| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AEE50663.1 | AEE51018.1 | Halhy_2795 | Halhy_3157 | Helicase domain-containing protein; COGs: COG0513 Superfamily II DNA and RNA helicase; InterPro IPR014001:IPR001650:IPR000330; KEGG: pph:Ppha_1422 helicase domain protein; PFAM: DNA/RNA helicase, C-terminal; SNF2-related; SMART: DNA/RNA helicase, C-terminal; DEAD-like helicase, N-terminal; SPTR: Helicase-like; IMG reference gene:2504772166; PFAM: Helicase conserved C-terminal domain; SNF2 family N-terminal domain. | Peptidyl-prolyl cis-trans isomerase cyclophilin type; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. | 0.779 |
| AEE50663.1 | AEE51226.1 | Halhy_2795 | Halhy_3368 | Helicase domain-containing protein; COGs: COG0513 Superfamily II DNA and RNA helicase; InterPro IPR014001:IPR001650:IPR000330; KEGG: pph:Ppha_1422 helicase domain protein; PFAM: DNA/RNA helicase, C-terminal; SNF2-related; SMART: DNA/RNA helicase, C-terminal; DEAD-like helicase, N-terminal; SPTR: Helicase-like; IMG reference gene:2504772166; PFAM: Helicase conserved C-terminal domain; SNF2 family N-terminal domain. | KEGG: dfe:Dfer_1265 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504772748. | 0.773 |
| AEE50663.1 | dnaJ | Halhy_2795 | Halhy_3807 | Helicase domain-containing protein; COGs: COG0513 Superfamily II DNA and RNA helicase; InterPro IPR014001:IPR001650:IPR000330; KEGG: pph:Ppha_1422 helicase domain protein; PFAM: DNA/RNA helicase, C-terminal; SNF2-related; SMART: DNA/RNA helicase, C-terminal; DEAD-like helicase, N-terminal; SPTR: Helicase-like; IMG reference gene:2504772166; PFAM: Helicase conserved C-terminal domain; SNF2 family N-terminal domain. | Chaperone protein dnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | 0.598 |
| AEE50663.1 | polA | Halhy_2795 | Halhy_3156 | Helicase domain-containing protein; COGs: COG0513 Superfamily II DNA and RNA helicase; InterPro IPR014001:IPR001650:IPR000330; KEGG: pph:Ppha_1422 helicase domain protein; PFAM: DNA/RNA helicase, C-terminal; SNF2-related; SMART: DNA/RNA helicase, C-terminal; DEAD-like helicase, N-terminal; SPTR: Helicase-like; IMG reference gene:2504772166; PFAM: Helicase conserved C-terminal domain; SNF2 family N-terminal domain. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.828 |
| AEE50663.1 | rplB | Halhy_2795 | Halhy_4745 | Helicase domain-containing protein; COGs: COG0513 Superfamily II DNA and RNA helicase; InterPro IPR014001:IPR001650:IPR000330; KEGG: pph:Ppha_1422 helicase domain protein; PFAM: DNA/RNA helicase, C-terminal; SNF2-related; SMART: DNA/RNA helicase, C-terminal; DEAD-like helicase, N-terminal; SPTR: Helicase-like; IMG reference gene:2504772166; PFAM: Helicase conserved C-terminal domain; SNF2 family N-terminal domain. | Ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family. | 0.717 |
| AEE50663.1 | rplC | Halhy_2795 | Halhy_4742 | Helicase domain-containing protein; COGs: COG0513 Superfamily II DNA and RNA helicase; InterPro IPR014001:IPR001650:IPR000330; KEGG: pph:Ppha_1422 helicase domain protein; PFAM: DNA/RNA helicase, C-terminal; SNF2-related; SMART: DNA/RNA helicase, C-terminal; DEAD-like helicase, N-terminal; SPTR: Helicase-like; IMG reference gene:2504772166; PFAM: Helicase conserved C-terminal domain; SNF2 family N-terminal domain. | 50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. | 0.876 |
| AEE50663.1 | rplM | Halhy_2795 | Halhy_2728 | Helicase domain-containing protein; COGs: COG0513 Superfamily II DNA and RNA helicase; InterPro IPR014001:IPR001650:IPR000330; KEGG: pph:Ppha_1422 helicase domain protein; PFAM: DNA/RNA helicase, C-terminal; SNF2-related; SMART: DNA/RNA helicase, C-terminal; DEAD-like helicase, N-terminal; SPTR: Helicase-like; IMG reference gene:2504772166; PFAM: Helicase conserved C-terminal domain; SNF2 family N-terminal domain. | Ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. | 0.822 |
