| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AEE48059.1 | AEE50985.1 | Halhy_0146 | Halhy_3123 | Sigma54 specific transcriptional regulator, Fis family; COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR003593:IPR002078:IPR002197; KEGG: cpi:Cpin_5917 sigma54 specific transcriptional regulator, fis family; PFAM: RNA polymerase sigma factor 54, interaction; Helix-turn-helix, Fis-type; SMART: ATPase, AAA+ type, core; SPTR: Sigma54 specific transcriptional regulator, Fis family; IMG reference gene:2504769498; PFAM: Bacterial regulatory protein, Fis family; Sigma-54 interaction domain. | Surface antigen (D15); COGs: COG4775 Outer membrane protein/protective antigen OMA87; InterPro IPR010827:IPR000184; KEGG: cpi:Cpin_1052 surface antigen variable number repeat protein; PFAM: Bacterial surface antigen (D15); Surface antigen variable number; SPTR: Bacterial surface antigen family protein; IMG reference gene:2504772503; PFAM: Surface antigen variable number repeat; TIGRFAM: outer membrane protein assembly complex, YaeT protein. | 0.414 |
| AEE48059.1 | AEE51182.1 | Halhy_0146 | Halhy_3323 | Sigma54 specific transcriptional regulator, Fis family; COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR003593:IPR002078:IPR002197; KEGG: cpi:Cpin_5917 sigma54 specific transcriptional regulator, fis family; PFAM: RNA polymerase sigma factor 54, interaction; Helix-turn-helix, Fis-type; SMART: ATPase, AAA+ type, core; SPTR: Sigma54 specific transcriptional regulator, Fis family; IMG reference gene:2504769498; PFAM: Bacterial regulatory protein, Fis family; Sigma-54 interaction domain. | 4-hydroxythreonine-4-phosphate dehydrogenase; COGs: COG1995 Pyridoxal phosphate biosynthesis protein; HAMAP: Pyridoxal phosphate (active vitamin B6) biosynthesis PdxA; InterPro IPR005255; KEGG: phe:Phep_3813 4-hydroxythreonine-4-phosphate dehydrogenase; PFAM: Pyridoxal phosphate (active vitamin B6) biosynthesis PdxA; PRIAM: 4-hydroxythreonine-4-phosphate dehydrogenase; SPTR: 4-hydroxythreonine-4-phosphate dehydrogenase; TIGRFAM: Pyridoxal phosphate (active vitamin B6) biosynthesis PdxA; IMG reference gene:2504772703; PFAM: Pyridoxal phosphate biosynthetic protein PdxA; TIGRFAM: 4-hydro [...] | 0.433 |
| AEE50985.1 | AEE48059.1 | Halhy_3123 | Halhy_0146 | Surface antigen (D15); COGs: COG4775 Outer membrane protein/protective antigen OMA87; InterPro IPR010827:IPR000184; KEGG: cpi:Cpin_1052 surface antigen variable number repeat protein; PFAM: Bacterial surface antigen (D15); Surface antigen variable number; SPTR: Bacterial surface antigen family protein; IMG reference gene:2504772503; PFAM: Surface antigen variable number repeat; TIGRFAM: outer membrane protein assembly complex, YaeT protein. | Sigma54 specific transcriptional regulator, Fis family; COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR003593:IPR002078:IPR002197; KEGG: cpi:Cpin_5917 sigma54 specific transcriptional regulator, fis family; PFAM: RNA polymerase sigma factor 54, interaction; Helix-turn-helix, Fis-type; SMART: ATPase, AAA+ type, core; SPTR: Sigma54 specific transcriptional regulator, Fis family; IMG reference gene:2504769498; PFAM: Bacterial regulatory protein, Fis family; Sigma-54 interaction domain. | 0.414 |
