| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AEE48085.1 | AEE48112.1 | Halhy_0172 | Halhy_0199 | COGs: COG2897 Rhodanese-related sulfurtransferase; InterPro IPR001763; KEGG: fjo:Fjoh_2623 rhodanese domain-containing protein; PFAM: Rhodanese-like; PRIAM: 3-mercaptopyruvate sulfurtransferase; SMART: Rhodanese-like; SPTR: Rhodanese domain protein; IMG reference gene:2504769524; PFAM: Rhodanese-like domain. | COGs: COG0436 Aspartate/tyrosine/aromatic aminotransferase; InterPro IPR004839; KEGG: lby:Lbys_2637 aminotransferase class I and II; PFAM: Aminotransferase, class I/II; PRIAM: Aspartate transaminase; SPTR: Aminotransferase class I and II; IMG reference gene:2504769551; PFAM: Aminotransferase class I and II. | 0.903 |
| AEE48085.1 | AEE52161.1 | Halhy_0172 | Halhy_4317 | COGs: COG2897 Rhodanese-related sulfurtransferase; InterPro IPR001763; KEGG: fjo:Fjoh_2623 rhodanese domain-containing protein; PFAM: Rhodanese-like; PRIAM: 3-mercaptopyruvate sulfurtransferase; SMART: Rhodanese-like; SPTR: Rhodanese domain protein; IMG reference gene:2504769524; PFAM: Rhodanese-like domain. | COGs: COG0626 Cystathionine beta-lyase/cystathionine gamma-synthase; InterPro IPR000277; KEGG: sli:Slin_5637 cystathionine gamma-lyase; PFAM: Cys/Met metabolism, pyridoxal phosphate-dependent enzyme; PRIAM: Cystathionine gamma-lyase; SPTR: Cystathionine beta-lyase; IMG reference gene:2504773703; PFAM: Cys/Met metabolism PLP-dependent enzyme. | 0.917 |
| AEE48085.1 | AEE53974.1 | Halhy_0172 | Halhy_6152 | COGs: COG2897 Rhodanese-related sulfurtransferase; InterPro IPR001763; KEGG: fjo:Fjoh_2623 rhodanese domain-containing protein; PFAM: Rhodanese-like; PRIAM: 3-mercaptopyruvate sulfurtransferase; SMART: Rhodanese-like; SPTR: Rhodanese domain protein; IMG reference gene:2504769524; PFAM: Rhodanese-like domain. | COGs: COG0436 Aspartate/tyrosine/aromatic aminotransferase; InterPro IPR004839; KEGG: phe:Phep_1507 aspartate aminotransferase; PFAM: Aminotransferase, class I/II; PRIAM: Aspartate transaminase; SPTR: Aspartate aminotransferase; IMG reference gene:2504775554; PFAM: Aminotransferase class I and II. | 0.903 |
| AEE48112.1 | AEE48085.1 | Halhy_0199 | Halhy_0172 | COGs: COG0436 Aspartate/tyrosine/aromatic aminotransferase; InterPro IPR004839; KEGG: lby:Lbys_2637 aminotransferase class I and II; PFAM: Aminotransferase, class I/II; PRIAM: Aspartate transaminase; SPTR: Aminotransferase class I and II; IMG reference gene:2504769551; PFAM: Aminotransferase class I and II. | COGs: COG2897 Rhodanese-related sulfurtransferase; InterPro IPR001763; KEGG: fjo:Fjoh_2623 rhodanese domain-containing protein; PFAM: Rhodanese-like; PRIAM: 3-mercaptopyruvate sulfurtransferase; SMART: Rhodanese-like; SPTR: Rhodanese domain protein; IMG reference gene:2504769524; PFAM: Rhodanese-like domain. | 0.903 |
| AEE48112.1 | AEE50854.1 | Halhy_0199 | Halhy_2990 | COGs: COG0436 Aspartate/tyrosine/aromatic aminotransferase; InterPro IPR004839; KEGG: lby:Lbys_2637 aminotransferase class I and II; PFAM: Aminotransferase, class I/II; PRIAM: Aspartate transaminase; SPTR: Aminotransferase class I and II; IMG reference gene:2504769551; PFAM: Aminotransferase class I and II. | COGs: COG0527 Aspartokinase; InterProIPR001048:IPR002912:IPR005106:IPR001342:IPR 001341; KEGG: chu:CHU_0073 bifunctional aspartokinase I/homeserine dehydrogenase I; PFAM: Homoserine dehydrogenase, catalytic; Aspartate/glutamate/uridylate kinase; Amino acid-binding ACT; Aspartate/homoserine dehydrogenase, NAD-binding; PRIAM: Aspartate kinase., Homoserine dehydrogenase; SPTR: Bifunctional protein: aspartokinase I; homoserine dehydrogenase; TIGRFAM: Aspartate kinase region; IMG reference gene:2504772364; PFAM: Homoserine dehydrogenase; Homoserine dehydrogenase, NAD binding domain; ACT dom [...] | 0.908 |
