| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AEE47924.1 | AEE51303.1 | Halhy_0010 | Halhy_3447 | COGs: COG3278 Cbb3-type cytochrome oxidase subunit 1; InterPro IPR000883:IPR003468:IPR004677; KEGG: mtt:Ftrac_1616 cytochrome c oxidase, cbb3-type, subunit I; PFAM: Cytochrome C oxidase, monohaem subunit/FixO; Cytochrome c oxidase, subunit I; PRIAM: Cytochrome-c oxidase; SPTR: Cytochrome c oxidase, cbb3-type; TIGRFAM: Cytochrome c oxidase cbb3-type, subunit I; Cytochrome C oxidase, monohaem subunit/FixO; IMG reference gene:2504769359; PFAM: Cytochrome C oxidase, mono-heme subunit/FixO; Cytochrome C and Quinol oxidase polypeptide I; TIGRFAM: cytochrome c oxidase, cbb3-type, subunit II; [...] | COGs: COG0635 Coproporphyrinogen III oxidase and related Fe-S oxidoreductase; InterPro IPR006638:IPR004558:IPR007197:IPR010723; KEGG: cpi:Cpin_0687 coproporphyrinogen III oxidase; PFAM: HemN, C-terminal; Radical SAM; SMART: Elongator protein 3/MiaB/NifB; SPTR: Oxygen-independent coproporphyrinogen III oxidase; TIGRFAM: Oxygen-independent coproporphyrinogen III oxidase HemN; IMG reference gene:2504772828; PFAM: Radical SAM superfamily; HemN C-terminal region; TIGRFAM: oxygen-independent coproporphyrinogen III oxidase; Belongs to the anaerobic coproporphyrinogen-III oxidase family. | 0.948 |
| AEE47924.1 | AEE51305.1 | Halhy_0010 | Halhy_3449 | COGs: COG3278 Cbb3-type cytochrome oxidase subunit 1; InterPro IPR000883:IPR003468:IPR004677; KEGG: mtt:Ftrac_1616 cytochrome c oxidase, cbb3-type, subunit I; PFAM: Cytochrome C oxidase, monohaem subunit/FixO; Cytochrome c oxidase, subunit I; PRIAM: Cytochrome-c oxidase; SPTR: Cytochrome c oxidase, cbb3-type; TIGRFAM: Cytochrome c oxidase cbb3-type, subunit I; Cytochrome C oxidase, monohaem subunit/FixO; IMG reference gene:2504769359; PFAM: Cytochrome C oxidase, mono-heme subunit/FixO; Cytochrome C and Quinol oxidase polypeptide I; TIGRFAM: cytochrome c oxidase, cbb3-type, subunit II; [...] | Transcriptional regulator, BadM/Rrf2 family; COGs: COG1959 transcriptional regulator protein; InterPro IPR000944; KEGG: fjo:Fjoh_1888 BadM/Rrf2 family transcriptional regulator; PFAM: Transcriptional regulator, Rrf2; SPTR: Transcriptional regulator, BadM/Rrf2 family; TIGRFAM: Transcriptional regulator, Rrf2; IMG reference gene:2504772830; PFAM: Transcriptional regulator; TIGRFAM: Rrf2 family protein. | 0.672 |
| AEE47924.1 | AEE53314.1 | Halhy_0010 | Halhy_5489 | COGs: COG3278 Cbb3-type cytochrome oxidase subunit 1; InterPro IPR000883:IPR003468:IPR004677; KEGG: mtt:Ftrac_1616 cytochrome c oxidase, cbb3-type, subunit I; PFAM: Cytochrome C oxidase, monohaem subunit/FixO; Cytochrome c oxidase, subunit I; PRIAM: Cytochrome-c oxidase; SPTR: Cytochrome c oxidase, cbb3-type; TIGRFAM: Cytochrome c oxidase cbb3-type, subunit I; Cytochrome C oxidase, monohaem subunit/FixO; IMG reference gene:2504769359; PFAM: Cytochrome C oxidase, mono-heme subunit/FixO; Cytochrome C and Quinol oxidase polypeptide I; TIGRFAM: cytochrome c oxidase, cbb3-type, subunit II; [...] | Transcriptional regulator, BadM/Rrf2 family; COGs: COG1959 transcriptional regulator protein; InterPro IPR000944; KEGG: dfe:Dfer_2184 transcriptional regulator, BadM/Rrf2 family; PFAM: Transcriptional regulator, Rrf2; SPTR: Possible transcription regulator; TIGRFAM: Transcriptional regulator, Rrf2; IMG reference gene:2504774887; PFAM: Transcriptional regulator; TIGRFAM: Rrf2 family protein. | 0.672 |
