| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AEE48784.1 | AEE50297.1 | Halhy_0880 | Halhy_2423 | Serine dehydratase alpha chain; COGs: COG1760 L-serine deaminase; InterPro IPR005131:IPR005130; KEGG: rba:RB8979 L-serine dehydratase, alpha chain; PFAM: Serine dehydratase alpha chain; Serine dehydratase beta chain; SPTR: Probable L-serine dehydratase, alpha chain; IMG reference gene:2504770240; PFAM: Serine dehydratase alpha chain; Serine dehydratase beta chain; TIGRFAM: L-serine dehydratase, iron-sulfur-dependent, beta subunit; L-serine dehydratase, iron-sulfur-dependent, alpha subunit. | COGs: COG1045 Serine acetyltransferase; InterPro IPR001451; KEGG: chu:CHU_0685 serine O-acetyltransferase; PRIAM: Serine O-acetyltransferase; SPTR: Serine O-acetyltransferase; IMG reference gene:2504771792; PFAM: Bacterial transferase hexapeptide (three repeats); TIGRFAM: serine O-acetyltransferase. | 0.908 |
| AEE48784.1 | AEE50854.1 | Halhy_0880 | Halhy_2990 | Serine dehydratase alpha chain; COGs: COG1760 L-serine deaminase; InterPro IPR005131:IPR005130; KEGG: rba:RB8979 L-serine dehydratase, alpha chain; PFAM: Serine dehydratase alpha chain; Serine dehydratase beta chain; SPTR: Probable L-serine dehydratase, alpha chain; IMG reference gene:2504770240; PFAM: Serine dehydratase alpha chain; Serine dehydratase beta chain; TIGRFAM: L-serine dehydratase, iron-sulfur-dependent, beta subunit; L-serine dehydratase, iron-sulfur-dependent, alpha subunit. | COGs: COG0527 Aspartokinase; InterProIPR001048:IPR002912:IPR005106:IPR001342:IPR 001341; KEGG: chu:CHU_0073 bifunctional aspartokinase I/homeserine dehydrogenase I; PFAM: Homoserine dehydrogenase, catalytic; Aspartate/glutamate/uridylate kinase; Amino acid-binding ACT; Aspartate/homoserine dehydrogenase, NAD-binding; PRIAM: Aspartate kinase., Homoserine dehydrogenase; SPTR: Bifunctional protein: aspartokinase I; homoserine dehydrogenase; TIGRFAM: Aspartate kinase region; IMG reference gene:2504772364; PFAM: Homoserine dehydrogenase; Homoserine dehydrogenase, NAD binding domain; ACT dom [...] | 0.833 |
| AEE48784.1 | AEE51799.1 | Halhy_0880 | Halhy_3951 | Serine dehydratase alpha chain; COGs: COG1760 L-serine deaminase; InterPro IPR005131:IPR005130; KEGG: rba:RB8979 L-serine dehydratase, alpha chain; PFAM: Serine dehydratase alpha chain; Serine dehydratase beta chain; SPTR: Probable L-serine dehydratase, alpha chain; IMG reference gene:2504770240; PFAM: Serine dehydratase alpha chain; Serine dehydratase beta chain; TIGRFAM: L-serine dehydratase, iron-sulfur-dependent, beta subunit; L-serine dehydratase, iron-sulfur-dependent, alpha subunit. | COGs: COG1760 L-serine deaminase; InterPro IPR004644:IPR005131:IPR005130; KEGG: fps:FP0884 L-serine ammonia-lyase; PFAM: Serine dehydratase alpha chain; Serine dehydratase beta chain; SPTR: L-serine ammonia-lyase; TIGRFAM: Iron-sulphur-dependent L-serine dehydratase single chain form; IMG reference gene:2504773336; PFAM: Serine dehydratase alpha chain; Serine dehydratase beta chain; TIGRFAM: L-serine dehydratase, iron-sulfur-dependent, beta subunit; L-serine dehydratase, iron-sulfur-dependent, single chain form. | 0.928 |