| AEE50985.1 | AEE51182.1 | Halhy_3123 | Halhy_3323 | Surface antigen (D15); COGs: COG4775 Outer membrane protein/protective antigen OMA87; InterPro IPR010827:IPR000184; KEGG: cpi:Cpin_1052 surface antigen variable number repeat protein; PFAM: Bacterial surface antigen (D15); Surface antigen variable number; SPTR: Bacterial surface antigen family protein; IMG reference gene:2504772503; PFAM: Surface antigen variable number repeat; TIGRFAM: outer membrane protein assembly complex, YaeT protein. | 4-hydroxythreonine-4-phosphate dehydrogenase; COGs: COG1995 Pyridoxal phosphate biosynthesis protein; HAMAP: Pyridoxal phosphate (active vitamin B6) biosynthesis PdxA; InterPro IPR005255; KEGG: phe:Phep_3813 4-hydroxythreonine-4-phosphate dehydrogenase; PFAM: Pyridoxal phosphate (active vitamin B6) biosynthesis PdxA; PRIAM: 4-hydroxythreonine-4-phosphate dehydrogenase; SPTR: 4-hydroxythreonine-4-phosphate dehydrogenase; TIGRFAM: Pyridoxal phosphate (active vitamin B6) biosynthesis PdxA; IMG reference gene:2504772703; PFAM: Pyridoxal phosphate biosynthetic protein PdxA; TIGRFAM: 4-hydro [...] | 0.489 |
| AEE50985.1 | AEE51856.1 | Halhy_3123 | Halhy_4008 | Surface antigen (D15); COGs: COG4775 Outer membrane protein/protective antigen OMA87; InterPro IPR010827:IPR000184; KEGG: cpi:Cpin_1052 surface antigen variable number repeat protein; PFAM: Bacterial surface antigen (D15); Surface antigen variable number; SPTR: Bacterial surface antigen family protein; IMG reference gene:2504772503; PFAM: Surface antigen variable number repeat; TIGRFAM: outer membrane protein assembly complex, YaeT protein. | Protein of unknown function DUF164; COGs: COG1579 Zn-ribbon protein possibly nucleic acid-binding; InterPro IPR003743; KEGG: cpi:Cpin_6895 protein of unknown function DUF164; PFAM: Protein of unknown function DUF164; SPTR: Putative uncharacterized protein; IMG reference gene:2504773393; PFAM: Putative zinc ribbon domain. | 0.725 |
| AEE50985.1 | lspA-2 | Halhy_3123 | Halhy_3324 | Surface antigen (D15); COGs: COG4775 Outer membrane protein/protective antigen OMA87; InterPro IPR010827:IPR000184; KEGG: cpi:Cpin_1052 surface antigen variable number repeat protein; PFAM: Bacterial surface antigen (D15); Surface antigen variable number; SPTR: Bacterial surface antigen family protein; IMG reference gene:2504772503; PFAM: Surface antigen variable number repeat; TIGRFAM: outer membrane protein assembly complex, YaeT protein. | Lipoprotein signal peptidase; This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family. | 0.642 |
| AEE50985.1 | pdxJ | Halhy_3123 | Halhy_4556 | Surface antigen (D15); COGs: COG4775 Outer membrane protein/protective antigen OMA87; InterPro IPR010827:IPR000184; KEGG: cpi:Cpin_1052 surface antigen variable number repeat protein; PFAM: Bacterial surface antigen (D15); Surface antigen variable number; SPTR: Bacterial surface antigen family protein; IMG reference gene:2504772503; PFAM: Surface antigen variable number repeat; TIGRFAM: outer membrane protein assembly complex, YaeT protein. | Pyridoxine 5'-phosphate synthase; Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino- 2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate. | 0.477 |
| AEE50985.1 | secF | Halhy_3123 | Halhy_6212 | Surface antigen (D15); COGs: COG4775 Outer membrane protein/protective antigen OMA87; InterPro IPR010827:IPR000184; KEGG: cpi:Cpin_1052 surface antigen variable number repeat protein; PFAM: Bacterial surface antigen (D15); Surface antigen variable number; SPTR: Bacterial surface antigen family protein; IMG reference gene:2504772503; PFAM: Surface antigen variable number repeat; TIGRFAM: outer membrane protein assembly complex, YaeT protein. | Protein-export membrane protein SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA; Belongs to the SecD/SecF family. SecD subfamily. | 0.422 |
