Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AEE51405.1InterPro IPR018004; KEGG: gur:Gura_3302 hypothetical protein; PFAM: KilA, N-terminal/APSES-type HTH DNA-binding domain; SPTR: Putative uncharacterized protein; IMG reference gene:2504772931; PFAM: KilA-N domain. (148 aa)    
Predicted Functional Partners:
AEE51406.1
KEGG: phe:Phep_3068 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504772932; PFAM: Protein of unknown function (DUF2851).
       0.705
AEE51407.1
Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.
       0.465
AEE51408.1
Capsule synthesis protein, CapA; COGs: COG2843 Putative protein of poly-gamma-glutamate biosynthesis (capsule formation); InterPro IPR019079; KEGG: capsule synthesis protein, CapA; PFAM: Capsule synthesis protein, CapA; SPTR: Putative uncharacterized protein; IMG reference gene:2504772934; PFAM: Bacterial capsule synthesis protein PGA_cap.
       0.465
AEE50127.1
Protein of unknown function DUF1016; COGs: COG4804 conserved hypothetical protein; InterPro IPR009362; KEGG: nde:NIDE0138 hypothetical protein; PFAM: Protein of unknown function DUF1016; SPTR: Protein of hypothetical function DUF1016; IMG reference gene:2504771614; PFAM: Protein of unknown function (DUF1016).
 
     0.433
AEE49835.1
ATPase; COGs: COG1373 ATPase (AAA+ superfamily); KEGG: ppn:Palpr_1255 ATPase; SPTR: ATPase; IMG reference gene:2504771311.
  
     0.407
AEE51409.1
Penicillin-binding protein 2; COGs: COG0768 Cell division protein FtsI/penicillin-binding protein 2; InterPro IPR017790:IPR005311:IPR001460; KEGG: aas:Aasi_0246 hypothetical protein; PFAM: Penicillin-binding protein, transpeptidase; Penicillin-binding protein, dimerisation domain; PRIAM: Peptidoglycan glycosyltransferase; SPTR: Penicillin-binding protein 2; TIGRFAM: Penicillin-binding protein 2; IMG reference gene:2504772935; PFAM: Penicillin binding protein transpeptidase domain; Penicillin-binding Protein dimerisation domain; TIGRFAM: penicillin-binding protein 2.
       0.402
AEE48675.1
Death-on-curing family protein; COGs: COG3943 Virulence protein; InterPro IPR003812:IPR006440; KEGG: noc:Noc_1805 death-on-curing protein; PFAM: Filamentation induced by cAMP/death on curing, related; SPTR: Virulence protein; TIGRFAM: Death-on-curing protein; IMG reference gene:2504770127; PFAM: Fic/DOC family; TIGRFAM: death-on-curing family protein.
 
     0.401
Your Current Organism:
Haliscomenobacter hydrossis
NCBI taxonomy Id: 760192
Other names: H. hydrossis DSM 1100, Haliscomenobacter hydrossis DSM 1100
Server load: low (10%) [HD]