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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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nadENAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. (545 aa)    
Predicted Functional Partners:
nadK
Inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
 
  
 0.954
AEE48152.1
Cytidyltransferase-related domain protein; COGs: COG3172 ATPase/kinase involved in NAD metabolism; KEGG: gym:GYMC10_6274 cytidyltransferase-related domain protein; SPTR: Cytidyltransferase-related domain protein; IMG reference gene:2504769591; TIGRFAM: nicotinamide-nucleotide adenylyltransferase, NadR type; cytidyltransferase-related domain.
    
 0.951
nadD
Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
  
 
 0.950
cobB
COGs: COG0846 NAD-dependent protein deacetylase SIR2 family; HAMAP: NAD-dependent deacetylase; InterPro IPR003000; KEGG: zpr:ZPR_2106 NAD-dependent histone deacetylase; PFAM: NAD-dependent histone deacetylase, silent information regulator Sir2; SPTR: Putative uncharacterized protein; IMG reference gene:2504775815; PFAM: Sir2 family; Belongs to the sirtuin family. Class III subfamily.
    
 0.944
AEE54137.1
NAD(P)(+) transhydrogenase (AB-specific); The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family.
     
 0.927
AEE54135.1
NAD(P)(+) transhydrogenase (AB-specific); COGs: COG3288 NAD/NADP transhydrogenase alpha subunit; InterPro IPR007886:IPR007698; KEGG: rru:Rru_A2183 NAD(P)(+) transhydrogenase (AB-specific); PFAM: Alanine dehydrogenase/PNT, C-terminal; Alanine dehydrogenase/PNT, N-terminal; PRIAM: NAD(P)(+) transhydrogenase (AB-specific); SPTR: NAD(P) transhydrogenase, alpha subunit part 1; IMG reference gene:2504775724; PFAM: Alanine dehydrogenase/PNT, C-terminal domain; Alanine dehydrogenase/PNT, N-terminal domain; TIGRFAM: NAD(P) transhydrogenase, alpha subunit.
     
 0.907
AEE54136.1
COGs: COG3288 NAD/NADP transhydrogenase alpha subunit; KEGG: cpi:Cpin_6490 pyridine nucleotide transhydrogenase subunit alpha; SPTR: Pyridine nucleotide transhydrogenase subunit alpha; IMG reference gene:2504775725.
     
 0.907
AEE51449.1
ADP-ribosylation/Crystallin J1; COGs: COG1397 ADP-ribosylglycohydrolase; InterPro IPR005502; KEGG: npu:Npun_F4650 ADP-ribosylation/crystallin J1; PFAM: ADP-ribosylation/Crystallin J1; SPTR: ADP-ribosylhydrolase like 2; IMG reference gene:2504772978; PFAM: ADP-ribosylglycohydrolase.
       0.781
AEE49915.1
KEGG: sli:Slin_5879 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504771397.
  
 
 0.662
cutC
CutC family protein; Participates in the control of copper homeostasis. Belongs to the CutC family.
   
   0.644
Your Current Organism:
Haliscomenobacter hydrossis
NCBI taxonomy Id: 760192
Other names: H. hydrossis DSM 1100, Haliscomenobacter hydrossis DSM 1100
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