Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AEE51203.1Rhomboid family protein; COGs: COG0705 membrane protein; InterPro IPR002610; KEGG: pdi:BDI_3604 rhomboid family protein; PFAM: Peptidase S54, rhomboid; SPTR: Rhomboid family protein; IMG reference gene:2504772724; PFAM: Rhomboid family. (324 aa)    
Predicted Functional Partners:
AEE51204.1
Endonuclease/exonuclease/phosphatase; COGs: COG3568 Metal-dependent hydrolase; InterPro IPR005135; KEGG: cpi:Cpin_0858 endonuclease/exonuclease/phosphatase; PFAM: Endonuclease/exonuclease/phosphatase; SPTR: Endonuclease/exonuclease/phosphatase; IMG reference gene:2504772725; PFAM: Endonuclease/Exonuclease/phosphatase family.
 
     0.832
cysS
COGs: COG0215 Cysteinyl-tRNA synthetase; InterPro IPR002308:IPR015803:IPR015273; KEGG: gfo:GFO_2741 cysteinyl-tRNA synthetase; PFAM: Cysteinyl-tRNA synthetase, class Ia, N-terminal; Cysteinyl-tRNA synthetase, class Ia, DALR; PRIAM: Cysteine--tRNA ligase; SPTR: Cysteinyl-tRNA synthetase; TIGRFAM: Cysteinyl-tRNA synthetase, class Ia; IMG reference gene:2504772726; PFAM: tRNA synthetases class I (C) catalytic domain; DALR domain; TIGRFAM: cysteinyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family.
       0.704
AEE51202.1
Rhomboid family protein; COGs: COG0705 membrane protein; InterPro IPR002610; KEGG: rbi:RB2501_01655 hypothetical protein; PFAM: Peptidase S54, rhomboid; SPTR: Putative uncharacterized protein; IMG reference gene:2504772723; PFAM: Rhomboid family.
 
    
0.671
AEE53389.1
InterPro IPR019734; KEGG: dfe:Dfer_3815 tetratricopeptide domain protein; SPTR: TPR repeat-containing protein; IMG reference gene:2504774963.
 
     0.586
AEE50796.1
InterPro IPR003369; KEGG: cpi:Cpin_1332 twin-arginine translocation protein, TatA/E family subunit; PFAM: Bacterial sec-independent translocation protein mttA/Hcf106; SPTR: Sec-independent protein translocase protein tatA/E homolog; IMG reference gene:2504772306; PFAM: mttA/Hcf106 family; TIGRFAM: twin arginine-targeting protein translocase, TatA/E family.
  
 
 0.581
mutL
DNA mismatch repair protein mutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
 
    0.579
AEE52629.1
KEGG: cpi:Cpin_1183 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504774189.
 
     0.576
AEE52129.1
KEGG: sli:Slin_1298 hypothetical protein; SPTR: Putative outer membrane protein; IMG reference gene:2504773671.
  
     0.523
AEE52016.1
KEGG: phe:Phep_0010 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504773556.
  
     0.519
AEE49871.1
KEGG: cpi:Cpin_6946 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504771352.
 
     0.516
Your Current Organism:
Haliscomenobacter hydrossis
NCBI taxonomy Id: 760192
Other names: H. hydrossis DSM 1100, Haliscomenobacter hydrossis DSM 1100
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.