| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AEE48249.1 | AEE49149.1 | Halhy_0337 | Halhy_1254 | Transketolase; COGs: COG0021 Transketolase; InterPro IPR005474:IPR005475; KEGG: fbc:FB2170_14593 transketolase; PFAM: Transketolase, N-terminal; Transketolase-like, pyrimidine-binding domain; PRIAM: Transketolase; SPTR: Transketolase; IMG reference gene:2504769692; PFAM: Transketolase, thiamine diphosphate binding domain; Transketolase, pyrimidine binding domain; Belongs to the transketolase family. | Phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; COGs: COG1109 Phosphomannomutase; InterPro IPR005844:IPR005845:IPR005846; KEGG: sli:Slin_2990 phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; PFAM: Alpha-D-phosphohexomutase, alpha/beta/alpha domain I; Alpha-D-phosphohexomutase, alpha/beta/alpha domain II; Alpha-D-phosphohexomutase, alpha/beta/alpha domain III; SPTR: Phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; IMG reference gene:2504770615; PFAM: Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II; Phosphoglucomutase/pho [...] | 0.924 |
| AEE48249.1 | AEE49727.1 | Halhy_0337 | Halhy_1842 | Transketolase; COGs: COG0021 Transketolase; InterPro IPR005474:IPR005475; KEGG: fbc:FB2170_14593 transketolase; PFAM: Transketolase, N-terminal; Transketolase-like, pyrimidine-binding domain; PRIAM: Transketolase; SPTR: Transketolase; IMG reference gene:2504769692; PFAM: Transketolase, thiamine diphosphate binding domain; Transketolase, pyrimidine binding domain; Belongs to the transketolase family. | COGs: COG0036 Pentose-5-phosphate-3-epimerase; InterPro IPR000056; KEGG: chu:CHU_1605 ribulose-phosphate 3-epimerase (D-ribulose-5-phosphate 3-epimerase); PFAM: Ribulose-phosphate 3-epimerase; PRIAM: Ribulose-phosphate 3-epimerase; SPTR: Ribulose-phosphate 3-epimerase; TIGRFAM: Ribulose-phosphate 3-epimerase; IMG reference gene:2504771203; PFAM: Ribulose-phosphate 3 epimerase family; TIGRFAM: ribulose-phosphate 3-epimerase. | 0.973 |
| AEE48249.1 | AEE50521.1 | Halhy_0337 | Halhy_2652 | Transketolase; COGs: COG0021 Transketolase; InterPro IPR005474:IPR005475; KEGG: fbc:FB2170_14593 transketolase; PFAM: Transketolase, N-terminal; Transketolase-like, pyrimidine-binding domain; PRIAM: Transketolase; SPTR: Transketolase; IMG reference gene:2504769692; PFAM: Transketolase, thiamine diphosphate binding domain; Transketolase, pyrimidine binding domain; Belongs to the transketolase family. | 6-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. | 0.924 |
| AEE48249.1 | AEE50522.1 | Halhy_0337 | Halhy_2653 | Transketolase; COGs: COG0021 Transketolase; InterPro IPR005474:IPR005475; KEGG: fbc:FB2170_14593 transketolase; PFAM: Transketolase, N-terminal; Transketolase-like, pyrimidine-binding domain; PRIAM: Transketolase; SPTR: Transketolase; IMG reference gene:2504769692; PFAM: Transketolase, thiamine diphosphate binding domain; Transketolase, pyrimidine binding domain; Belongs to the transketolase family. | Sugar-phosphate isomerase, RpiB/LacA/LacB family; COGs: COG0698 Ribose 5-phosphate isomerase RpiB; InterPro IPR003500; KEGG: gme:Gmet_2621 ribose/galactose isomerase; PFAM: Ribose/galactose isomerase; PRIAM: Ribose-5-phosphate isomerase; SPTR: Ribose/galactose isomerase; TIGRFAM: Ribose/galactose isomerase; IMG reference gene:2504772024; PFAM: Ribose/Galactose Isomerase; TIGRFAM: sugar-phosphate isomerases, RpiB/LacA/LacB family. | 0.924 |
