Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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AEE52105.1MazG family protein; COGs: COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like (predicted pyrophosphatase) domain; InterPro IPR004518:IPR011551; KEGG: MazG family protein; PFAM: NTP pyrophosphohydrolase MazG, putative catalytic core; SPTR: MazG family protein; TIGRFAM: NTP pyrophosphohydrolase MazG, bacterial; IMG reference gene:2504773647; PFAM: MazG nucleotide pyrophosphohydrolase domain; TIGRFAM: MazG family protein. (252 aa)    
Predicted Functional Partners:
thyA
Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
   
 
 0.632
AEE53593.1
COGs: COG1816 Adenosine deaminase; HAMAP: Adenosine deaminase; InterPro IPR006330:IPR001365; KEGG: plu:plu2772 hypothetical protein; PFAM: Adenosine/AMP deaminase; PRIAM: Adenosine deaminase; SPTR: Adenosine deaminase 1; TIGRFAM: Adenosine deaminase; IMG reference gene:2504775168; PFAM: Adenosine/AMP deaminase; TIGRFAM: adenosine deaminase.
      0.567
AEE52106.1
KEGG: mtt:Ftrac_2797 membrane or secreted protein; SPTR: Membrane or secreted protein; IMG reference gene:2504773648.
       0.548
gpmI
2,3-bisphosphoglycerate-independent phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate.
      0.525
AEE52104.1
LmbE family protein; COGs: COG2120 conserved hypothetical protein LmbE homologs; InterPro IPR003737; KEGG: LmbE family protein; PFAM: N-acetylglucosaminyl phosphatidylinositol deacetylase; SPTR: YpjG; IMG reference gene:2504773646; PFAM: GlcNAc-PI de-N-acetylase; TIGRFAM: bacillithiol biosynthesis deacetylase BshB1.
       0.510
AEE48194.1
RNA-binding S4 domain protein; COGs: COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog); InterPro IPR002942; KEGG: aai:AARI_26630 S4 domain-containing protein; PFAM: RNA-binding S4; SMART: RNA-binding S4; SPTR: Heat shock protein Hsp15; IMG reference gene:2504769637; PFAM: S4 domain.
  
    0.501
ndk
Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
     
  0.500
AEE52684.1
Queuosine biosynthesis protein QueD; COGs: COG0720 6-pyruvoyl-tetrahydropterin synthase; InterPro IPR007115; KEGG: vex:VEA_003152 queuosine biosynthesis QueD PTPS-I; PFAM: 6-pyruvoyl tetrahydropterin synthase-related; SPTR: 6-pyruvoyl-tetrahydropterin synthase; TIGRFAM: queuosine biosynthesis protein QueD; IMG reference gene:2504774247; PFAM: 6-pyruvoyl tetrahydropterin synthase; TIGRFAM: queuosine biosynthesis protein QueD; 6-pyruvoyl tetrahydropterin synthase/QueD family protein.
 
  
 0.482
era
GTP-binding protein Era-like-protein; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
   
 
 0.404
Your Current Organism:
Haliscomenobacter hydrossis
NCBI taxonomy Id: 760192
Other names: H. hydrossis DSM 1100, Haliscomenobacter hydrossis DSM 1100
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