| AEE48784.1 | AEE54139.1 | Halhy_0880 | Halhy_6320 | Serine dehydratase alpha chain; COGs: COG1760 L-serine deaminase; InterPro IPR005131:IPR005130; KEGG: rba:RB8979 L-serine dehydratase, alpha chain; PFAM: Serine dehydratase alpha chain; Serine dehydratase beta chain; SPTR: Probable L-serine dehydratase, alpha chain; IMG reference gene:2504770240; PFAM: Serine dehydratase alpha chain; Serine dehydratase beta chain; TIGRFAM: L-serine dehydratase, iron-sulfur-dependent, beta subunit; L-serine dehydratase, iron-sulfur-dependent, alpha subunit. | COGs: COG0031 Cysteine synthase; InterPro IPR001926:IPR000644; KEGG: phe:Phep_1434 cysteine synthase; PFAM: Pyridoxal phosphate-dependent enzyme, beta subunit; Cystathionine beta-synthase, core; PRIAM: Cysteine synthase; SMART: Cystathionine beta-synthase, core; SPTR: Cystathionine beta-synthase; IMG reference gene:2504775728; PFAM: CBS domain; Pyridoxal-phosphate dependent enzyme; TIGRFAM: cystathionine beta-synthase. | 0.914 |
| AEE48784.1 | metXA | Halhy_0880 | Halhy_5551 | Serine dehydratase alpha chain; COGs: COG1760 L-serine deaminase; InterPro IPR005131:IPR005130; KEGG: rba:RB8979 L-serine dehydratase, alpha chain; PFAM: Serine dehydratase alpha chain; Serine dehydratase beta chain; SPTR: Probable L-serine dehydratase, alpha chain; IMG reference gene:2504770240; PFAM: Serine dehydratase alpha chain; Serine dehydratase beta chain; TIGRFAM: L-serine dehydratase, iron-sulfur-dependent, beta subunit; L-serine dehydratase, iron-sulfur-dependent, alpha subunit. | Homoserine O-acetyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine. | 0.806 |
| AEE48784.1 | thrB | Halhy_0880 | Halhy_2991 | Serine dehydratase alpha chain; COGs: COG1760 L-serine deaminase; InterPro IPR005131:IPR005130; KEGG: rba:RB8979 L-serine dehydratase, alpha chain; PFAM: Serine dehydratase alpha chain; Serine dehydratase beta chain; SPTR: Probable L-serine dehydratase, alpha chain; IMG reference gene:2504770240; PFAM: Serine dehydratase alpha chain; Serine dehydratase beta chain; TIGRFAM: L-serine dehydratase, iron-sulfur-dependent, beta subunit; L-serine dehydratase, iron-sulfur-dependent, alpha subunit. | Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. | 0.830 |
| AEE49983.1 | AEE50854.1 | Halhy_2098 | Halhy_2990 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | COGs: COG0527 Aspartokinase; InterProIPR001048:IPR002912:IPR005106:IPR001342:IPR 001341; KEGG: chu:CHU_0073 bifunctional aspartokinase I/homeserine dehydrogenase I; PFAM: Homoserine dehydrogenase, catalytic; Aspartate/glutamate/uridylate kinase; Amino acid-binding ACT; Aspartate/homoserine dehydrogenase, NAD-binding; PRIAM: Aspartate kinase., Homoserine dehydrogenase; SPTR: Bifunctional protein: aspartokinase I; homoserine dehydrogenase; TIGRFAM: Aspartate kinase region; IMG reference gene:2504772364; PFAM: Homoserine dehydrogenase; Homoserine dehydrogenase, NAD binding domain; ACT dom [...] | 0.958 |
| AEE49983.1 | AEE50856.1 | Halhy_2098 | Halhy_2992 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | COGs: COG0498 Threonine synthase; InterPro IPR001926:IPR004450; KEGG: dfe:Dfer_3806 threonine synthase; PFAM: Pyridoxal phosphate-dependent enzyme, beta subunit; PRIAM: Threonine synthase; SPTR: Threonine synthase; TIGRFAM: Threonine synthase; IMG reference gene:2504772366; PFAM: Pyridoxal-phosphate dependent enzyme; TIGRFAM: threonine synthase. | 0.501 |
| AEE49983.1 | AEE53450.1 | Halhy_2098 | Halhy_5627 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Aminotransferase class IV; COGs: COG0115 Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase; InterPro IPR001544; KEGG: cpi:Cpin_6961 aminotransferase class IV; PFAM: Aminotransferase, class IV; SPTR: Aminotransferase class IV; IMG reference gene:2504775025; PFAM: Aminotransferase class IV. | 0.441 |