| AEE48112.1 | AEE52161.1 | Halhy_0199 | Halhy_4317 | COGs: COG0436 Aspartate/tyrosine/aromatic aminotransferase; InterPro IPR004839; KEGG: lby:Lbys_2637 aminotransferase class I and II; PFAM: Aminotransferase, class I/II; PRIAM: Aspartate transaminase; SPTR: Aminotransferase class I and II; IMG reference gene:2504769551; PFAM: Aminotransferase class I and II. | COGs: COG0626 Cystathionine beta-lyase/cystathionine gamma-synthase; InterPro IPR000277; KEGG: sli:Slin_5637 cystathionine gamma-lyase; PFAM: Cys/Met metabolism, pyridoxal phosphate-dependent enzyme; PRIAM: Cystathionine gamma-lyase; SPTR: Cystathionine beta-lyase; IMG reference gene:2504773703; PFAM: Cys/Met metabolism PLP-dependent enzyme. | 0.914 |
| AEE48112.1 | AEE53974.1 | Halhy_0199 | Halhy_6152 | COGs: COG0436 Aspartate/tyrosine/aromatic aminotransferase; InterPro IPR004839; KEGG: lby:Lbys_2637 aminotransferase class I and II; PFAM: Aminotransferase, class I/II; PRIAM: Aspartate transaminase; SPTR: Aminotransferase class I and II; IMG reference gene:2504769551; PFAM: Aminotransferase class I and II. | COGs: COG0436 Aspartate/tyrosine/aromatic aminotransferase; InterPro IPR004839; KEGG: phe:Phep_1507 aspartate aminotransferase; PFAM: Aminotransferase, class I/II; PRIAM: Aspartate transaminase; SPTR: Aspartate aminotransferase; IMG reference gene:2504775554; PFAM: Aminotransferase class I and II. | 0.918 |
| AEE49498.1 | AEE49983.1 | Halhy_1607 | Halhy_2098 | COGs: COG0031 Cysteine synthase; InterPro IPR001926; KEGG: cysteine synthase; PFAM: Pyridoxal phosphate-dependent enzyme, beta subunit; PRIAM: Cysteine synthase; SPTR: Cystathionine beta-synthase; IMG reference gene:2504770968; PFAM: Pyridoxal-phosphate dependent enzyme; TIGRFAM: cystathionine beta-synthase. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.935 |
| AEE49498.1 | AEE50854.1 | Halhy_1607 | Halhy_2990 | COGs: COG0031 Cysteine synthase; InterPro IPR001926; KEGG: cysteine synthase; PFAM: Pyridoxal phosphate-dependent enzyme, beta subunit; PRIAM: Cysteine synthase; SPTR: Cystathionine beta-synthase; IMG reference gene:2504770968; PFAM: Pyridoxal-phosphate dependent enzyme; TIGRFAM: cystathionine beta-synthase. | COGs: COG0527 Aspartokinase; InterProIPR001048:IPR002912:IPR005106:IPR001342:IPR 001341; KEGG: chu:CHU_0073 bifunctional aspartokinase I/homeserine dehydrogenase I; PFAM: Homoserine dehydrogenase, catalytic; Aspartate/glutamate/uridylate kinase; Amino acid-binding ACT; Aspartate/homoserine dehydrogenase, NAD-binding; PRIAM: Aspartate kinase., Homoserine dehydrogenase; SPTR: Bifunctional protein: aspartokinase I; homoserine dehydrogenase; TIGRFAM: Aspartate kinase region; IMG reference gene:2504772364; PFAM: Homoserine dehydrogenase; Homoserine dehydrogenase, NAD binding domain; ACT dom [...] | 0.865 |