| AEE48184.1 | AEE49237.1 | Halhy_0272 | Halhy_1342 | Co-chaperone Hsc20; InterPro IPR001623:IPR009073:IPR004640; KEGG: phe:Phep_3175 co-chaperone Hsc20; PFAM: Heat shock protein DnaJ, N-terminal; Heat shock cognate protein B, C-terminal oligomerisation; SPTR: Co-chaperone Hsc20; TIGRFAM: Co-chaperone Hsc20; IMG reference gene:2504769625; PFAM: DnaJ domain; HSCB C-terminal oligomerisation domain; TIGRFAM: Fe-S protein assembly co-chaperone HscB. | FeS cluster assembly scaffold IscU; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. | 0.978 |
| AEE48184.1 | AEE51305.1 | Halhy_0272 | Halhy_3449 | Co-chaperone Hsc20; InterPro IPR001623:IPR009073:IPR004640; KEGG: phe:Phep_3175 co-chaperone Hsc20; PFAM: Heat shock protein DnaJ, N-terminal; Heat shock cognate protein B, C-terminal oligomerisation; SPTR: Co-chaperone Hsc20; TIGRFAM: Co-chaperone Hsc20; IMG reference gene:2504769625; PFAM: DnaJ domain; HSCB C-terminal oligomerisation domain; TIGRFAM: Fe-S protein assembly co-chaperone HscB. | Transcriptional regulator, BadM/Rrf2 family; COGs: COG1959 transcriptional regulator protein; InterPro IPR000944; KEGG: fjo:Fjoh_1888 BadM/Rrf2 family transcriptional regulator; PFAM: Transcriptional regulator, Rrf2; SPTR: Transcriptional regulator, BadM/Rrf2 family; TIGRFAM: Transcriptional regulator, Rrf2; IMG reference gene:2504772830; PFAM: Transcriptional regulator; TIGRFAM: Rrf2 family protein. | 0.432 |
| AEE48184.1 | AEE53314.1 | Halhy_0272 | Halhy_5489 | Co-chaperone Hsc20; InterPro IPR001623:IPR009073:IPR004640; KEGG: phe:Phep_3175 co-chaperone Hsc20; PFAM: Heat shock protein DnaJ, N-terminal; Heat shock cognate protein B, C-terminal oligomerisation; SPTR: Co-chaperone Hsc20; TIGRFAM: Co-chaperone Hsc20; IMG reference gene:2504769625; PFAM: DnaJ domain; HSCB C-terminal oligomerisation domain; TIGRFAM: Fe-S protein assembly co-chaperone HscB. | Transcriptional regulator, BadM/Rrf2 family; COGs: COG1959 transcriptional regulator protein; InterPro IPR000944; KEGG: dfe:Dfer_2184 transcriptional regulator, BadM/Rrf2 family; PFAM: Transcriptional regulator, Rrf2; SPTR: Possible transcription regulator; TIGRFAM: Transcriptional regulator, Rrf2; IMG reference gene:2504774887; PFAM: Transcriptional regulator; TIGRFAM: Rrf2 family protein. | 0.432 |
| AEE48184.1 | AEE53631.1 | Halhy_0272 | Halhy_5808 | Co-chaperone Hsc20; InterPro IPR001623:IPR009073:IPR004640; KEGG: phe:Phep_3175 co-chaperone Hsc20; PFAM: Heat shock protein DnaJ, N-terminal; Heat shock cognate protein B, C-terminal oligomerisation; SPTR: Co-chaperone Hsc20; TIGRFAM: Co-chaperone Hsc20; IMG reference gene:2504769625; PFAM: DnaJ domain; HSCB C-terminal oligomerisation domain; TIGRFAM: Fe-S protein assembly co-chaperone HscB. | COGs: COG1104 Cysteine sulfinate desulfinase/cysteine desulfurase; InterPro IPR000192; KEGG: cpi:Cpin_1845 cysteine desulfurase; PFAM: Aminotransferase, class V/Cysteine desulfurase; PRIAM: Cysteine desulfurase; SPTR: Cysteine desulfurase; IMG reference gene:2504775206; PFAM: Aminotransferase class-V. | 0.727 |