| AEE49983.1 | AEE54139.1 | Halhy_2098 | Halhy_6320 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | COGs: COG0031 Cysteine synthase; InterPro IPR001926:IPR000644; KEGG: phe:Phep_1434 cysteine synthase; PFAM: Pyridoxal phosphate-dependent enzyme, beta subunit; Cystathionine beta-synthase, core; PRIAM: Cysteine synthase; SMART: Cystathionine beta-synthase, core; SPTR: Cystathionine beta-synthase; IMG reference gene:2504775728; PFAM: CBS domain; Pyridoxal-phosphate dependent enzyme; TIGRFAM: cystathionine beta-synthase. | 0.937 |
| AEE49983.1 | AEE54339.1 | Halhy_2098 | Halhy_6523 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | COGs: COG0115 Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase; InterPro IPR005786:IPR001544; KEGG: mtt:Ftrac_0939 branched chain amino acid aminotransferase apoenzyme; PFAM: Aminotransferase, class IV; PRIAM: Branched-chain-amino-acid transaminase; SPTR: Branched-chain amino acid aminotransferase; TIGRFAM: Branched-chain amino acid aminotransferase II; IMG reference gene:2504775932; PFAM: Aminotransferase class IV; TIGRFAM: branched-chain amino acid aminotransferase, group II; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. | 0.441 |
| AEE49983.1 | metXA | Halhy_2098 | Halhy_5551 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Homoserine O-acetyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine. | 0.694 |
| AEE49983.1 | thrB | Halhy_2098 | Halhy_2991 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. | 0.882 |
| AEE50297.1 | AEE48784.1 | Halhy_2423 | Halhy_0880 | COGs: COG1045 Serine acetyltransferase; InterPro IPR001451; KEGG: chu:CHU_0685 serine O-acetyltransferase; PRIAM: Serine O-acetyltransferase; SPTR: Serine O-acetyltransferase; IMG reference gene:2504771792; PFAM: Bacterial transferase hexapeptide (three repeats); TIGRFAM: serine O-acetyltransferase. | Serine dehydratase alpha chain; COGs: COG1760 L-serine deaminase; InterPro IPR005131:IPR005130; KEGG: rba:RB8979 L-serine dehydratase, alpha chain; PFAM: Serine dehydratase alpha chain; Serine dehydratase beta chain; SPTR: Probable L-serine dehydratase, alpha chain; IMG reference gene:2504770240; PFAM: Serine dehydratase alpha chain; Serine dehydratase beta chain; TIGRFAM: L-serine dehydratase, iron-sulfur-dependent, beta subunit; L-serine dehydratase, iron-sulfur-dependent, alpha subunit. | 0.908 |
| AEE50297.1 | AEE50854.1 | Halhy_2423 | Halhy_2990 | COGs: COG1045 Serine acetyltransferase; InterPro IPR001451; KEGG: chu:CHU_0685 serine O-acetyltransferase; PRIAM: Serine O-acetyltransferase; SPTR: Serine O-acetyltransferase; IMG reference gene:2504771792; PFAM: Bacterial transferase hexapeptide (three repeats); TIGRFAM: serine O-acetyltransferase. | COGs: COG0527 Aspartokinase; InterProIPR001048:IPR002912:IPR005106:IPR001342:IPR 001341; KEGG: chu:CHU_0073 bifunctional aspartokinase I/homeserine dehydrogenase I; PFAM: Homoserine dehydrogenase, catalytic; Aspartate/glutamate/uridylate kinase; Amino acid-binding ACT; Aspartate/homoserine dehydrogenase, NAD-binding; PRIAM: Aspartate kinase., Homoserine dehydrogenase; SPTR: Bifunctional protein: aspartokinase I; homoserine dehydrogenase; TIGRFAM: Aspartate kinase region; IMG reference gene:2504772364; PFAM: Homoserine dehydrogenase; Homoserine dehydrogenase, NAD binding domain; ACT dom [...] | 0.863 |
