Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AEE51999.1Isopenicillin-N epimerase; COGs: COG0520 Selenocysteine lyase; InterPro IPR000192; KEGG: sli:Slin_6132 aminotransferase class V; PFAM: Aminotransferase, class V/Cysteine desulfurase; PRIAM: Isopenicillin-N epimerase; SPTR: Aminotransferase class V; IMG reference gene:2504773539; PFAM: Aminotransferase class-V. (423 aa)    
Predicted Functional Partners:
AEE54184.1
SUF system FeS assembly protein, NifU family; COGs: COG0822 NifU homolog involved in Fe-S cluster formation; InterPro IPR011341:IPR002871; KEGG: tmz:Tmz1t_1895 SUF system FeS assembly protein, NifU family; PFAM: NIF system FeS cluster assembly, NifU, N-terminal; SPTR: SUF system FeS assembly protein, NifU family; TIGRFAM: SUF system FeS cluster assembly, SufU scaffold; IMG reference gene:2504775773; PFAM: NifU-like N terminal domain; TIGRFAM: SUF system FeS assembly protein, NifU family.
 
 
 0.861
AEE49237.1
FeS cluster assembly scaffold IscU; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.
  
 
 0.804
AEE51998.1
Na+/H+ antiporter; Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
       0.690
AEE52000.1
Protein of unknown function DUF1684; COGs: COG3358 conserved hypothetical protein; InterPro IPR012467; KEGG: sli:Slin_4806 protein of unknown function DUF1684; PFAM: Protein of unknown function DUF1684; SPTR: Putative uncharacterized protein; IMG reference gene:2504773540; PFAM: Protein of unknown function (DUF1684).
       0.555
AEE53581.1
Amidohydrolase; COGs: COG1228 Imidazolonepropionase and related amidohydrolase; InterPro IPR006680; KEGG: sli:Slin_5309 amidohydrolase; PFAM: Amidohydrolase 1; SPTR: Amidohydrolase family enzyme; IMG reference gene:2504775156; PFAM: Amidohydrolase family.
  
     0.500
AEE52358.1
COGs: COG2366 Protein related to penicillin acylase; InterPro IPR002692; KEGG: sli:Slin_4469 peptidase S45 penicillin amidase; PFAM: Peptidase S45, penicillin amidase; PRIAM: Glutaryl-7-aminocephalosporanic-acid acylase; SPTR: Peptidase S45 penicillin amidase; IMG reference gene:2504773905; PFAM: Penicillin amidase.
  
    0.479
AEE53354.1
Amidohydrolase; COGs: COG1473 Metal-dependent amidase/aminoacylase/carboxypeptidase; InterPro IPR010168; KEGG: fbc:FB2170_13923 hypothetical protein; SPTR: Amidohydrolase; TIGRFAM: Peptidase M20D, amidohydrolase; IMG reference gene:2504774927; PFAM: Peptidase dimerisation domain; TIGRFAM: amidohydrolase.
  
    0.473
AEE54329.1
COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterProIPR011895:IPR002880:IPR019752:IPR019456:IPR 001450:IPR011766; KEGG: mca:MCA0769 pyruvate ferredoxin/flavodoxin oxidoreductase family protein; PFAM: Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal; Pyruvate/ketoisovalerate oxidoreductase; Pyruvate-flavodoxin oxidoreductase, EKR domain; 4Fe-4S ferredoxin, iron-sulphur binding, subgroup; Thiamine pyrophosphate enzyme, C-terminal TPP-binding; PRIAM: Pyruvate dehydrogenase (NADP(+)); SPTR: Pyruvate ferredoxin/fla [...]
  
  
 0.454
AEE53832.1
Aminotransferase class V; COGs: COG0520 Selenocysteine lyase; InterPro IPR000192; KEGG: cat:CA2559_02090 hypothetical protein; PFAM: Aminotransferase, class V/Cysteine desulfurase; SPTR: Aminotransferase, class V superfamily; IMG reference gene:2504775411; PFAM: Aminotransferase class-V.
  
     0.426
AEE49862.1
KEGG: fbc:FB2170_02290 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504771338; PFAM: Putative esterase.
  
    0.419
Your Current Organism:
Haliscomenobacter hydrossis
NCBI taxonomy Id: 760192
Other names: H. hydrossis DSM 1100, Haliscomenobacter hydrossis DSM 1100
Server load: low (12%) [HD]