| AEE51182.1 | AEE48059.1 | Halhy_3323 | Halhy_0146 | 4-hydroxythreonine-4-phosphate dehydrogenase; COGs: COG1995 Pyridoxal phosphate biosynthesis protein; HAMAP: Pyridoxal phosphate (active vitamin B6) biosynthesis PdxA; InterPro IPR005255; KEGG: phe:Phep_3813 4-hydroxythreonine-4-phosphate dehydrogenase; PFAM: Pyridoxal phosphate (active vitamin B6) biosynthesis PdxA; PRIAM: 4-hydroxythreonine-4-phosphate dehydrogenase; SPTR: 4-hydroxythreonine-4-phosphate dehydrogenase; TIGRFAM: Pyridoxal phosphate (active vitamin B6) biosynthesis PdxA; IMG reference gene:2504772703; PFAM: Pyridoxal phosphate biosynthetic protein PdxA; TIGRFAM: 4-hydro [...] | Sigma54 specific transcriptional regulator, Fis family; COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR003593:IPR002078:IPR002197; KEGG: cpi:Cpin_5917 sigma54 specific transcriptional regulator, fis family; PFAM: RNA polymerase sigma factor 54, interaction; Helix-turn-helix, Fis-type; SMART: ATPase, AAA+ type, core; SPTR: Sigma54 specific transcriptional regulator, Fis family; IMG reference gene:2504769498; PFAM: Bacterial regulatory protein, Fis family; Sigma-54 interaction domain. | 0.433 |
| AEE51182.1 | AEE50985.1 | Halhy_3323 | Halhy_3123 | 4-hydroxythreonine-4-phosphate dehydrogenase; COGs: COG1995 Pyridoxal phosphate biosynthesis protein; HAMAP: Pyridoxal phosphate (active vitamin B6) biosynthesis PdxA; InterPro IPR005255; KEGG: phe:Phep_3813 4-hydroxythreonine-4-phosphate dehydrogenase; PFAM: Pyridoxal phosphate (active vitamin B6) biosynthesis PdxA; PRIAM: 4-hydroxythreonine-4-phosphate dehydrogenase; SPTR: 4-hydroxythreonine-4-phosphate dehydrogenase; TIGRFAM: Pyridoxal phosphate (active vitamin B6) biosynthesis PdxA; IMG reference gene:2504772703; PFAM: Pyridoxal phosphate biosynthetic protein PdxA; TIGRFAM: 4-hydro [...] | Surface antigen (D15); COGs: COG4775 Outer membrane protein/protective antigen OMA87; InterPro IPR010827:IPR000184; KEGG: cpi:Cpin_1052 surface antigen variable number repeat protein; PFAM: Bacterial surface antigen (D15); Surface antigen variable number; SPTR: Bacterial surface antigen family protein; IMG reference gene:2504772503; PFAM: Surface antigen variable number repeat; TIGRFAM: outer membrane protein assembly complex, YaeT protein. | 0.489 |
| AEE51182.1 | AEE51856.1 | Halhy_3323 | Halhy_4008 | 4-hydroxythreonine-4-phosphate dehydrogenase; COGs: COG1995 Pyridoxal phosphate biosynthesis protein; HAMAP: Pyridoxal phosphate (active vitamin B6) biosynthesis PdxA; InterPro IPR005255; KEGG: phe:Phep_3813 4-hydroxythreonine-4-phosphate dehydrogenase; PFAM: Pyridoxal phosphate (active vitamin B6) biosynthesis PdxA; PRIAM: 4-hydroxythreonine-4-phosphate dehydrogenase; SPTR: 4-hydroxythreonine-4-phosphate dehydrogenase; TIGRFAM: Pyridoxal phosphate (active vitamin B6) biosynthesis PdxA; IMG reference gene:2504772703; PFAM: Pyridoxal phosphate biosynthetic protein PdxA; TIGRFAM: 4-hydro [...] | Protein of unknown function DUF164; COGs: COG1579 Zn-ribbon protein possibly nucleic acid-binding; InterPro IPR003743; KEGG: cpi:Cpin_6895 protein of unknown function DUF164; PFAM: Protein of unknown function DUF164; SPTR: Putative uncharacterized protein; IMG reference gene:2504773393; PFAM: Putative zinc ribbon domain. | 0.411 |
