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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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AEE51434.1COGs: COG0340 Biotin-(acetyl-CoA carboxylase) ligase; InterPro IPR004408:IPR004143; KEGG: sli:Slin_3003 biotin/acetyl-CoA-carboxylase ligase; PFAM: Biotin/lipoate A/B protein ligase; SPTR: Biotin-acetyl-CoA-carboxylase ligase; TIGRFAM: Biotin--acetyl-CoA-carboxylase ligase; IMG reference gene:2504772961; PFAM: Biotin/lipoate A/B protein ligase family; TIGRFAM: birA, biotin-[acetyl-CoA-carboxylase] ligase region. (259 aa)    
Predicted Functional Partners:
bioB
Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family.
  
 
 0.935
AEE48098.1
Pyruvate carboxylase; COGs: COG4770 Acetyl/propionyl-CoA carboxylase alpha subunit; InterPro IPR005481:IPR005479:IPR005482; KEGG: zpr:ZPR_1998 biotin carboxylase; PFAM: Carbamoyl phosphate synthetase, large subunit, ATP-binding; Carbamoyl phosphate synthase, large subunit, N-terminal; Biotin carboxylase, C-terminal; PRIAM: Pyruvate carboxylase; SPTR: Acetyl-CoA carboxylase, biotin carboxylase; IMG reference gene:2504769537; PFAM: Carbamoyl-phosphate synthase L chain, ATP binding domain; Biotin carboxylase C-terminal domain; Carbamoyl-phosphate synthase L chain, N-terminal domain; TIGRF [...]
 
  
 0.740
AEE48984.1
COGs: COG0331 (acyl-carrier-protein) S-malonyltransferase; InterPro IPR014043:IPR004410; KEGG: ppn:Palpr_0687 (AcyL-carrier-protein) S-malonyltransferase; PFAM: Acyl transferase; PRIAM: [Acyl-carrier-protein] S-malonyltransferase; SPTR: (Acyl-carrier-protein) S-malonyltransferase; TIGRFAM: Malonyl CoA-acyl carrier protein transacylase; IMG reference gene:2504770447; PFAM: Acyl transferase domain; TIGRFAM: malonyl CoA-acyl carrier protein transacylase.
 
   
 0.728
AEE50388.1
acetyl-CoA carboxylase, biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.
 
  
 0.722
AEE49459.1
Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.
 
 
 0.719
AEE50433.1
3-oxoacyl-(acyl-carrier-protein) synthase 2; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.
 
   
 0.690
AEE49876.1
Universal protein YeaZ; COGs: COG1214 Inactive homolog of metal-dependent protease putative molecular chaperone; InterPro IPR000905; KEGG: phe:Phep_1546 peptidase M22 glycoprotease; PFAM: Peptidase M22, glycoprotease; SPTR: Universal bacterial protein YeaZ; TIGRFAM: universal protein YeaZ; IMG reference gene:2504771357; PFAM: Glycoprotease family; TIGRFAM: universal bacterial protein YeaZ.
  
    0.662
AEE48111.1
COGs: COG4799 Acetyl-CoA carboxylase carboxyltransferase component (subunits alpha and beta); InterPro IPR000022; KEGG: lby:Lbys_1917 carboxyl transferase; PFAM: Carboxyl transferase; PRIAM: Propionyl-CoA carboxylase; SPTR: Carboxyl transferase; IMG reference gene:2504769550; PFAM: Carboxyl transferase domain.
 
 
 0.657
AEE51433.1
Competence/damage-inducible protein CinA; COGs: COG1058 nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA; InterPro IPR008135:IPR008136:IPR001453; KEGG: sli:Slin_1357 competence/damage-inducible protein CinA; PFAM: CinA, C-terminal; Molybdopterin binding; SPTR: CinA-like protein; TIGRFAM: Competence-induced protein CinA; CinA, C-terminal; IMG reference gene:2504772960; PFAM: Probable molybdopterin binding domain; Competence-damaged protein; TIGRFAM: competence/damage-inducible protein CinA N-terminal domain; competence/damage-inducible protein CinA C-termina [...]
  
  
 0.656
rsfS
Iojap-like protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
       0.617
Your Current Organism:
Haliscomenobacter hydrossis
NCBI taxonomy Id: 760192
Other names: H. hydrossis DSM 1100, Haliscomenobacter hydrossis DSM 1100
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