| AEE50297.1 | AEE51799.1 | Halhy_2423 | Halhy_3951 | COGs: COG1045 Serine acetyltransferase; InterPro IPR001451; KEGG: chu:CHU_0685 serine O-acetyltransferase; PRIAM: Serine O-acetyltransferase; SPTR: Serine O-acetyltransferase; IMG reference gene:2504771792; PFAM: Bacterial transferase hexapeptide (three repeats); TIGRFAM: serine O-acetyltransferase. | COGs: COG1760 L-serine deaminase; InterPro IPR004644:IPR005131:IPR005130; KEGG: fps:FP0884 L-serine ammonia-lyase; PFAM: Serine dehydratase alpha chain; Serine dehydratase beta chain; SPTR: L-serine ammonia-lyase; TIGRFAM: Iron-sulphur-dependent L-serine dehydratase single chain form; IMG reference gene:2504773336; PFAM: Serine dehydratase alpha chain; Serine dehydratase beta chain; TIGRFAM: L-serine dehydratase, iron-sulfur-dependent, beta subunit; L-serine dehydratase, iron-sulfur-dependent, single chain form. | 0.908 |
| AEE50297.1 | AEE54139.1 | Halhy_2423 | Halhy_6320 | COGs: COG1045 Serine acetyltransferase; InterPro IPR001451; KEGG: chu:CHU_0685 serine O-acetyltransferase; PRIAM: Serine O-acetyltransferase; SPTR: Serine O-acetyltransferase; IMG reference gene:2504771792; PFAM: Bacterial transferase hexapeptide (three repeats); TIGRFAM: serine O-acetyltransferase. | COGs: COG0031 Cysteine synthase; InterPro IPR001926:IPR000644; KEGG: phe:Phep_1434 cysteine synthase; PFAM: Pyridoxal phosphate-dependent enzyme, beta subunit; Cystathionine beta-synthase, core; PRIAM: Cysteine synthase; SMART: Cystathionine beta-synthase, core; SPTR: Cystathionine beta-synthase; IMG reference gene:2504775728; PFAM: CBS domain; Pyridoxal-phosphate dependent enzyme; TIGRFAM: cystathionine beta-synthase. | 0.942 |
| AEE50297.1 | thrB | Halhy_2423 | Halhy_2991 | COGs: COG1045 Serine acetyltransferase; InterPro IPR001451; KEGG: chu:CHU_0685 serine O-acetyltransferase; PRIAM: Serine O-acetyltransferase; SPTR: Serine O-acetyltransferase; IMG reference gene:2504771792; PFAM: Bacterial transferase hexapeptide (three repeats); TIGRFAM: serine O-acetyltransferase. | Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. | 0.826 |
| AEE50854.1 | AEE48784.1 | Halhy_2990 | Halhy_0880 | COGs: COG0527 Aspartokinase; InterProIPR001048:IPR002912:IPR005106:IPR001342:IPR 001341; KEGG: chu:CHU_0073 bifunctional aspartokinase I/homeserine dehydrogenase I; PFAM: Homoserine dehydrogenase, catalytic; Aspartate/glutamate/uridylate kinase; Amino acid-binding ACT; Aspartate/homoserine dehydrogenase, NAD-binding; PRIAM: Aspartate kinase., Homoserine dehydrogenase; SPTR: Bifunctional protein: aspartokinase I; homoserine dehydrogenase; TIGRFAM: Aspartate kinase region; IMG reference gene:2504772364; PFAM: Homoserine dehydrogenase; Homoserine dehydrogenase, NAD binding domain; ACT dom [...] | Serine dehydratase alpha chain; COGs: COG1760 L-serine deaminase; InterPro IPR005131:IPR005130; KEGG: rba:RB8979 L-serine dehydratase, alpha chain; PFAM: Serine dehydratase alpha chain; Serine dehydratase beta chain; SPTR: Probable L-serine dehydratase, alpha chain; IMG reference gene:2504770240; PFAM: Serine dehydratase alpha chain; Serine dehydratase beta chain; TIGRFAM: L-serine dehydratase, iron-sulfur-dependent, beta subunit; L-serine dehydratase, iron-sulfur-dependent, alpha subunit. | 0.833 |
| AEE50854.1 | AEE49983.1 | Halhy_2990 | Halhy_2098 | COGs: COG0527 Aspartokinase; InterProIPR001048:IPR002912:IPR005106:IPR001342:IPR 001341; KEGG: chu:CHU_0073 bifunctional aspartokinase I/homeserine dehydrogenase I; PFAM: Homoserine dehydrogenase, catalytic; Aspartate/glutamate/uridylate kinase; Amino acid-binding ACT; Aspartate/homoserine dehydrogenase, NAD-binding; PRIAM: Aspartate kinase., Homoserine dehydrogenase; SPTR: Bifunctional protein: aspartokinase I; homoserine dehydrogenase; TIGRFAM: Aspartate kinase region; IMG reference gene:2504772364; PFAM: Homoserine dehydrogenase; Homoserine dehydrogenase, NAD binding domain; ACT dom [...] | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.958 |
