| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AEE49237.1 | AEE51999.1 | Halhy_1342 | Halhy_4153 | FeS cluster assembly scaffold IscU; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. | Isopenicillin-N epimerase; COGs: COG0520 Selenocysteine lyase; InterPro IPR000192; KEGG: sli:Slin_6132 aminotransferase class V; PFAM: Aminotransferase, class V/Cysteine desulfurase; PRIAM: Isopenicillin-N epimerase; SPTR: Aminotransferase class V; IMG reference gene:2504773539; PFAM: Aminotransferase class-V. | 0.804 |
| AEE49237.1 | AEE53832.1 | Halhy_1342 | Halhy_6009 | FeS cluster assembly scaffold IscU; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. | Aminotransferase class V; COGs: COG0520 Selenocysteine lyase; InterPro IPR000192; KEGG: cat:CA2559_02090 hypothetical protein; PFAM: Aminotransferase, class V/Cysteine desulfurase; SPTR: Aminotransferase, class V superfamily; IMG reference gene:2504775411; PFAM: Aminotransferase class-V. | 0.804 |
| AEE49237.1 | AEE54329.1 | Halhy_1342 | Halhy_6513 | FeS cluster assembly scaffold IscU; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. | COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterProIPR011895:IPR002880:IPR019752:IPR019456:IPR 001450:IPR011766; KEGG: mca:MCA0769 pyruvate ferredoxin/flavodoxin oxidoreductase family protein; PFAM: Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal; Pyruvate/ketoisovalerate oxidoreductase; Pyruvate-flavodoxin oxidoreductase, EKR domain; 4Fe-4S ferredoxin, iron-sulphur binding, subgroup; Thiamine pyrophosphate enzyme, C-terminal TPP-binding; PRIAM: Pyruvate dehydrogenase (NADP(+)); SPTR: Pyruvate ferredoxin/fla [...] | 0.544 |
| AEE49862.1 | AEE51999.1 | Halhy_1977 | Halhy_4153 | KEGG: fbc:FB2170_02290 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504771338; PFAM: Putative esterase. | Isopenicillin-N epimerase; COGs: COG0520 Selenocysteine lyase; InterPro IPR000192; KEGG: sli:Slin_6132 aminotransferase class V; PFAM: Aminotransferase, class V/Cysteine desulfurase; PRIAM: Isopenicillin-N epimerase; SPTR: Aminotransferase class V; IMG reference gene:2504773539; PFAM: Aminotransferase class-V. | 0.419 |
| AEE49862.1 | AEE53581.1 | Halhy_1977 | Halhy_5758 | KEGG: fbc:FB2170_02290 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504771338; PFAM: Putative esterase. | Amidohydrolase; COGs: COG1228 Imidazolonepropionase and related amidohydrolase; InterPro IPR006680; KEGG: sli:Slin_5309 amidohydrolase; PFAM: Amidohydrolase 1; SPTR: Amidohydrolase family enzyme; IMG reference gene:2504775156; PFAM: Amidohydrolase family. | 0.510 |
| AEE51998.1 | AEE51999.1 | Halhy_4152 | Halhy_4153 | Na+/H+ antiporter; Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. | Isopenicillin-N epimerase; COGs: COG0520 Selenocysteine lyase; InterPro IPR000192; KEGG: sli:Slin_6132 aminotransferase class V; PFAM: Aminotransferase, class V/Cysteine desulfurase; PRIAM: Isopenicillin-N epimerase; SPTR: Aminotransferase class V; IMG reference gene:2504773539; PFAM: Aminotransferase class-V. | 0.690 |
| AEE51998.1 | AEE52000.1 | Halhy_4152 | Halhy_4154 | Na+/H+ antiporter; Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. | Protein of unknown function DUF1684; COGs: COG3358 conserved hypothetical protein; InterPro IPR012467; KEGG: sli:Slin_4806 protein of unknown function DUF1684; PFAM: Protein of unknown function DUF1684; SPTR: Putative uncharacterized protein; IMG reference gene:2504773540; PFAM: Protein of unknown function (DUF1684). | 0.559 |
| AEE51999.1 | AEE49237.1 | Halhy_4153 | Halhy_1342 | Isopenicillin-N epimerase; COGs: COG0520 Selenocysteine lyase; InterPro IPR000192; KEGG: sli:Slin_6132 aminotransferase class V; PFAM: Aminotransferase, class V/Cysteine desulfurase; PRIAM: Isopenicillin-N epimerase; SPTR: Aminotransferase class V; IMG reference gene:2504773539; PFAM: Aminotransferase class-V. | FeS cluster assembly scaffold IscU; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. | 0.804 |