| AEE50663.1 | rplN | Halhy_2795 | Halhy_4752 | Helicase domain-containing protein; COGs: COG0513 Superfamily II DNA and RNA helicase; InterPro IPR014001:IPR001650:IPR000330; KEGG: pph:Ppha_1422 helicase domain protein; PFAM: DNA/RNA helicase, C-terminal; SNF2-related; SMART: DNA/RNA helicase, C-terminal; DEAD-like helicase, N-terminal; SPTR: Helicase-like; IMG reference gene:2504772166; PFAM: Helicase conserved C-terminal domain; SNF2 family N-terminal domain. | Ribosomal protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family. | 0.643 |
| AEE51018.1 | AEE50663.1 | Halhy_3157 | Halhy_2795 | Peptidyl-prolyl cis-trans isomerase cyclophilin type; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. | Helicase domain-containing protein; COGs: COG0513 Superfamily II DNA and RNA helicase; InterPro IPR014001:IPR001650:IPR000330; KEGG: pph:Ppha_1422 helicase domain protein; PFAM: DNA/RNA helicase, C-terminal; SNF2-related; SMART: DNA/RNA helicase, C-terminal; DEAD-like helicase, N-terminal; SPTR: Helicase-like; IMG reference gene:2504772166; PFAM: Helicase conserved C-terminal domain; SNF2 family N-terminal domain. | 0.779 |
| AEE51018.1 | AEE51019.1 | Halhy_3157 | Halhy_3158 | Peptidyl-prolyl cis-trans isomerase cyclophilin type; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. | COGs: COG1835 acyltransferase; InterPro IPR002656; KEGG: mgm:Mmc1_1144 acyltransferase 3; PFAM: Acyltransferase 3; SPTR: Acyltransferase 3; IMG reference gene:2504772538; PFAM: Acyltransferase family. | 0.773 |
| AEE51018.1 | AEE51226.1 | Halhy_3157 | Halhy_3368 | Peptidyl-prolyl cis-trans isomerase cyclophilin type; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. | KEGG: dfe:Dfer_1265 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504772748. | 0.564 |
| AEE51018.1 | dnaJ | Halhy_3157 | Halhy_3807 | Peptidyl-prolyl cis-trans isomerase cyclophilin type; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. | Chaperone protein dnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | 0.625 |
| AEE51018.1 | ndk | Halhy_3157 | Halhy_0350 | Peptidyl-prolyl cis-trans isomerase cyclophilin type; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.615 |
| AEE51018.1 | polA | Halhy_3157 | Halhy_3156 | Peptidyl-prolyl cis-trans isomerase cyclophilin type; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.755 |
| AEE51018.1 | rplB | Halhy_3157 | Halhy_4745 | Peptidyl-prolyl cis-trans isomerase cyclophilin type; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. | Ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family. | 0.559 |
| AEE51018.1 | rplC | Halhy_3157 | Halhy_4742 | Peptidyl-prolyl cis-trans isomerase cyclophilin type; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. | 50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. | 0.552 |
| AEE51018.1 | rplM | Halhy_3157 | Halhy_2728 | Peptidyl-prolyl cis-trans isomerase cyclophilin type; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. | Ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. | 0.547 |
| AEE51018.1 | rplN | Halhy_3157 | Halhy_4752 | Peptidyl-prolyl cis-trans isomerase cyclophilin type; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. | Ribosomal protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family. | 0.575 |
| AEE51019.1 | AEE51018.1 | Halhy_3158 | Halhy_3157 | COGs: COG1835 acyltransferase; InterPro IPR002656; KEGG: mgm:Mmc1_1144 acyltransferase 3; PFAM: Acyltransferase 3; SPTR: Acyltransferase 3; IMG reference gene:2504772538; PFAM: Acyltransferase family. | Peptidyl-prolyl cis-trans isomerase cyclophilin type; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. | 0.773 |
| AEE51019.1 | polA | Halhy_3158 | Halhy_3156 | COGs: COG1835 acyltransferase; InterPro IPR002656; KEGG: mgm:Mmc1_1144 acyltransferase 3; PFAM: Acyltransferase 3; SPTR: Acyltransferase 3; IMG reference gene:2504772538; PFAM: Acyltransferase family. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.704 |