| AEE51182.1 | lspA-2 | Halhy_3323 | Halhy_3324 | 4-hydroxythreonine-4-phosphate dehydrogenase; COGs: COG1995 Pyridoxal phosphate biosynthesis protein; HAMAP: Pyridoxal phosphate (active vitamin B6) biosynthesis PdxA; InterPro IPR005255; KEGG: phe:Phep_3813 4-hydroxythreonine-4-phosphate dehydrogenase; PFAM: Pyridoxal phosphate (active vitamin B6) biosynthesis PdxA; PRIAM: 4-hydroxythreonine-4-phosphate dehydrogenase; SPTR: 4-hydroxythreonine-4-phosphate dehydrogenase; TIGRFAM: Pyridoxal phosphate (active vitamin B6) biosynthesis PdxA; IMG reference gene:2504772703; PFAM: Pyridoxal phosphate biosynthetic protein PdxA; TIGRFAM: 4-hydro [...] | Lipoprotein signal peptidase; This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family. | 0.742 |
| AEE51182.1 | pdxJ | Halhy_3323 | Halhy_4556 | 4-hydroxythreonine-4-phosphate dehydrogenase; COGs: COG1995 Pyridoxal phosphate biosynthesis protein; HAMAP: Pyridoxal phosphate (active vitamin B6) biosynthesis PdxA; InterPro IPR005255; KEGG: phe:Phep_3813 4-hydroxythreonine-4-phosphate dehydrogenase; PFAM: Pyridoxal phosphate (active vitamin B6) biosynthesis PdxA; PRIAM: 4-hydroxythreonine-4-phosphate dehydrogenase; SPTR: 4-hydroxythreonine-4-phosphate dehydrogenase; TIGRFAM: Pyridoxal phosphate (active vitamin B6) biosynthesis PdxA; IMG reference gene:2504772703; PFAM: Pyridoxal phosphate biosynthetic protein PdxA; TIGRFAM: 4-hydro [...] | Pyridoxine 5'-phosphate synthase; Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino- 2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate. | 0.908 |
| AEE51182.1 | ribB | Halhy_3323 | Halhy_5567 | 4-hydroxythreonine-4-phosphate dehydrogenase; COGs: COG1995 Pyridoxal phosphate biosynthesis protein; HAMAP: Pyridoxal phosphate (active vitamin B6) biosynthesis PdxA; InterPro IPR005255; KEGG: phe:Phep_3813 4-hydroxythreonine-4-phosphate dehydrogenase; PFAM: Pyridoxal phosphate (active vitamin B6) biosynthesis PdxA; PRIAM: 4-hydroxythreonine-4-phosphate dehydrogenase; SPTR: 4-hydroxythreonine-4-phosphate dehydrogenase; TIGRFAM: Pyridoxal phosphate (active vitamin B6) biosynthesis PdxA; IMG reference gene:2504772703; PFAM: Pyridoxal phosphate biosynthetic protein PdxA; TIGRFAM: 4-hydro [...] | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | 0.436 |
| AEE51182.1 | rsmA | Halhy_3323 | Halhy_3322 | 4-hydroxythreonine-4-phosphate dehydrogenase; COGs: COG1995 Pyridoxal phosphate biosynthesis protein; HAMAP: Pyridoxal phosphate (active vitamin B6) biosynthesis PdxA; InterPro IPR005255; KEGG: phe:Phep_3813 4-hydroxythreonine-4-phosphate dehydrogenase; PFAM: Pyridoxal phosphate (active vitamin B6) biosynthesis PdxA; PRIAM: 4-hydroxythreonine-4-phosphate dehydrogenase; SPTR: 4-hydroxythreonine-4-phosphate dehydrogenase; TIGRFAM: Pyridoxal phosphate (active vitamin B6) biosynthesis PdxA; IMG reference gene:2504772703; PFAM: Pyridoxal phosphate biosynthetic protein PdxA; TIGRFAM: 4-hydro [...] | Ribosomal RNA small subunit methyltransferase A; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. | 0.743 |
| AEE51182.1 | secF | Halhy_3323 | Halhy_6212 | 4-hydroxythreonine-4-phosphate dehydrogenase; COGs: COG1995 Pyridoxal phosphate biosynthesis protein; HAMAP: Pyridoxal phosphate (active vitamin B6) biosynthesis PdxA; InterPro IPR005255; KEGG: phe:Phep_3813 4-hydroxythreonine-4-phosphate dehydrogenase; PFAM: Pyridoxal phosphate (active vitamin B6) biosynthesis PdxA; PRIAM: 4-hydroxythreonine-4-phosphate dehydrogenase; SPTR: 4-hydroxythreonine-4-phosphate dehydrogenase; TIGRFAM: Pyridoxal phosphate (active vitamin B6) biosynthesis PdxA; IMG reference gene:2504772703; PFAM: Pyridoxal phosphate biosynthetic protein PdxA; TIGRFAM: 4-hydro [...] | Protein-export membrane protein SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA; Belongs to the SecD/SecF family. SecD subfamily. | 0.485 |
