| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AEE48004.1 | AEE51408.1 | Halhy_0091 | Halhy_3553 | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | Capsule synthesis protein, CapA; COGs: COG2843 Putative protein of poly-gamma-glutamate biosynthesis (capsule formation); InterPro IPR019079; KEGG: capsule synthesis protein, CapA; PFAM: Capsule synthesis protein, CapA; SPTR: Putative uncharacterized protein; IMG reference gene:2504772934; PFAM: Bacterial capsule synthesis protein PGA_cap. | 0.701 |
| AEE51405.1 | AEE51406.1 | Halhy_3550 | Halhy_3551 | InterPro IPR018004; KEGG: gur:Gura_3302 hypothetical protein; PFAM: KilA, N-terminal/APSES-type HTH DNA-binding domain; SPTR: Putative uncharacterized protein; IMG reference gene:2504772931; PFAM: KilA-N domain. | KEGG: phe:Phep_3068 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504772932; PFAM: Protein of unknown function (DUF2851). | 0.705 |
| AEE51405.1 | AEE51407.1 | Halhy_3550 | Halhy_3552 | InterPro IPR018004; KEGG: gur:Gura_3302 hypothetical protein; PFAM: KilA, N-terminal/APSES-type HTH DNA-binding domain; SPTR: Putative uncharacterized protein; IMG reference gene:2504772931; PFAM: KilA-N domain. | Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | 0.465 |
| AEE51405.1 | AEE51408.1 | Halhy_3550 | Halhy_3553 | InterPro IPR018004; KEGG: gur:Gura_3302 hypothetical protein; PFAM: KilA, N-terminal/APSES-type HTH DNA-binding domain; SPTR: Putative uncharacterized protein; IMG reference gene:2504772931; PFAM: KilA-N domain. | Capsule synthesis protein, CapA; COGs: COG2843 Putative protein of poly-gamma-glutamate biosynthesis (capsule formation); InterPro IPR019079; KEGG: capsule synthesis protein, CapA; PFAM: Capsule synthesis protein, CapA; SPTR: Putative uncharacterized protein; IMG reference gene:2504772934; PFAM: Bacterial capsule synthesis protein PGA_cap. | 0.465 |
| AEE51405.1 | AEE51409.1 | Halhy_3550 | Halhy_3554 | InterPro IPR018004; KEGG: gur:Gura_3302 hypothetical protein; PFAM: KilA, N-terminal/APSES-type HTH DNA-binding domain; SPTR: Putative uncharacterized protein; IMG reference gene:2504772931; PFAM: KilA-N domain. | Penicillin-binding protein 2; COGs: COG0768 Cell division protein FtsI/penicillin-binding protein 2; InterPro IPR017790:IPR005311:IPR001460; KEGG: aas:Aasi_0246 hypothetical protein; PFAM: Penicillin-binding protein, transpeptidase; Penicillin-binding protein, dimerisation domain; PRIAM: Peptidoglycan glycosyltransferase; SPTR: Penicillin-binding protein 2; TIGRFAM: Penicillin-binding protein 2; IMG reference gene:2504772935; PFAM: Penicillin binding protein transpeptidase domain; Penicillin-binding Protein dimerisation domain; TIGRFAM: penicillin-binding protein 2. | 0.402 |
| AEE51406.1 | AEE51405.1 | Halhy_3551 | Halhy_3550 | KEGG: phe:Phep_3068 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504772932; PFAM: Protein of unknown function (DUF2851). | InterPro IPR018004; KEGG: gur:Gura_3302 hypothetical protein; PFAM: KilA, N-terminal/APSES-type HTH DNA-binding domain; SPTR: Putative uncharacterized protein; IMG reference gene:2504772931; PFAM: KilA-N domain. | 0.705 |
| AEE51406.1 | AEE51407.1 | Halhy_3551 | Halhy_3552 | KEGG: phe:Phep_3068 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504772932; PFAM: Protein of unknown function (DUF2851). | Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | 0.505 |
| AEE51406.1 | AEE51408.1 | Halhy_3551 | Halhy_3553 | KEGG: phe:Phep_3068 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504772932; PFAM: Protein of unknown function (DUF2851). | Capsule synthesis protein, CapA; COGs: COG2843 Putative protein of poly-gamma-glutamate biosynthesis (capsule formation); InterPro IPR019079; KEGG: capsule synthesis protein, CapA; PFAM: Capsule synthesis protein, CapA; SPTR: Putative uncharacterized protein; IMG reference gene:2504772934; PFAM: Bacterial capsule synthesis protein PGA_cap. | 0.505 |
| AEE51406.1 | AEE51409.1 | Halhy_3551 | Halhy_3554 | KEGG: phe:Phep_3068 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504772932; PFAM: Protein of unknown function (DUF2851). | Penicillin-binding protein 2; COGs: COG0768 Cell division protein FtsI/penicillin-binding protein 2; InterPro IPR017790:IPR005311:IPR001460; KEGG: aas:Aasi_0246 hypothetical protein; PFAM: Penicillin-binding protein, transpeptidase; Penicillin-binding protein, dimerisation domain; PRIAM: Peptidoglycan glycosyltransferase; SPTR: Penicillin-binding protein 2; TIGRFAM: Penicillin-binding protein 2; IMG reference gene:2504772935; PFAM: Penicillin binding protein transpeptidase domain; Penicillin-binding Protein dimerisation domain; TIGRFAM: penicillin-binding protein 2. | 0.434 |