| AEE48184.1 | AEE54184.1 | Halhy_0272 | Halhy_6365 | Co-chaperone Hsc20; InterPro IPR001623:IPR009073:IPR004640; KEGG: phe:Phep_3175 co-chaperone Hsc20; PFAM: Heat shock protein DnaJ, N-terminal; Heat shock cognate protein B, C-terminal oligomerisation; SPTR: Co-chaperone Hsc20; TIGRFAM: Co-chaperone Hsc20; IMG reference gene:2504769625; PFAM: DnaJ domain; HSCB C-terminal oligomerisation domain; TIGRFAM: Fe-S protein assembly co-chaperone HscB. | SUF system FeS assembly protein, NifU family; COGs: COG0822 NifU homolog involved in Fe-S cluster formation; InterPro IPR011341:IPR002871; KEGG: tmz:Tmz1t_1895 SUF system FeS assembly protein, NifU family; PFAM: NIF system FeS cluster assembly, NifU, N-terminal; SPTR: SUF system FeS assembly protein, NifU family; TIGRFAM: SUF system FeS cluster assembly, SufU scaffold; IMG reference gene:2504775773; PFAM: NifU-like N terminal domain; TIGRFAM: SUF system FeS assembly protein, NifU family. | 0.925 |
| AEE48184.1 | iscS | Halhy_0272 | Halhy_1343 | Co-chaperone Hsc20; InterPro IPR001623:IPR009073:IPR004640; KEGG: phe:Phep_3175 co-chaperone Hsc20; PFAM: Heat shock protein DnaJ, N-terminal; Heat shock cognate protein B, C-terminal oligomerisation; SPTR: Co-chaperone Hsc20; TIGRFAM: Co-chaperone Hsc20; IMG reference gene:2504769625; PFAM: DnaJ domain; HSCB C-terminal oligomerisation domain; TIGRFAM: Fe-S protein assembly co-chaperone HscB. | Cysteine desulfurase; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily. | 0.880 |
| AEE49237.1 | AEE48184.1 | Halhy_1342 | Halhy_0272 | FeS cluster assembly scaffold IscU; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. | Co-chaperone Hsc20; InterPro IPR001623:IPR009073:IPR004640; KEGG: phe:Phep_3175 co-chaperone Hsc20; PFAM: Heat shock protein DnaJ, N-terminal; Heat shock cognate protein B, C-terminal oligomerisation; SPTR: Co-chaperone Hsc20; TIGRFAM: Co-chaperone Hsc20; IMG reference gene:2504769625; PFAM: DnaJ domain; HSCB C-terminal oligomerisation domain; TIGRFAM: Fe-S protein assembly co-chaperone HscB. | 0.978 |
| AEE49237.1 | AEE51305.1 | Halhy_1342 | Halhy_3449 | FeS cluster assembly scaffold IscU; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. | Transcriptional regulator, BadM/Rrf2 family; COGs: COG1959 transcriptional regulator protein; InterPro IPR000944; KEGG: fjo:Fjoh_1888 BadM/Rrf2 family transcriptional regulator; PFAM: Transcriptional regulator, Rrf2; SPTR: Transcriptional regulator, BadM/Rrf2 family; TIGRFAM: Transcriptional regulator, Rrf2; IMG reference gene:2504772830; PFAM: Transcriptional regulator; TIGRFAM: Rrf2 family protein. | 0.474 |
| AEE49237.1 | AEE53314.1 | Halhy_1342 | Halhy_5489 | FeS cluster assembly scaffold IscU; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. | Transcriptional regulator, BadM/Rrf2 family; COGs: COG1959 transcriptional regulator protein; InterPro IPR000944; KEGG: dfe:Dfer_2184 transcriptional regulator, BadM/Rrf2 family; PFAM: Transcriptional regulator, Rrf2; SPTR: Possible transcription regulator; TIGRFAM: Transcriptional regulator, Rrf2; IMG reference gene:2504774887; PFAM: Transcriptional regulator; TIGRFAM: Rrf2 family protein. | 0.474 |