| AEE51999.1 | AEE49862.1 | Halhy_4153 | Halhy_1977 | Isopenicillin-N epimerase; COGs: COG0520 Selenocysteine lyase; InterPro IPR000192; KEGG: sli:Slin_6132 aminotransferase class V; PFAM: Aminotransferase, class V/Cysteine desulfurase; PRIAM: Isopenicillin-N epimerase; SPTR: Aminotransferase class V; IMG reference gene:2504773539; PFAM: Aminotransferase class-V. | KEGG: fbc:FB2170_02290 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504771338; PFAM: Putative esterase. | 0.419 |
| AEE51999.1 | AEE51998.1 | Halhy_4153 | Halhy_4152 | Isopenicillin-N epimerase; COGs: COG0520 Selenocysteine lyase; InterPro IPR000192; KEGG: sli:Slin_6132 aminotransferase class V; PFAM: Aminotransferase, class V/Cysteine desulfurase; PRIAM: Isopenicillin-N epimerase; SPTR: Aminotransferase class V; IMG reference gene:2504773539; PFAM: Aminotransferase class-V. | Na+/H+ antiporter; Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. | 0.690 |
| AEE51999.1 | AEE52000.1 | Halhy_4153 | Halhy_4154 | Isopenicillin-N epimerase; COGs: COG0520 Selenocysteine lyase; InterPro IPR000192; KEGG: sli:Slin_6132 aminotransferase class V; PFAM: Aminotransferase, class V/Cysteine desulfurase; PRIAM: Isopenicillin-N epimerase; SPTR: Aminotransferase class V; IMG reference gene:2504773539; PFAM: Aminotransferase class-V. | Protein of unknown function DUF1684; COGs: COG3358 conserved hypothetical protein; InterPro IPR012467; KEGG: sli:Slin_4806 protein of unknown function DUF1684; PFAM: Protein of unknown function DUF1684; SPTR: Putative uncharacterized protein; IMG reference gene:2504773540; PFAM: Protein of unknown function (DUF1684). | 0.555 |
| AEE51999.1 | AEE52358.1 | Halhy_4153 | Halhy_4518 | Isopenicillin-N epimerase; COGs: COG0520 Selenocysteine lyase; InterPro IPR000192; KEGG: sli:Slin_6132 aminotransferase class V; PFAM: Aminotransferase, class V/Cysteine desulfurase; PRIAM: Isopenicillin-N epimerase; SPTR: Aminotransferase class V; IMG reference gene:2504773539; PFAM: Aminotransferase class-V. | COGs: COG2366 Protein related to penicillin acylase; InterPro IPR002692; KEGG: sli:Slin_4469 peptidase S45 penicillin amidase; PFAM: Peptidase S45, penicillin amidase; PRIAM: Glutaryl-7-aminocephalosporanic-acid acylase; SPTR: Peptidase S45 penicillin amidase; IMG reference gene:2504773905; PFAM: Penicillin amidase. | 0.479 |
| AEE51999.1 | AEE53354.1 | Halhy_4153 | Halhy_5529 | Isopenicillin-N epimerase; COGs: COG0520 Selenocysteine lyase; InterPro IPR000192; KEGG: sli:Slin_6132 aminotransferase class V; PFAM: Aminotransferase, class V/Cysteine desulfurase; PRIAM: Isopenicillin-N epimerase; SPTR: Aminotransferase class V; IMG reference gene:2504773539; PFAM: Aminotransferase class-V. | Amidohydrolase; COGs: COG1473 Metal-dependent amidase/aminoacylase/carboxypeptidase; InterPro IPR010168; KEGG: fbc:FB2170_13923 hypothetical protein; SPTR: Amidohydrolase; TIGRFAM: Peptidase M20D, amidohydrolase; IMG reference gene:2504774927; PFAM: Peptidase dimerisation domain; TIGRFAM: amidohydrolase. | 0.473 |
| AEE51999.1 | AEE53581.1 | Halhy_4153 | Halhy_5758 | Isopenicillin-N epimerase; COGs: COG0520 Selenocysteine lyase; InterPro IPR000192; KEGG: sli:Slin_6132 aminotransferase class V; PFAM: Aminotransferase, class V/Cysteine desulfurase; PRIAM: Isopenicillin-N epimerase; SPTR: Aminotransferase class V; IMG reference gene:2504773539; PFAM: Aminotransferase class-V. | Amidohydrolase; COGs: COG1228 Imidazolonepropionase and related amidohydrolase; InterPro IPR006680; KEGG: sli:Slin_5309 amidohydrolase; PFAM: Amidohydrolase 1; SPTR: Amidohydrolase family enzyme; IMG reference gene:2504775156; PFAM: Amidohydrolase family. | 0.500 |
