Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AEE51917.1Two component transcriptional regulator, LuxR family; COGs: COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; InterPro IPR001789:IPR000792; KEGG: syn:slr1213 AraC family transcription regulator; PFAM: Signal transduction response regulator, receiver region; Transcription regulator LuxR, C-terminal; SMART: Signal transduction response regulator, receiver region; Transcription regulator LuxR, C-terminal; SPTR: AraC subfamily; IMG reference gene:2504773455; PFAM: Response regulator receiver domain; Bacterial regulatory proteins, luxR family. (207 aa)    
Predicted Functional Partners:
AEE51916.1
COGs: COG3920 Signal transduction histidine kinase; InterPro IPR011495:IPR003594; KEGG: sli:Slin_2255 signal transduction histidine kinase; PFAM: Signal transduction histidine kinase, subgroup 2, dimerisation and phosphoacceptor region; ATP-binding region, ATPase-like; SMART: ATP-binding region, ATPase-like; SPTR: Sensory box histidine kinase; IMG reference gene:2504773454; PFAM: Histidine kinase; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase.
 
     0.924
AEE53333.1
Two component transcriptional regulator, LuxR family; COGs: COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; InterPro IPR001789:IPR000792; KEGG: cac:CA_C0240 response regulator; PFAM: Signal transduction response regulator, receiver region; Transcription regulator LuxR, C-terminal; SMART: Signal transduction response regulator, receiver region; Transcription regulator LuxR, C-terminal; SPTR: Two component transcriptional regulator, LuxR family; IMG reference gene:2504774906; PFAM: Response regulator receiver domain; Bacterial regulatory p [...]
  
     0.708
AEE53673.1
Two component transcriptional regulator, LuxR family; COGs: COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; InterPro IPR001789:IPR000792; KEGG: cpi:Cpin_2387 two component transcriptional regulator, LuxR family; PFAM: Signal transduction response regulator, receiver region; Transcription regulator LuxR, C-terminal; SMART: Signal transduction response regulator, receiver region; Transcription regulator LuxR, C-terminal; SPTR: Two component transcriptional regulator, LuxR family; IMG reference gene:2504775248; PFAM: Response regulator rece [...]
  
     0.696
AEE54018.1
COGs: COG3920 Signal transduction histidine kinase; InterPro IPR001440:IPR011495:IPR003594:IPR019734; KEGG: cyc:PCC7424_4563 signal transduction histidine kinase; PFAM: Signal transduction histidine kinase, subgroup 2, dimerisation and phosphoacceptor region; Tetratricopeptide TPR-1; ATP-binding region, ATPase-like; SMART: ATP-binding region, ATPase-like; Tetratricopeptide repeat; SPTR: Sensory box histidine kinase; IMG reference gene:2504775604; PFAM: Histidine kinase; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Tetratricopeptide repeat.
 
     0.688
AEE49532.1
Hpt sensor hybrid histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003661:IPR003594:IPR001789:IPR008207; KEGG: cts:Ctha_0019 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; Signal transduction response regulator, receiver region; Signal transduction histidine kinase, phosphotransfer (Hpt) region; SMART: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; Signal transductio [...]
 
 
 0.678
AEE48892.1
Two component transcriptional regulator, LuxR family; COGs: COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; InterPro IPR001789:IPR000792; KEGG: cpi:Cpin_4160 two component transcriptional regulator, LuxR family; PFAM: Signal transduction response regulator, receiver region; Transcription regulator LuxR, C-terminal; SMART: Transcription regulator LuxR, C-terminal; Signal transduction response regulator, receiver region; SPTR: Two component transcriptional regulator, LuxR family; IMG reference gene:2504770353; PFAM: Response regulator rece [...]
  
     0.674
AEE52692.1
COGs: COG3920 Signal transduction histidine kinase; InterPro IPR019734:IPR001440:IPR011495:IPR003594; KEGG: sli:Slin_3428 signal transduction histidine kinase; PFAM: Signal transduction histidine kinase, subgroup 2, dimerisation and phosphoacceptor region; Tetratricopeptide TPR-1; ATP-binding region, ATPase-like; SPTR: Signal transduction histidine kinase; IMG reference gene:2504774257; PFAM: Histidine kinase; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase.
 
     0.660
AEE53486.1
PAS/PAC sensor hybrid histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterProIPR000014:IPR003661:IPR003594:IPR001789:IPR 013656:IPR013767; KEGG: ppn:Palpr_2639 pas/pac sensor hybrid histidine kinase; PFAM: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; PAS fold-4; PAS fold; Signal transduction response regulator, receiver region; SMART: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; PAS; Signal transduction response reg [...]
   
 
 0.657
AEE52090.1
Two component transcriptional regulator, LuxR family; COGs: COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; InterPro IPR001789:IPR000792; KEGG: mtt:Ftrac_1178 two component transcriptional regulator, LuxR family; PFAM: Signal transduction response regulator, receiver region; Transcription regulator LuxR, C-terminal; SMART: Signal transduction response regulator, receiver region; Transcription regulator LuxR, C-terminal; SPTR: Two component transcriptional regulator, LuxR family; IMG reference gene:2504773631; PFAM: Response regulator rec [...]
  
     0.653
AEE49389.1
Two component transcriptional regulator, LuxR family; COGs: COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; InterPro IPR001789:IPR000792; KEGG: fjo:Fjoh_0036 two component LuxR family transcriptional regulator; PFAM: Signal transduction response regulator, receiver region; Transcription regulator LuxR, C-terminal; SMART: Signal transduction response regulator, receiver region; Transcription regulator LuxR, C-terminal; SPTR: DNA-binding response regulator, LuxR family protein; IMG reference gene:2504770857; PFAM: Response regulator receiv [...]
  
     0.646
Your Current Organism:
Haliscomenobacter hydrossis
NCBI taxonomy Id: 760192
Other names: H. hydrossis DSM 1100, Haliscomenobacter hydrossis DSM 1100
Server load: low (10%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.