| AEE49237.1 | AEE53631.1 | Halhy_1342 | Halhy_5808 | FeS cluster assembly scaffold IscU; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. | COGs: COG1104 Cysteine sulfinate desulfinase/cysteine desulfurase; InterPro IPR000192; KEGG: cpi:Cpin_1845 cysteine desulfurase; PFAM: Aminotransferase, class V/Cysteine desulfurase; PRIAM: Cysteine desulfurase; SPTR: Cysteine desulfurase; IMG reference gene:2504775206; PFAM: Aminotransferase class-V. | 0.983 |
| AEE49237.1 | iscS | Halhy_1342 | Halhy_1343 | FeS cluster assembly scaffold IscU; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. | Cysteine desulfurase; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily. | 0.994 |
| AEE51303.1 | AEE47924.1 | Halhy_3447 | Halhy_0010 | COGs: COG0635 Coproporphyrinogen III oxidase and related Fe-S oxidoreductase; InterPro IPR006638:IPR004558:IPR007197:IPR010723; KEGG: cpi:Cpin_0687 coproporphyrinogen III oxidase; PFAM: HemN, C-terminal; Radical SAM; SMART: Elongator protein 3/MiaB/NifB; SPTR: Oxygen-independent coproporphyrinogen III oxidase; TIGRFAM: Oxygen-independent coproporphyrinogen III oxidase HemN; IMG reference gene:2504772828; PFAM: Radical SAM superfamily; HemN C-terminal region; TIGRFAM: oxygen-independent coproporphyrinogen III oxidase; Belongs to the anaerobic coproporphyrinogen-III oxidase family. | COGs: COG3278 Cbb3-type cytochrome oxidase subunit 1; InterPro IPR000883:IPR003468:IPR004677; KEGG: mtt:Ftrac_1616 cytochrome c oxidase, cbb3-type, subunit I; PFAM: Cytochrome C oxidase, monohaem subunit/FixO; Cytochrome c oxidase, subunit I; PRIAM: Cytochrome-c oxidase; SPTR: Cytochrome c oxidase, cbb3-type; TIGRFAM: Cytochrome c oxidase cbb3-type, subunit I; Cytochrome C oxidase, monohaem subunit/FixO; IMG reference gene:2504769359; PFAM: Cytochrome C oxidase, mono-heme subunit/FixO; Cytochrome C and Quinol oxidase polypeptide I; TIGRFAM: cytochrome c oxidase, cbb3-type, subunit II; [...] | 0.948 |
| AEE51303.1 | AEE51304.1 | Halhy_3447 | Halhy_3448 | COGs: COG0635 Coproporphyrinogen III oxidase and related Fe-S oxidoreductase; InterPro IPR006638:IPR004558:IPR007197:IPR010723; KEGG: cpi:Cpin_0687 coproporphyrinogen III oxidase; PFAM: HemN, C-terminal; Radical SAM; SMART: Elongator protein 3/MiaB/NifB; SPTR: Oxygen-independent coproporphyrinogen III oxidase; TIGRFAM: Oxygen-independent coproporphyrinogen III oxidase HemN; IMG reference gene:2504772828; PFAM: Radical SAM superfamily; HemN C-terminal region; TIGRFAM: oxygen-independent coproporphyrinogen III oxidase; Belongs to the anaerobic coproporphyrinogen-III oxidase family. | Methyltransferase type 12; InterPro IPR013217; KEGG: psl:Psta_4430 methyltransferase type 11; PFAM: Methyltransferase type 12; SPTR: Putative uncharacterized protein; IMG reference gene:2504772829; PFAM: Methyltransferase domain. | 0.513 |