| AEE51182.1 | serC | Halhy_3323 | Halhy_3493 | 4-hydroxythreonine-4-phosphate dehydrogenase; COGs: COG1995 Pyridoxal phosphate biosynthesis protein; HAMAP: Pyridoxal phosphate (active vitamin B6) biosynthesis PdxA; InterPro IPR005255; KEGG: phe:Phep_3813 4-hydroxythreonine-4-phosphate dehydrogenase; PFAM: Pyridoxal phosphate (active vitamin B6) biosynthesis PdxA; PRIAM: 4-hydroxythreonine-4-phosphate dehydrogenase; SPTR: 4-hydroxythreonine-4-phosphate dehydrogenase; TIGRFAM: Pyridoxal phosphate (active vitamin B6) biosynthesis PdxA; IMG reference gene:2504772703; PFAM: Pyridoxal phosphate biosynthetic protein PdxA; TIGRFAM: 4-hydro [...] | Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. | 0.570 |
| AEE51182.1 | serC-2 | Halhy_3323 | Halhy_6497 | 4-hydroxythreonine-4-phosphate dehydrogenase; COGs: COG1995 Pyridoxal phosphate biosynthesis protein; HAMAP: Pyridoxal phosphate (active vitamin B6) biosynthesis PdxA; InterPro IPR005255; KEGG: phe:Phep_3813 4-hydroxythreonine-4-phosphate dehydrogenase; PFAM: Pyridoxal phosphate (active vitamin B6) biosynthesis PdxA; PRIAM: 4-hydroxythreonine-4-phosphate dehydrogenase; SPTR: 4-hydroxythreonine-4-phosphate dehydrogenase; TIGRFAM: Pyridoxal phosphate (active vitamin B6) biosynthesis PdxA; IMG reference gene:2504772703; PFAM: Pyridoxal phosphate biosynthetic protein PdxA; TIGRFAM: 4-hydro [...] | Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. | 0.570 |
| AEE51856.1 | AEE50985.1 | Halhy_4008 | Halhy_3123 | Protein of unknown function DUF164; COGs: COG1579 Zn-ribbon protein possibly nucleic acid-binding; InterPro IPR003743; KEGG: cpi:Cpin_6895 protein of unknown function DUF164; PFAM: Protein of unknown function DUF164; SPTR: Putative uncharacterized protein; IMG reference gene:2504773393; PFAM: Putative zinc ribbon domain. | Surface antigen (D15); COGs: COG4775 Outer membrane protein/protective antigen OMA87; InterPro IPR010827:IPR000184; KEGG: cpi:Cpin_1052 surface antigen variable number repeat protein; PFAM: Bacterial surface antigen (D15); Surface antigen variable number; SPTR: Bacterial surface antigen family protein; IMG reference gene:2504772503; PFAM: Surface antigen variable number repeat; TIGRFAM: outer membrane protein assembly complex, YaeT protein. | 0.725 |
| AEE51856.1 | AEE51182.1 | Halhy_4008 | Halhy_3323 | Protein of unknown function DUF164; COGs: COG1579 Zn-ribbon protein possibly nucleic acid-binding; InterPro IPR003743; KEGG: cpi:Cpin_6895 protein of unknown function DUF164; PFAM: Protein of unknown function DUF164; SPTR: Putative uncharacterized protein; IMG reference gene:2504773393; PFAM: Putative zinc ribbon domain. | 4-hydroxythreonine-4-phosphate dehydrogenase; COGs: COG1995 Pyridoxal phosphate biosynthesis protein; HAMAP: Pyridoxal phosphate (active vitamin B6) biosynthesis PdxA; InterPro IPR005255; KEGG: phe:Phep_3813 4-hydroxythreonine-4-phosphate dehydrogenase; PFAM: Pyridoxal phosphate (active vitamin B6) biosynthesis PdxA; PRIAM: 4-hydroxythreonine-4-phosphate dehydrogenase; SPTR: 4-hydroxythreonine-4-phosphate dehydrogenase; TIGRFAM: Pyridoxal phosphate (active vitamin B6) biosynthesis PdxA; IMG reference gene:2504772703; PFAM: Pyridoxal phosphate biosynthetic protein PdxA; TIGRFAM: 4-hydro [...] | 0.411 |