| AEE51406.1 | AEE51410.1 | Halhy_3551 | Halhy_3555 | KEGG: phe:Phep_3068 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504772932; PFAM: Protein of unknown function (DUF2851). | KEGG: phe:Phep_0806 rod shape-determining protein MreD; SPTR: Rod shape-determining protein MreD; IMG reference gene:2504772936. | 0.487 |
| AEE51406.1 | AEE51411.1 | Halhy_3551 | Halhy_3556 | KEGG: phe:Phep_3068 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504772932; PFAM: Protein of unknown function (DUF2851). | COGs: COG1792 Cell shape-determining protein; InterPro IPR007221; KEGG: zpr:ZPR_0660 rod shape-determining protein MreC; PFAM: Rod shape-determining protein MreC; SPTR: Rod shape-determining protein MreC; IMG reference gene:2504772937; PFAM: rod shape-determining protein MreC; TIGRFAM: rod shape-determining protein MreC. | 0.688 |
| AEE51407.1 | AEE51405.1 | Halhy_3552 | Halhy_3550 | Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | InterPro IPR018004; KEGG: gur:Gura_3302 hypothetical protein; PFAM: KilA, N-terminal/APSES-type HTH DNA-binding domain; SPTR: Putative uncharacterized protein; IMG reference gene:2504772931; PFAM: KilA-N domain. | 0.465 |
| AEE51407.1 | AEE51406.1 | Halhy_3552 | Halhy_3551 | Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | KEGG: phe:Phep_3068 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504772932; PFAM: Protein of unknown function (DUF2851). | 0.505 |
| AEE51407.1 | AEE51408.1 | Halhy_3552 | Halhy_3553 | Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | Capsule synthesis protein, CapA; COGs: COG2843 Putative protein of poly-gamma-glutamate biosynthesis (capsule formation); InterPro IPR019079; KEGG: capsule synthesis protein, CapA; PFAM: Capsule synthesis protein, CapA; SPTR: Putative uncharacterized protein; IMG reference gene:2504772934; PFAM: Bacterial capsule synthesis protein PGA_cap. | 0.773 |
| AEE51407.1 | AEE51409.1 | Halhy_3552 | Halhy_3554 | Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | Penicillin-binding protein 2; COGs: COG0768 Cell division protein FtsI/penicillin-binding protein 2; InterPro IPR017790:IPR005311:IPR001460; KEGG: aas:Aasi_0246 hypothetical protein; PFAM: Penicillin-binding protein, transpeptidase; Penicillin-binding protein, dimerisation domain; PRIAM: Peptidoglycan glycosyltransferase; SPTR: Penicillin-binding protein 2; TIGRFAM: Penicillin-binding protein 2; IMG reference gene:2504772935; PFAM: Penicillin binding protein transpeptidase domain; Penicillin-binding Protein dimerisation domain; TIGRFAM: penicillin-binding protein 2. | 0.682 |
| AEE51407.1 | AEE51410.1 | Halhy_3552 | Halhy_3555 | Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | KEGG: phe:Phep_0806 rod shape-determining protein MreD; SPTR: Rod shape-determining protein MreD; IMG reference gene:2504772936. | 0.605 |
| AEE51407.1 | AEE51411.1 | Halhy_3552 | Halhy_3556 | Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | COGs: COG1792 Cell shape-determining protein; InterPro IPR007221; KEGG: zpr:ZPR_0660 rod shape-determining protein MreC; PFAM: Rod shape-determining protein MreC; SPTR: Rod shape-determining protein MreC; IMG reference gene:2504772937; PFAM: rod shape-determining protein MreC; TIGRFAM: rod shape-determining protein MreC. | 0.603 |
| AEE51407.1 | AEE51412.1 | Halhy_3552 | Halhy_3557 | Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | Cell shape determining protein, MreB/Mrl family; COGs: COG1077 Actin-like ATPase involved in cell morphogenesis; InterPro IPR004753; KEGG: mtt:Ftrac_2256 cell shape determining protein, MreB/mrl family; PFAM: Cell shape determining protein MreB/Mrl; SPTR: Cell shape determining protein, MreB/Mrl family; TIGRFAM: Cell shape determining protein MreB/Mrl; IMG reference gene:2504772938; PFAM: MreB/Mbl protein; TIGRFAM: cell shape determining protein, MreB/Mrl family. | 0.435 |
| AEE51408.1 | AEE48004.1 | Halhy_3553 | Halhy_0091 | Capsule synthesis protein, CapA; COGs: COG2843 Putative protein of poly-gamma-glutamate biosynthesis (capsule formation); InterPro IPR019079; KEGG: capsule synthesis protein, CapA; PFAM: Capsule synthesis protein, CapA; SPTR: Putative uncharacterized protein; IMG reference gene:2504772934; PFAM: Bacterial capsule synthesis protein PGA_cap. | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | 0.701 |
| AEE51408.1 | AEE51405.1 | Halhy_3553 | Halhy_3550 | Capsule synthesis protein, CapA; COGs: COG2843 Putative protein of poly-gamma-glutamate biosynthesis (capsule formation); InterPro IPR019079; KEGG: capsule synthesis protein, CapA; PFAM: Capsule synthesis protein, CapA; SPTR: Putative uncharacterized protein; IMG reference gene:2504772934; PFAM: Bacterial capsule synthesis protein PGA_cap. | InterPro IPR018004; KEGG: gur:Gura_3302 hypothetical protein; PFAM: KilA, N-terminal/APSES-type HTH DNA-binding domain; SPTR: Putative uncharacterized protein; IMG reference gene:2504772931; PFAM: KilA-N domain. | 0.465 |