| AEE49498.1 | AEE52157.1 | Halhy_1607 | Halhy_4313 | COGs: COG0031 Cysteine synthase; InterPro IPR001926; KEGG: cysteine synthase; PFAM: Pyridoxal phosphate-dependent enzyme, beta subunit; PRIAM: Cysteine synthase; SPTR: Cystathionine beta-synthase; IMG reference gene:2504770968; PFAM: Pyridoxal-phosphate dependent enzyme; TIGRFAM: cystathionine beta-synthase. | COGs: COG0620 Methionine synthase II (cobalamin-independent); InterPro IPR002629; KEGG: sli:Slin_5820 methionine synthase vitamin-B12 independent; PFAM: Methionine synthase, vitamin-B12 independent; SPTR: Methionine synthase vitamin-B12 independent; IMG reference gene:2504773699; PFAM: Cobalamin-independent synthase, Catalytic domain. | 0.909 |
| AEE49498.1 | AEE52161.1 | Halhy_1607 | Halhy_4317 | COGs: COG0031 Cysteine synthase; InterPro IPR001926; KEGG: cysteine synthase; PFAM: Pyridoxal phosphate-dependent enzyme, beta subunit; PRIAM: Cysteine synthase; SPTR: Cystathionine beta-synthase; IMG reference gene:2504770968; PFAM: Pyridoxal-phosphate dependent enzyme; TIGRFAM: cystathionine beta-synthase. | COGs: COG0626 Cystathionine beta-lyase/cystathionine gamma-synthase; InterPro IPR000277; KEGG: sli:Slin_5637 cystathionine gamma-lyase; PFAM: Cys/Met metabolism, pyridoxal phosphate-dependent enzyme; PRIAM: Cystathionine gamma-lyase; SPTR: Cystathionine beta-lyase; IMG reference gene:2504773703; PFAM: Cys/Met metabolism PLP-dependent enzyme. | 0.972 |
| AEE49498.1 | AEE54139.1 | Halhy_1607 | Halhy_6320 | COGs: COG0031 Cysteine synthase; InterPro IPR001926; KEGG: cysteine synthase; PFAM: Pyridoxal phosphate-dependent enzyme, beta subunit; PRIAM: Cysteine synthase; SPTR: Cystathionine beta-synthase; IMG reference gene:2504770968; PFAM: Pyridoxal-phosphate dependent enzyme; TIGRFAM: cystathionine beta-synthase. | COGs: COG0031 Cysteine synthase; InterPro IPR001926:IPR000644; KEGG: phe:Phep_1434 cysteine synthase; PFAM: Pyridoxal phosphate-dependent enzyme, beta subunit; Cystathionine beta-synthase, core; PRIAM: Cysteine synthase; SMART: Cystathionine beta-synthase, core; SPTR: Cystathionine beta-synthase; IMG reference gene:2504775728; PFAM: CBS domain; Pyridoxal-phosphate dependent enzyme; TIGRFAM: cystathionine beta-synthase. | 0.903 |
| AEE49983.1 | AEE49498.1 | Halhy_2098 | Halhy_1607 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | COGs: COG0031 Cysteine synthase; InterPro IPR001926; KEGG: cysteine synthase; PFAM: Pyridoxal phosphate-dependent enzyme, beta subunit; PRIAM: Cysteine synthase; SPTR: Cystathionine beta-synthase; IMG reference gene:2504770968; PFAM: Pyridoxal-phosphate dependent enzyme; TIGRFAM: cystathionine beta-synthase. | 0.935 |
| AEE49983.1 | AEE50854.1 | Halhy_2098 | Halhy_2990 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | COGs: COG0527 Aspartokinase; InterProIPR001048:IPR002912:IPR005106:IPR001342:IPR 001341; KEGG: chu:CHU_0073 bifunctional aspartokinase I/homeserine dehydrogenase I; PFAM: Homoserine dehydrogenase, catalytic; Aspartate/glutamate/uridylate kinase; Amino acid-binding ACT; Aspartate/homoserine dehydrogenase, NAD-binding; PRIAM: Aspartate kinase., Homoserine dehydrogenase; SPTR: Bifunctional protein: aspartokinase I; homoserine dehydrogenase; TIGRFAM: Aspartate kinase region; IMG reference gene:2504772364; PFAM: Homoserine dehydrogenase; Homoserine dehydrogenase, NAD binding domain; ACT dom [...] | 0.958 |
