Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
coaX-2Putative transcriptional acitvator, Baf family; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. (256 aa)    
Predicted Functional Partners:
panC
Pantothenate synthetase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family.
  
 
 0.952
AEE50593.1
Phosphopantothenoylcysteine decarboxylase/phosphopantothenate/cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family.
 
  
 0.932
coaD
Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family.
 
  
 0.928
coaX
Putative transcriptional acitvator, Baf family; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
  
  
 
0.927
AEE53903.1
Acyl carrier protein phosphodiesterase; COGs: COG3124 conserved hypothetical protein; InterPro IPR007431; KEGG: gfo:GFO_2057 hypothetical protein; PFAM: Acyl carrier protein phosphodiesterase; SPTR: Putative uncharacterized protein; IMG reference gene:2504775483; PFAM: Protein of unknown function, DUF479.
     
  0.900
AEE52193.1
Acylphosphatase; COGs: COG0068 Hydrogenase maturation factor; HAMAP: Acylphosphatase; InterPro IPR001792:IPR011125:IPR006070:IPR004421; KEGG: sli:Slin_3880 (NiFe) hydrogenase maturation protein HypF; PFAM: Sua5/YciO/YrdC, N-terminal; Acylphosphatase-like; Zinc finger, HypF-type; SPTR: (NiFe) hydrogenase maturation protein HypF; TIGRFAM: Hydrogenase maturation factor, HypF-type; IMG reference gene:2504773735; PFAM: HypF finger; yrdC domain; Acylphosphatase; TIGRFAM: [NiFe] hydrogenase maturation protein HypF.
       0.762
panD
Aspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
  
  
 0.630
AEE52191.1
Peptidase S8 and S53 subtilisin kexin sedolisin; COGs: COG1404 Subtilisin-like serine protease; InterPro IPR000209:IPR007730; KEGG: ava:Ava_2140 peptidase S8/S53 subtilisin kexin sedolisin; PFAM: Peptidase S8/S53, subtilisin/kexin/sedolisin; Sporulation/cell division region, bacteria; SPTR: Subtilase family peptidase; IMG reference gene:2504773733; PFAM: Sporulation related domain; Subtilase family.
       0.503
AEE51434.1
COGs: COG0340 Biotin-(acetyl-CoA carboxylase) ligase; InterPro IPR004408:IPR004143; KEGG: sli:Slin_3003 biotin/acetyl-CoA-carboxylase ligase; PFAM: Biotin/lipoate A/B protein ligase; SPTR: Biotin-acetyl-CoA-carboxylase ligase; TIGRFAM: Biotin--acetyl-CoA-carboxylase ligase; IMG reference gene:2504772961; PFAM: Biotin/lipoate A/B protein ligase family; TIGRFAM: birA, biotin-[acetyl-CoA-carboxylase] ligase region.
 
    0.446
AEE52194.1
KEGG: cse:Cseg_0880 putative dehydrogenase; SPTR: Putative uncharacterized protein; IMG reference gene:2504773736.
       0.401
Your Current Organism:
Haliscomenobacter hydrossis
NCBI taxonomy Id: 760192
Other names: H. hydrossis DSM 1100, Haliscomenobacter hydrossis DSM 1100
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.