| AEE48249.1 | AEE50912.1 | Halhy_0337 | Halhy_3049 | Transketolase; COGs: COG0021 Transketolase; InterPro IPR005474:IPR005475; KEGG: fbc:FB2170_14593 transketolase; PFAM: Transketolase, N-terminal; Transketolase-like, pyrimidine-binding domain; PRIAM: Transketolase; SPTR: Transketolase; IMG reference gene:2504769692; PFAM: Transketolase, thiamine diphosphate binding domain; Transketolase, pyrimidine binding domain; Belongs to the transketolase family. | Sugar-phosphate isomerase, RpiB/LacA/LacB family; COGs: COG0698 Ribose 5-phosphate isomerase RpiB; InterPro IPR003500:IPR004785; KEGG: sugar-phosphate isomerase, RpiB/LacA/LacB family; PFAM: Ribose/galactose isomerase; PRIAM: Ribose-5-phosphate isomerase; SPTR: Ribose-5-phosphate isomerase; TIGRFAM: Ribose/galactose isomerase; Ribose 5-phosphate isomerase B; IMG reference gene:2504772428; PFAM: Ribose/Galactose Isomerase; TIGRFAM: ribose 5-phosphate isomerase B; sugar-phosphate isomerases, RpiB/LacA/LacB family. | 0.929 |
| AEE48249.1 | AEE52011.1 | Halhy_0337 | Halhy_4165 | Transketolase; COGs: COG0021 Transketolase; InterPro IPR005474:IPR005475; KEGG: fbc:FB2170_14593 transketolase; PFAM: Transketolase, N-terminal; Transketolase-like, pyrimidine-binding domain; PRIAM: Transketolase; SPTR: Transketolase; IMG reference gene:2504769692; PFAM: Transketolase, thiamine diphosphate binding domain; Transketolase, pyrimidine binding domain; Belongs to the transketolase family. | Ribose-phosphate pyrophosphokinase; COGs: COG0462 Phosphoribosylpyrophosphate synthetase; InterPro IPR000836:IPR005946; KEGG: mtt:Ftrac_0551 ribose-phosphate pyrophosphokinase; PFAM: Phosphoribosyltransferase; PRIAM: Ribose-phosphate diphosphokinase; SPTR: Ribose-phosphate pyrophosphokinase; TIGRFAM: Phosphoribosyl pyrophosphokinase; IMG reference gene:2504773551; PFAM: Phosphoribosyl transferase domain; TIGRFAM: ribose-phosphate pyrophosphokinase. | 0.946 |
| AEE48249.1 | glyA | Halhy_0337 | Halhy_2715 | Transketolase; COGs: COG0021 Transketolase; InterPro IPR005474:IPR005475; KEGG: fbc:FB2170_14593 transketolase; PFAM: Transketolase, N-terminal; Transketolase-like, pyrimidine-binding domain; PRIAM: Transketolase; SPTR: Transketolase; IMG reference gene:2504769692; PFAM: Transketolase, thiamine diphosphate binding domain; Transketolase, pyrimidine binding domain; Belongs to the transketolase family. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.459 |
| AEE48249.1 | rbsK | Halhy_0337 | Halhy_5191 | Transketolase; COGs: COG0021 Transketolase; InterPro IPR005474:IPR005475; KEGG: fbc:FB2170_14593 transketolase; PFAM: Transketolase, N-terminal; Transketolase-like, pyrimidine-binding domain; PRIAM: Transketolase; SPTR: Transketolase; IMG reference gene:2504769692; PFAM: Transketolase, thiamine diphosphate binding domain; Transketolase, pyrimidine binding domain; Belongs to the transketolase family. | Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. | 0.921 |
