter hydrossis
NCBI taxonomy Id: 760192
Other names: H. hydrossis DSM 1100, Haliscomenobacter hydrossis DSM 1100
Server load: low (20%) [HD]