| AEE49983.1 | AEE52157.1 | Halhy_2098 | Halhy_4313 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | COGs: COG0620 Methionine synthase II (cobalamin-independent); InterPro IPR002629; KEGG: sli:Slin_5820 methionine synthase vitamin-B12 independent; PFAM: Methionine synthase, vitamin-B12 independent; SPTR: Methionine synthase vitamin-B12 independent; IMG reference gene:2504773699; PFAM: Cobalamin-independent synthase, Catalytic domain. | 0.968 |
| AEE49983.1 | AEE52161.1 | Halhy_2098 | Halhy_4317 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | COGs: COG0626 Cystathionine beta-lyase/cystathionine gamma-synthase; InterPro IPR000277; KEGG: sli:Slin_5637 cystathionine gamma-lyase; PFAM: Cys/Met metabolism, pyridoxal phosphate-dependent enzyme; PRIAM: Cystathionine gamma-lyase; SPTR: Cystathionine beta-lyase; IMG reference gene:2504773703; PFAM: Cys/Met metabolism PLP-dependent enzyme. | 0.963 |
| AEE49983.1 | AEE54139.1 | Halhy_2098 | Halhy_6320 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | COGs: COG0031 Cysteine synthase; InterPro IPR001926:IPR000644; KEGG: phe:Phep_1434 cysteine synthase; PFAM: Pyridoxal phosphate-dependent enzyme, beta subunit; Cystathionine beta-synthase, core; PRIAM: Cysteine synthase; SMART: Cystathionine beta-synthase, core; SPTR: Cystathionine beta-synthase; IMG reference gene:2504775728; PFAM: CBS domain; Pyridoxal-phosphate dependent enzyme; TIGRFAM: cystathionine beta-synthase. | 0.937 |
| AEE49983.1 | metG | Halhy_2098 | Halhy_2408 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | 0.926 |
| AEE50854.1 | AEE48112.1 | Halhy_2990 | Halhy_0199 | COGs: COG0527 Aspartokinase; InterProIPR001048:IPR002912:IPR005106:IPR001342:IPR 001341; KEGG: chu:CHU_0073 bifunctional aspartokinase I/homeserine dehydrogenase I; PFAM: Homoserine dehydrogenase, catalytic; Aspartate/glutamate/uridylate kinase; Amino acid-binding ACT; Aspartate/homoserine dehydrogenase, NAD-binding; PRIAM: Aspartate kinase., Homoserine dehydrogenase; SPTR: Bifunctional protein: aspartokinase I; homoserine dehydrogenase; TIGRFAM: Aspartate kinase region; IMG reference gene:2504772364; PFAM: Homoserine dehydrogenase; Homoserine dehydrogenase, NAD binding domain; ACT dom [...] | COGs: COG0436 Aspartate/tyrosine/aromatic aminotransferase; InterPro IPR004839; KEGG: lby:Lbys_2637 aminotransferase class I and II; PFAM: Aminotransferase, class I/II; PRIAM: Aspartate transaminase; SPTR: Aminotransferase class I and II; IMG reference gene:2504769551; PFAM: Aminotransferase class I and II. | 0.908 |
| AEE50854.1 | AEE49498.1 | Halhy_2990 | Halhy_1607 | COGs: COG0527 Aspartokinase; InterProIPR001048:IPR002912:IPR005106:IPR001342:IPR 001341; KEGG: chu:CHU_0073 bifunctional aspartokinase I/homeserine dehydrogenase I; PFAM: Homoserine dehydrogenase, catalytic; Aspartate/glutamate/uridylate kinase; Amino acid-binding ACT; Aspartate/homoserine dehydrogenase, NAD-binding; PRIAM: Aspartate kinase., Homoserine dehydrogenase; SPTR: Bifunctional protein: aspartokinase I; homoserine dehydrogenase; TIGRFAM: Aspartate kinase region; IMG reference gene:2504772364; PFAM: Homoserine dehydrogenase; Homoserine dehydrogenase, NAD binding domain; ACT dom [...] | COGs: COG0031 Cysteine synthase; InterPro IPR001926; KEGG: cysteine synthase; PFAM: Pyridoxal phosphate-dependent enzyme, beta subunit; PRIAM: Cysteine synthase; SPTR: Cystathionine beta-synthase; IMG reference gene:2504770968; PFAM: Pyridoxal-phosphate dependent enzyme; TIGRFAM: cystathionine beta-synthase. | 0.865 |