| AEE49149.1 | AEE48249.1 | Halhy_1254 | Halhy_0337 | Phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; COGs: COG1109 Phosphomannomutase; InterPro IPR005844:IPR005845:IPR005846; KEGG: sli:Slin_2990 phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; PFAM: Alpha-D-phosphohexomutase, alpha/beta/alpha domain I; Alpha-D-phosphohexomutase, alpha/beta/alpha domain II; Alpha-D-phosphohexomutase, alpha/beta/alpha domain III; SPTR: Phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; IMG reference gene:2504770615; PFAM: Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II; Phosphoglucomutase/pho [...] | Transketolase; COGs: COG0021 Transketolase; InterPro IPR005474:IPR005475; KEGG: fbc:FB2170_14593 transketolase; PFAM: Transketolase, N-terminal; Transketolase-like, pyrimidine-binding domain; PRIAM: Transketolase; SPTR: Transketolase; IMG reference gene:2504769692; PFAM: Transketolase, thiamine diphosphate binding domain; Transketolase, pyrimidine binding domain; Belongs to the transketolase family. | 0.924 |
| AEE49149.1 | AEE50522.1 | Halhy_1254 | Halhy_2653 | Phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; COGs: COG1109 Phosphomannomutase; InterPro IPR005844:IPR005845:IPR005846; KEGG: sli:Slin_2990 phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; PFAM: Alpha-D-phosphohexomutase, alpha/beta/alpha domain I; Alpha-D-phosphohexomutase, alpha/beta/alpha domain II; Alpha-D-phosphohexomutase, alpha/beta/alpha domain III; SPTR: Phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; IMG reference gene:2504770615; PFAM: Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II; Phosphoglucomutase/pho [...] | Sugar-phosphate isomerase, RpiB/LacA/LacB family; COGs: COG0698 Ribose 5-phosphate isomerase RpiB; InterPro IPR003500; KEGG: gme:Gmet_2621 ribose/galactose isomerase; PFAM: Ribose/galactose isomerase; PRIAM: Ribose-5-phosphate isomerase; SPTR: Ribose/galactose isomerase; TIGRFAM: Ribose/galactose isomerase; IMG reference gene:2504772024; PFAM: Ribose/Galactose Isomerase; TIGRFAM: sugar-phosphate isomerases, RpiB/LacA/LacB family. | 0.904 |
| AEE49149.1 | AEE50912.1 | Halhy_1254 | Halhy_3049 | Phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; COGs: COG1109 Phosphomannomutase; InterPro IPR005844:IPR005845:IPR005846; KEGG: sli:Slin_2990 phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; PFAM: Alpha-D-phosphohexomutase, alpha/beta/alpha domain I; Alpha-D-phosphohexomutase, alpha/beta/alpha domain II; Alpha-D-phosphohexomutase, alpha/beta/alpha domain III; SPTR: Phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; IMG reference gene:2504770615; PFAM: Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II; Phosphoglucomutase/pho [...] | Sugar-phosphate isomerase, RpiB/LacA/LacB family; COGs: COG0698 Ribose 5-phosphate isomerase RpiB; InterPro IPR003500:IPR004785; KEGG: sugar-phosphate isomerase, RpiB/LacA/LacB family; PFAM: Ribose/galactose isomerase; PRIAM: Ribose-5-phosphate isomerase; SPTR: Ribose-5-phosphate isomerase; TIGRFAM: Ribose/galactose isomerase; Ribose 5-phosphate isomerase B; IMG reference gene:2504772428; PFAM: Ribose/Galactose Isomerase; TIGRFAM: ribose 5-phosphate isomerase B; sugar-phosphate isomerases, RpiB/LacA/LacB family. | 0.904 |
| AEE49149.1 | AEE52011.1 | Halhy_1254 | Halhy_4165 | Phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; COGs: COG1109 Phosphomannomutase; InterPro IPR005844:IPR005845:IPR005846; KEGG: sli:Slin_2990 phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; PFAM: Alpha-D-phosphohexomutase, alpha/beta/alpha domain I; Alpha-D-phosphohexomutase, alpha/beta/alpha domain II; Alpha-D-phosphohexomutase, alpha/beta/alpha domain III; SPTR: Phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; IMG reference gene:2504770615; PFAM: Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II; Phosphoglucomutase/pho [...] | Ribose-phosphate pyrophosphokinase; COGs: COG0462 Phosphoribosylpyrophosphate synthetase; InterPro IPR000836:IPR005946; KEGG: mtt:Ftrac_0551 ribose-phosphate pyrophosphokinase; PFAM: Phosphoribosyltransferase; PRIAM: Ribose-phosphate diphosphokinase; SPTR: Ribose-phosphate pyrophosphokinase; TIGRFAM: Phosphoribosyl pyrophosphokinase; IMG reference gene:2504773551; PFAM: Phosphoribosyl transferase domain; TIGRFAM: ribose-phosphate pyrophosphokinase. | 0.923 |