| AEE51999.1 | AEE53832.1 | Halhy_4153 | Halhy_6009 | Isopenicillin-N epimerase; COGs: COG0520 Selenocysteine lyase; InterPro IPR000192; KEGG: sli:Slin_6132 aminotransferase class V; PFAM: Aminotransferase, class V/Cysteine desulfurase; PRIAM: Isopenicillin-N epimerase; SPTR: Aminotransferase class V; IMG reference gene:2504773539; PFAM: Aminotransferase class-V. | Aminotransferase class V; COGs: COG0520 Selenocysteine lyase; InterPro IPR000192; KEGG: cat:CA2559_02090 hypothetical protein; PFAM: Aminotransferase, class V/Cysteine desulfurase; SPTR: Aminotransferase, class V superfamily; IMG reference gene:2504775411; PFAM: Aminotransferase class-V. | 0.426 |
| AEE51999.1 | AEE54184.1 | Halhy_4153 | Halhy_6365 | Isopenicillin-N epimerase; COGs: COG0520 Selenocysteine lyase; InterPro IPR000192; KEGG: sli:Slin_6132 aminotransferase class V; PFAM: Aminotransferase, class V/Cysteine desulfurase; PRIAM: Isopenicillin-N epimerase; SPTR: Aminotransferase class V; IMG reference gene:2504773539; PFAM: Aminotransferase class-V. | SUF system FeS assembly protein, NifU family; COGs: COG0822 NifU homolog involved in Fe-S cluster formation; InterPro IPR011341:IPR002871; KEGG: tmz:Tmz1t_1895 SUF system FeS assembly protein, NifU family; PFAM: NIF system FeS cluster assembly, NifU, N-terminal; SPTR: SUF system FeS assembly protein, NifU family; TIGRFAM: SUF system FeS cluster assembly, SufU scaffold; IMG reference gene:2504775773; PFAM: NifU-like N terminal domain; TIGRFAM: SUF system FeS assembly protein, NifU family. | 0.861 |
| AEE51999.1 | AEE54329.1 | Halhy_4153 | Halhy_6513 | Isopenicillin-N epimerase; COGs: COG0520 Selenocysteine lyase; InterPro IPR000192; KEGG: sli:Slin_6132 aminotransferase class V; PFAM: Aminotransferase, class V/Cysteine desulfurase; PRIAM: Isopenicillin-N epimerase; SPTR: Aminotransferase class V; IMG reference gene:2504773539; PFAM: Aminotransferase class-V. | COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterProIPR011895:IPR002880:IPR019752:IPR019456:IPR 001450:IPR011766; KEGG: mca:MCA0769 pyruvate ferredoxin/flavodoxin oxidoreductase family protein; PFAM: Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal; Pyruvate/ketoisovalerate oxidoreductase; Pyruvate-flavodoxin oxidoreductase, EKR domain; 4Fe-4S ferredoxin, iron-sulphur binding, subgroup; Thiamine pyrophosphate enzyme, C-terminal TPP-binding; PRIAM: Pyruvate dehydrogenase (NADP(+)); SPTR: Pyruvate ferredoxin/fla [...] | 0.454 |
| AEE52000.1 | AEE51998.1 | Halhy_4154 | Halhy_4152 | Protein of unknown function DUF1684; COGs: COG3358 conserved hypothetical protein; InterPro IPR012467; KEGG: sli:Slin_4806 protein of unknown function DUF1684; PFAM: Protein of unknown function DUF1684; SPTR: Putative uncharacterized protein; IMG reference gene:2504773540; PFAM: Protein of unknown function (DUF1684). | Na+/H+ antiporter; Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. | 0.559 |
| AEE52000.1 | AEE51999.1 | Halhy_4154 | Halhy_4153 | Protein of unknown function DUF1684; COGs: COG3358 conserved hypothetical protein; InterPro IPR012467; KEGG: sli:Slin_4806 protein of unknown function DUF1684; PFAM: Protein of unknown function DUF1684; SPTR: Putative uncharacterized protein; IMG reference gene:2504773540; PFAM: Protein of unknown function (DUF1684). | Isopenicillin-N epimerase; COGs: COG0520 Selenocysteine lyase; InterPro IPR000192; KEGG: sli:Slin_6132 aminotransferase class V; PFAM: Aminotransferase, class V/Cysteine desulfurase; PRIAM: Isopenicillin-N epimerase; SPTR: Aminotransferase class V; IMG reference gene:2504773539; PFAM: Aminotransferase class-V. | 0.555 |
| AEE52358.1 | AEE51999.1 | Halhy_4518 | Halhy_4153 | COGs: COG2366 Protein related to penicillin acylase; InterPro IPR002692; KEGG: sli:Slin_4469 peptidase S45 penicillin amidase; PFAM: Peptidase S45, penicillin amidase; PRIAM: Glutaryl-7-aminocephalosporanic-acid acylase; SPTR: Peptidase S45 penicillin amidase; IMG reference gene:2504773905; PFAM: Penicillin amidase. | Isopenicillin-N epimerase; COGs: COG0520 Selenocysteine lyase; InterPro IPR000192; KEGG: sli:Slin_6132 aminotransferase class V; PFAM: Aminotransferase, class V/Cysteine desulfurase; PRIAM: Isopenicillin-N epimerase; SPTR: Aminotransferase class V; IMG reference gene:2504773539; PFAM: Aminotransferase class-V. | 0.479 |