Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AEE52136.1Histidine kinase; COGs: COG2972 signal transduction protein with a C-terminal ATPase domain; InterPro IPR010559:IPR003594; KEGG: rbi:RB2501_03455 ATP-binding region, ATPase-like protein; PFAM: Signal transduction histidine kinase, internal region; ATP-binding region, ATPase-like; SPTR: ATP-binding region, ATPase-like protein; IMG reference gene:2504773678; PFAM: Histidine kinase. (547 aa)    
Predicted Functional Partners:
AEE52135.1
Two component transcriptional regulator, LytTR family; COGs: COG3279 Response regulator of the LytR/AlgR family; InterPro IPR001789:IPR007492; KEGG: sli:Slin_6582 two component transcriptional regulator, LytTR family; PFAM: Signal transduction response regulator, receiver region; LytTr DNA-binding region; SMART: Signal transduction response regulator, receiver region; SPTR: Two component transcriptional regulator, LytTR family; IMG reference gene:2504773677; PFAM: Response regulator receiver domain; LytTr DNA-binding domain.
 
  
 0.923
AEE52372.1
Two component transcriptional regulator, LytTR family; COGs: COG3279 Response regulator of the LytR/AlgR family; InterPro IPR001789:IPR007492; KEGG: chu:CHU_0254 response regulator; PFAM: LytTr DNA-binding region; Signal transduction response regulator, receiver region; SMART: Signal transduction response regulator, receiver region; SPTR: Response regulator; IMG reference gene:2504773919; PFAM: Response regulator receiver domain; LytTr DNA-binding domain.
 
  
 0.814
AEE49227.1
Two component transcriptional regulator, LytTR family; COGs: COG3279 Response regulator of the LytR/AlgR family; InterPro IPR001789:IPR007492; KEGG: cpi:Cpin_0671 two component transcriptional regulator, LytTR family; PFAM: LytTr DNA-binding region; Signal transduction response regulator, receiver region; SMART: Signal transduction response regulator, receiver region; SPTR: Putative uncharacterized protein; IMG reference gene:2504770693; PFAM: Response regulator receiver domain; LytTr DNA-binding domain.
 
  
 0.812
AEE49198.1
Periplasmic binding protein/LacI transcriptional regulator; COGs: COG1879 ABC-type sugar transport system periplasmic component; KEGG: csc:Csac_0242 periplasmic binding protein/LacI transcriptional regulator; SPTR: Putative uncharacterized protein; IMG reference gene:2504770664; PFAM: family.
  
 
 0.810
AEE49040.1
Two component transcriptional regulator, LytTR family; COGs: COG3279 Response regulator of the LytR/AlgR family; InterPro IPR001789:IPR007492; KEGG: cpi:Cpin_1844 two component transcriptional regulator, LytTR family; PFAM: Signal transduction response regulator, receiver region; LytTr DNA-binding region; SMART: Signal transduction response regulator, receiver region; SPTR: Two component transcriptional regulator, LytTR family; IMG reference gene:2504770503; PFAM: Response regulator receiver domain; LytTr DNA-binding domain.
 
  
 0.809
AEE51613.1
Two component transcriptional regulator, LytTR family; COGs: COG3279 Response regulator of the LytR/AlgR family; InterPro IPR001789:IPR007492; KEGG: mtt:Ftrac_1103 two component transcriptional regulator, LytTR family; PFAM: LytTr DNA-binding region; Signal transduction response regulator, receiver region; SMART: Signal transduction response regulator, receiver region; SPTR: Two component transcriptional regulator, LytTR family; IMG reference gene:2504773142; PFAM: Response regulator receiver domain; LytTr DNA-binding domain.
 
  
 0.808
AEE53985.1
Two component transcriptional regulator, LytTR family; COGs: COG3279 Response regulator of the LytR/AlgR family; InterPro IPR001789:IPR007492; KEGG: fjo:Fjoh_1345 LytTR family two component transcriptional regulator; PFAM: Signal transduction response regulator, receiver region; LytTr DNA-binding region; SMART: Signal transduction response regulator, receiver region; SPTR: Two component transcriptional regulator, LytTR family; IMG reference gene:2504775565; PFAM: Response regulator receiver domain; LytTr DNA-binding domain.
 
  
 0.808
AEE48544.1
Two component transcriptional regulator, LytTR family; COGs: COG3279 Response regulator of the LytR/AlgR family; InterPro IPR001789:IPR007492; KEGG: dfe:Dfer_1279 two component transcriptional regulator, LytTR family; PFAM: Signal transduction response regulator, receiver region; LytTr DNA-binding region; SMART: Signal transduction response regulator, receiver region; SPTR: Two component transcriptional regulator, LytTR family; IMG reference gene:2504769991; PFAM: Response regulator receiver domain; LytTr DNA-binding domain.
 
  
 0.807
AEE49194.1
Two component transcriptional regulator, LytTR family; COGs: COG3279 Response regulator of the LytR/AlgR family; InterPro IPR001789:IPR007492; KEGG: rbi:RB2501_05790 LytTr DNA-binding domain family protein; PFAM: Signal transduction response regulator, receiver region; LytTr DNA-binding region; SMART: Signal transduction response regulator, receiver region; SPTR: LytTr DNA-binding domain family protein; IMG reference gene:2504770660; PFAM: Response regulator receiver domain; LytTr DNA-binding domain.
 
  
 0.807
AEE49533.1
Two component transcriptional regulator, LytTR family; COGs: COG3279 Response regulator of the LytR/AlgR family; InterPro IPR001789:IPR007492; KEGG: dfe:Dfer_1279 two component transcriptional regulator, LytTR family; PFAM: Signal transduction response regulator, receiver region; LytTr DNA-binding region; SMART: Signal transduction response regulator, receiver region; SPTR: Two component transcriptional regulator, LytTR family; IMG reference gene:2504771005; PFAM: Response regulator receiver domain; LytTr DNA-binding domain.
 
  
 0.805
Your Current Organism:
Haliscomenobacter hydrossis
NCBI taxonomy Id: 760192
Other names: H. hydrossis DSM 1100, Haliscomenobacter hydrossis DSM 1100
Server load: low (22%) [HD]