| AEE49149.1 | rbsK | Halhy_1254 | Halhy_5191 | Phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; COGs: COG1109 Phosphomannomutase; InterPro IPR005844:IPR005845:IPR005846; KEGG: sli:Slin_2990 phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; PFAM: Alpha-D-phosphohexomutase, alpha/beta/alpha domain I; Alpha-D-phosphohexomutase, alpha/beta/alpha domain II; Alpha-D-phosphohexomutase, alpha/beta/alpha domain III; SPTR: Phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; IMG reference gene:2504770615; PFAM: Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II; Phosphoglucomutase/pho [...] | Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. | 0.907 |
| AEE49727.1 | AEE48249.1 | Halhy_1842 | Halhy_0337 | COGs: COG0036 Pentose-5-phosphate-3-epimerase; InterPro IPR000056; KEGG: chu:CHU_1605 ribulose-phosphate 3-epimerase (D-ribulose-5-phosphate 3-epimerase); PFAM: Ribulose-phosphate 3-epimerase; PRIAM: Ribulose-phosphate 3-epimerase; SPTR: Ribulose-phosphate 3-epimerase; TIGRFAM: Ribulose-phosphate 3-epimerase; IMG reference gene:2504771203; PFAM: Ribulose-phosphate 3 epimerase family; TIGRFAM: ribulose-phosphate 3-epimerase. | Transketolase; COGs: COG0021 Transketolase; InterPro IPR005474:IPR005475; KEGG: fbc:FB2170_14593 transketolase; PFAM: Transketolase, N-terminal; Transketolase-like, pyrimidine-binding domain; PRIAM: Transketolase; SPTR: Transketolase; IMG reference gene:2504769692; PFAM: Transketolase, thiamine diphosphate binding domain; Transketolase, pyrimidine binding domain; Belongs to the transketolase family. | 0.973 |
| AEE49727.1 | AEE50521.1 | Halhy_1842 | Halhy_2652 | COGs: COG0036 Pentose-5-phosphate-3-epimerase; InterPro IPR000056; KEGG: chu:CHU_1605 ribulose-phosphate 3-epimerase (D-ribulose-5-phosphate 3-epimerase); PFAM: Ribulose-phosphate 3-epimerase; PRIAM: Ribulose-phosphate 3-epimerase; SPTR: Ribulose-phosphate 3-epimerase; TIGRFAM: Ribulose-phosphate 3-epimerase; IMG reference gene:2504771203; PFAM: Ribulose-phosphate 3 epimerase family; TIGRFAM: ribulose-phosphate 3-epimerase. | 6-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. | 0.953 |
| AEE49727.1 | AEE50522.1 | Halhy_1842 | Halhy_2653 | COGs: COG0036 Pentose-5-phosphate-3-epimerase; InterPro IPR000056; KEGG: chu:CHU_1605 ribulose-phosphate 3-epimerase (D-ribulose-5-phosphate 3-epimerase); PFAM: Ribulose-phosphate 3-epimerase; PRIAM: Ribulose-phosphate 3-epimerase; SPTR: Ribulose-phosphate 3-epimerase; TIGRFAM: Ribulose-phosphate 3-epimerase; IMG reference gene:2504771203; PFAM: Ribulose-phosphate 3 epimerase family; TIGRFAM: ribulose-phosphate 3-epimerase. | Sugar-phosphate isomerase, RpiB/LacA/LacB family; COGs: COG0698 Ribose 5-phosphate isomerase RpiB; InterPro IPR003500; KEGG: gme:Gmet_2621 ribose/galactose isomerase; PFAM: Ribose/galactose isomerase; PRIAM: Ribose-5-phosphate isomerase; SPTR: Ribose/galactose isomerase; TIGRFAM: Ribose/galactose isomerase; IMG reference gene:2504772024; PFAM: Ribose/Galactose Isomerase; TIGRFAM: sugar-phosphate isomerases, RpiB/LacA/LacB family. | 0.935 |
