Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AEE51373.1Two component transcriptional regulator, LytTR family; COGs: COG3279 Response regulator of the LytR/AlgR family; InterPro IPR001789:IPR007492; KEGG: mtt:Ftrac_0265 two component transcriptional regulator, LytTR family; PFAM: LytTr DNA-binding region; Signal transduction response regulator, receiver region; SMART: Signal transduction response regulator, receiver region; SPTR: Sensory transduction regulatory protein; IMG reference gene:2504772899; PFAM: Response regulator receiver domain; LytTr DNA-binding domain. (241 aa)    
Predicted Functional Partners:
AEE51916.1
COGs: COG3920 Signal transduction histidine kinase; InterPro IPR011495:IPR003594; KEGG: sli:Slin_2255 signal transduction histidine kinase; PFAM: Signal transduction histidine kinase, subgroup 2, dimerisation and phosphoacceptor region; ATP-binding region, ATPase-like; SMART: ATP-binding region, ATPase-like; SPTR: Sensory box histidine kinase; IMG reference gene:2504773454; PFAM: Histidine kinase; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase.
  
     0.734
AEE52692.1
COGs: COG3920 Signal transduction histidine kinase; InterPro IPR019734:IPR001440:IPR011495:IPR003594; KEGG: sli:Slin_3428 signal transduction histidine kinase; PFAM: Signal transduction histidine kinase, subgroup 2, dimerisation and phosphoacceptor region; Tetratricopeptide TPR-1; ATP-binding region, ATPase-like; SPTR: Signal transduction histidine kinase; IMG reference gene:2504774257; PFAM: Histidine kinase; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase.
  
     0.734
AEE51374.1
ATP-binding region ATPase domain protein; COGs: COG0642 Signal transduction histidine kinase; InterProIPR019734:IPR003661:IPR003594:IPR013105:IPR 001440; KEGG: mtt:Ftrac_1355 histidine kinase; PFAM: ATP-binding region, ATPase-like; Tetratricopeptide TPR2; Tetratricopeptide TPR-1; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; SMART: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; Tetratricopeptide repeat; SPTR: Histidine kinase; IMG reference gene:2504772900; PFAM: Histidine [...]
 
    0.723
AEE54018.1
COGs: COG3920 Signal transduction histidine kinase; InterPro IPR001440:IPR011495:IPR003594:IPR019734; KEGG: cyc:PCC7424_4563 signal transduction histidine kinase; PFAM: Signal transduction histidine kinase, subgroup 2, dimerisation and phosphoacceptor region; Tetratricopeptide TPR-1; ATP-binding region, ATPase-like; SMART: ATP-binding region, ATPase-like; Tetratricopeptide repeat; SPTR: Sensory box histidine kinase; IMG reference gene:2504775604; PFAM: Histidine kinase; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Tetratricopeptide repeat.
  
     0.720
AEE53408.1
COGs: COG3920 Signal transduction histidine kinase; InterPro IPR003594:IPR011495; KEGG: cat:CA2559_11268 histidine kinase sensor protein; PFAM: Signal transduction histidine kinase, subgroup 2, dimerisation and phosphoacceptor region; ATP-binding region, ATPase-like; SMART: ATP-binding region, ATPase-like; SPTR: Multisensor signal transduction histidine kinase; IMG reference gene:2504774982; PFAM: Histidine kinase; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase.
  
     0.711
AEE51372.1
Peptidase S41; InterPro IPR005151; KEGG: cpi:Cpin_5002 peptidase S41; PFAM: Peptidase S41; SPTR: Peptidase, S41 family; IMG reference gene:2504772898; PFAM: Peptidase family S41.
       0.510
AEE48949.1
Two component transcriptional regulator, LytTR family; COGs: COG3279 Response regulator of the LytR/AlgR family; InterPro IPR001789:IPR007492; KEGG: dfe:Dfer_1279 two component transcriptional regulator, LytTR family; PFAM: Signal transduction response regulator, receiver region; LytTr DNA-binding region; SMART: Signal transduction response regulator, receiver region; SPTR: Two component transcriptional regulator, LytTR family; IMG reference gene:2504770411; PFAM: Response regulator receiver domain; LytTr DNA-binding domain.
  
     0.500
AEE49533.1
Two component transcriptional regulator, LytTR family; COGs: COG3279 Response regulator of the LytR/AlgR family; InterPro IPR001789:IPR007492; KEGG: dfe:Dfer_1279 two component transcriptional regulator, LytTR family; PFAM: Signal transduction response regulator, receiver region; LytTr DNA-binding region; SMART: Signal transduction response regulator, receiver region; SPTR: Two component transcriptional regulator, LytTR family; IMG reference gene:2504771005; PFAM: Response regulator receiver domain; LytTr DNA-binding domain.
  
     0.440
AEE51074.1
Putative signal transduction histidine kinase; COGs: COG3275 Putative regulator of cell autolysis; InterPro IPR010559; KEGG: phe:Phep_0216 histidine kinase internal region; PFAM: Signal transduction histidine kinase, internal region; SPTR: Putative transmembrane protein; IMG reference gene:2504772594; PFAM: Histidine kinase.
  
   0.424
AEE49194.1
Two component transcriptional regulator, LytTR family; COGs: COG3279 Response regulator of the LytR/AlgR family; InterPro IPR001789:IPR007492; KEGG: rbi:RB2501_05790 LytTr DNA-binding domain family protein; PFAM: Signal transduction response regulator, receiver region; LytTr DNA-binding region; SMART: Signal transduction response regulator, receiver region; SPTR: LytTr DNA-binding domain family protein; IMG reference gene:2504770660; PFAM: Response regulator receiver domain; LytTr DNA-binding domain.
  
     0.415
Your Current Organism:
Haliscomenobacter hydrossis
NCBI taxonomy Id: 760192
Other names: H. hydrossis DSM 1100, Haliscomenobacter hydrossis DSM 1100
Server load: low (18%) [HD]