Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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AEE51929.1Endonuclease/exonuclease/phosphatase; InterPro IPR005135; KEGG: mba:Mbar_A1825 hypothetical protein; PFAM: Endonuclease/exonuclease/phosphatase; SPTR: Putative uncharacterized protein; IMG reference gene:2504773467; PFAM: Endonuclease/Exonuclease/phosphatase family. (237 aa)    
Predicted Functional Partners:
AEE51234.1
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
   
 0.752
AEE51930.1
TspO and MBR like protein; COGs: COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog); InterPro IPR004307; KEGG: mma:MM_0963 integral membrane protein; PFAM: TspO/MBR-related protein; SPTR: Integral membrane protein; IMG reference gene:2504773468; PFAM: TspO/MBR family.
       0.743
AEE51931.1
Putative transcriptional regulator, Crp/Fnr family; COGs: COG0664 cAMP-binding protein - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase; InterPro IPR000595; KEGG: mtt:Ftrac_1323 transcriptional regulator, crp/fnr family; PFAM: Cyclic nucleotide-binding; SMART: Cyclic nucleotide-binding; SPTR: Putative transcriptional regulator, Crp/Fnr family; IMG reference gene:2504773469; PFAM: Cyclic nucleotide-binding domain.
       0.737
AEE51928.1
KEGG: cyt:cce_5073 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504773466.
       0.714
AEE51927.1
InterPro IPR008538; KEGG: sli:Slin_0255 protein of unknown function DUF820; PFAM: Protein of unknown function DUF820; SPTR: Putative uncharacterized protein; IMG reference gene:2504773465; PFAM: Protein of unknown function (DUF820).
       0.704
AEE51384.1
A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs.
    
 0.684
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
 0.683
AEE51357.1
Pseudouridine synthase Rsu; COGs: COG1187 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthase; InterPro IPR002942:IPR000748:IPR006145; KEGG: rbi:RB2501_08660 ribosomal large subunit pseudouridine synthase B; PFAM: Pseudouridine synthase, RsuA and RluB/C/D/E/F; RNA-binding S4; SMART: RNA-binding S4; SPTR: Ribosomal large subunit pseudouridine synthase B; TIGRFAM: Pseudouridine synthase, RsuA and RluB/E/F; IMG reference gene:2504772883; PFAM: RNA pseudouridylate synthase; S4 domain; TIGRFAM: pseudouridine synthase; Belongs to the pseudouridine synthase RsuA [...]
  
    0.635
AEE52673.1
Pseudouridine synthase Rsu; COGs: COG1187 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthase; InterPro IPR000748:IPR002942:IPR006145; KEGG: cpr:CPR_2299 ribosomal large subunit pseudouridine synthase F; PFAM: Pseudouridine synthase, RsuA and RluB/C/D/E/F; RNA-binding S4; SMART: RNA-binding S4; SPTR: RNA pseudouridine synthase family protein; TIGRFAM: Pseudouridine synthase, RsuA and RluB/E/F; IMG reference gene:2504774235; PFAM: RNA pseudouridylate synthase; S4 domain; TIGRFAM: pseudouridine synthase; Belongs to the pseudouridine synthase RsuA family.
  
    0.635
AEE53905.1
Pseudouridine synthase Rsu; COGs: COG1187 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthase; InterPro IPR000748:IPR006145; KEGG: naz:Aazo_4021 pseudouridine synthase; PFAM: Pseudouridine synthase, RsuA and RluB/C/D/E/F; SPTR: Pseudouridine synthase, Rsu; TIGRFAM: Pseudouridine synthase, RsuA and RluB/E/F; IMG reference gene:2504775485; PFAM: RNA pseudouridylate synthase; TIGRFAM: pseudouridine synthase; Belongs to the pseudouridine synthase RsuA family.
  
    0.635
Your Current Organism:
Haliscomenobacter hydrossis
NCBI taxonomy Id: 760192
Other names: H. hydrossis DSM 1100, Haliscomenobacter hydrossis DSM 1100
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