| AEE49727.1 | AEE50912.1 | Halhy_1842 | Halhy_3049 | COGs: COG0036 Pentose-5-phosphate-3-epimerase; InterPro IPR000056; KEGG: chu:CHU_1605 ribulose-phosphate 3-epimerase (D-ribulose-5-phosphate 3-epimerase); PFAM: Ribulose-phosphate 3-epimerase; PRIAM: Ribulose-phosphate 3-epimerase; SPTR: Ribulose-phosphate 3-epimerase; TIGRFAM: Ribulose-phosphate 3-epimerase; IMG reference gene:2504771203; PFAM: Ribulose-phosphate 3 epimerase family; TIGRFAM: ribulose-phosphate 3-epimerase. | Sugar-phosphate isomerase, RpiB/LacA/LacB family; COGs: COG0698 Ribose 5-phosphate isomerase RpiB; InterPro IPR003500:IPR004785; KEGG: sugar-phosphate isomerase, RpiB/LacA/LacB family; PFAM: Ribose/galactose isomerase; PRIAM: Ribose-5-phosphate isomerase; SPTR: Ribose-5-phosphate isomerase; TIGRFAM: Ribose/galactose isomerase; Ribose 5-phosphate isomerase B; IMG reference gene:2504772428; PFAM: Ribose/Galactose Isomerase; TIGRFAM: ribose 5-phosphate isomerase B; sugar-phosphate isomerases, RpiB/LacA/LacB family. | 0.937 |
| AEE49727.1 | AEE52011.1 | Halhy_1842 | Halhy_4165 | COGs: COG0036 Pentose-5-phosphate-3-epimerase; InterPro IPR000056; KEGG: chu:CHU_1605 ribulose-phosphate 3-epimerase (D-ribulose-5-phosphate 3-epimerase); PFAM: Ribulose-phosphate 3-epimerase; PRIAM: Ribulose-phosphate 3-epimerase; SPTR: Ribulose-phosphate 3-epimerase; TIGRFAM: Ribulose-phosphate 3-epimerase; IMG reference gene:2504771203; PFAM: Ribulose-phosphate 3 epimerase family; TIGRFAM: ribulose-phosphate 3-epimerase. | Ribose-phosphate pyrophosphokinase; COGs: COG0462 Phosphoribosylpyrophosphate synthetase; InterPro IPR000836:IPR005946; KEGG: mtt:Ftrac_0551 ribose-phosphate pyrophosphokinase; PFAM: Phosphoribosyltransferase; PRIAM: Ribose-phosphate diphosphokinase; SPTR: Ribose-phosphate pyrophosphokinase; TIGRFAM: Phosphoribosyl pyrophosphokinase; IMG reference gene:2504773551; PFAM: Phosphoribosyl transferase domain; TIGRFAM: ribose-phosphate pyrophosphokinase. | 0.641 |
| AEE49727.1 | AEE52243.1 | Halhy_1842 | Halhy_4399 | COGs: COG0036 Pentose-5-phosphate-3-epimerase; InterPro IPR000056; KEGG: chu:CHU_1605 ribulose-phosphate 3-epimerase (D-ribulose-5-phosphate 3-epimerase); PFAM: Ribulose-phosphate 3-epimerase; PRIAM: Ribulose-phosphate 3-epimerase; SPTR: Ribulose-phosphate 3-epimerase; TIGRFAM: Ribulose-phosphate 3-epimerase; IMG reference gene:2504771203; PFAM: Ribulose-phosphate 3 epimerase family; TIGRFAM: ribulose-phosphate 3-epimerase. | COGs: COG2721 Altronate dehydratase; InterPro IPR007392; KEGG: sli:Slin_4785 altronate dehydratase; PFAM: D-galactarate dehydratase/Altronate hydrolase, C-terminal; PRIAM: Altronate dehydratase; SPTR: Altronate dehydratase; IMG reference gene:2504773786; PFAM: SAF domain; D-galactarate dehydratase / Altronate hydrolase, C terminus. | 0.809 |
| AEE50521.1 | AEE48249.1 | Halhy_2652 | Halhy_0337 | 6-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. | Transketolase; COGs: COG0021 Transketolase; InterPro IPR005474:IPR005475; KEGG: fbc:FB2170_14593 transketolase; PFAM: Transketolase, N-terminal; Transketolase-like, pyrimidine-binding domain; PRIAM: Transketolase; SPTR: Transketolase; IMG reference gene:2504769692; PFAM: Transketolase, thiamine diphosphate binding domain; Transketolase, pyrimidine binding domain; Belongs to the transketolase family. | 0.924 |