| AEE51303.1 | AEE51305.1 | Halhy_3447 | Halhy_3449 | COGs: COG0635 Coproporphyrinogen III oxidase and related Fe-S oxidoreductase; InterPro IPR006638:IPR004558:IPR007197:IPR010723; KEGG: cpi:Cpin_0687 coproporphyrinogen III oxidase; PFAM: HemN, C-terminal; Radical SAM; SMART: Elongator protein 3/MiaB/NifB; SPTR: Oxygen-independent coproporphyrinogen III oxidase; TIGRFAM: Oxygen-independent coproporphyrinogen III oxidase HemN; IMG reference gene:2504772828; PFAM: Radical SAM superfamily; HemN C-terminal region; TIGRFAM: oxygen-independent coproporphyrinogen III oxidase; Belongs to the anaerobic coproporphyrinogen-III oxidase family. | Transcriptional regulator, BadM/Rrf2 family; COGs: COG1959 transcriptional regulator protein; InterPro IPR000944; KEGG: fjo:Fjoh_1888 BadM/Rrf2 family transcriptional regulator; PFAM: Transcriptional regulator, Rrf2; SPTR: Transcriptional regulator, BadM/Rrf2 family; TIGRFAM: Transcriptional regulator, Rrf2; IMG reference gene:2504772830; PFAM: Transcriptional regulator; TIGRFAM: Rrf2 family protein. | 0.574 |
| AEE51304.1 | AEE51303.1 | Halhy_3448 | Halhy_3447 | Methyltransferase type 12; InterPro IPR013217; KEGG: psl:Psta_4430 methyltransferase type 11; PFAM: Methyltransferase type 12; SPTR: Putative uncharacterized protein; IMG reference gene:2504772829; PFAM: Methyltransferase domain. | COGs: COG0635 Coproporphyrinogen III oxidase and related Fe-S oxidoreductase; InterPro IPR006638:IPR004558:IPR007197:IPR010723; KEGG: cpi:Cpin_0687 coproporphyrinogen III oxidase; PFAM: HemN, C-terminal; Radical SAM; SMART: Elongator protein 3/MiaB/NifB; SPTR: Oxygen-independent coproporphyrinogen III oxidase; TIGRFAM: Oxygen-independent coproporphyrinogen III oxidase HemN; IMG reference gene:2504772828; PFAM: Radical SAM superfamily; HemN C-terminal region; TIGRFAM: oxygen-independent coproporphyrinogen III oxidase; Belongs to the anaerobic coproporphyrinogen-III oxidase family. | 0.513 |
| AEE51304.1 | AEE51305.1 | Halhy_3448 | Halhy_3449 | Methyltransferase type 12; InterPro IPR013217; KEGG: psl:Psta_4430 methyltransferase type 11; PFAM: Methyltransferase type 12; SPTR: Putative uncharacterized protein; IMG reference gene:2504772829; PFAM: Methyltransferase domain. | Transcriptional regulator, BadM/Rrf2 family; COGs: COG1959 transcriptional regulator protein; InterPro IPR000944; KEGG: fjo:Fjoh_1888 BadM/Rrf2 family transcriptional regulator; PFAM: Transcriptional regulator, Rrf2; SPTR: Transcriptional regulator, BadM/Rrf2 family; TIGRFAM: Transcriptional regulator, Rrf2; IMG reference gene:2504772830; PFAM: Transcriptional regulator; TIGRFAM: Rrf2 family protein. | 0.773 |
| AEE51304.1 | AEE51306.1 | Halhy_3448 | Halhy_3450 | Methyltransferase type 12; InterPro IPR013217; KEGG: psl:Psta_4430 methyltransferase type 11; PFAM: Methyltransferase type 12; SPTR: Putative uncharacterized protein; IMG reference gene:2504772829; PFAM: Methyltransferase domain. | Protein of unknown function DUF187; COGs: COG1649 conserved hypothetical protein; InterPro IPR003790; KEGG: cpi:Cpin_0723 protein of unknown function DUF187; PFAM: Protein of unknown function DUF187; SPTR: Putative uncharacterized protein; IMG reference gene:2504772831; PFAM: Uncharacterised BCR, COG1649. | 0.526 |