Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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AEE52196.1Hydrogenase expression/formation protein HypE; COGs: COG0309 Hydrogenase maturation factor; InterPro IPR000728:IPR010918:IPR011854; KEGG: sli:Slin_3877 hydrogenase expression/formation protein HypE; PFAM: AIR synthase related protein, C-terminal; AIR synthase related protein; SPTR: Hydrogenase expression/formation protein HypE; TIGRFAM: Hydrogenase expression/formation protein HypE; IMG reference gene:2504773738; PFAM: AIR synthase related protein, N-terminal domain; AIR synthase related protein, C-terminal domain; TIGRFAM: hydrogenase expression/formation protein HypE. (345 aa)    
Predicted Functional Partners:
AEE52195.1
Hydrogenase expression/formation protein HypD; COGs: COG0409 Hydrogenase maturation factor; InterPro IPR002780; KEGG: sli:Slin_3878 hydrogenase expression/formation protein HypD; PFAM: Hydrogenase formation HypD protein; SPTR: Hydrogenase expression/formation protein HypD; TIGRFAM: Hydrogenase formation HypD protein; IMG reference gene:2504773737; PFAM: Hydrogenase formation hypA family; TIGRFAM: hydrogenase expression/formation protein HypD.
 
 
 0.997
AEE52193.1
Acylphosphatase; COGs: COG0068 Hydrogenase maturation factor; HAMAP: Acylphosphatase; InterPro IPR001792:IPR011125:IPR006070:IPR004421; KEGG: sli:Slin_3880 (NiFe) hydrogenase maturation protein HypF; PFAM: Sua5/YciO/YrdC, N-terminal; Acylphosphatase-like; Zinc finger, HypF-type; SPTR: (NiFe) hydrogenase maturation protein HypF; TIGRFAM: Hydrogenase maturation factor, HypF-type; IMG reference gene:2504773735; PFAM: HypF finger; yrdC domain; Acylphosphatase; TIGRFAM: [NiFe] hydrogenase maturation protein HypF.
 
 
 0.984
AEE49703.1
Hydrogenase assembly chaperone hypC/hupF; COGs: COG0298 Hydrogenase maturation factor; InterPro IPR001109; KEGG: sli:Slin_3879 hydrogenase assembly chaperone HypC/HupF; PFAM: Hydrogenase expression/formation protein, HupF/HypC; SPTR: Hydrogenase assembly chaperone hypC/hupF; TIGRFAM: Hydrogenase expression/formation protein, HupF/HypC; IMG reference gene:2504771179; PFAM: HupF/HypC family; TIGRFAM: hydrogenase assembly chaperone HypC/HupF.
 
 
 0.975
AEE49704.1
Hydrogenase accessory protein HypB; COGs: COG0378 Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase; InterPro IPR004392:IPR003495; KEGG: fjo:Fjoh_3904 hydrogenase accessory protein HypB; PFAM: Cobalamin (vitamin B12) biosynthesis CobW-like; SPTR: Hydrogenase accessory protein HypB; TIGRFAM: Hydrogenase accessory protein HypB; IMG reference gene:2504771180; PFAM: CobW/HypB/UreG, nucleotide-binding domain; TIGRFAM: hydrogenase accessory protein HypB.
 
  
 0.871
hypA
Hydrogenase expression/synthesis HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
 
  
 0.851
AEE49707.1
COGs: COG0374 Ni Fe-hydrogenase I large subunit; InterPro IPR001501; KEGG: fjo:Fjoh_3907 nickel-dependent hydrogenase, large subunit; PFAM: Nickel-dependent hydrogenase, large subunit; PRIAM: Cytochrome-c3 hydrogenase; SPTR: Nickel-dependent hydrogenase large subunit; IMG reference gene:2504771183; PFAM: Nickel-dependent hydrogenase.
 
   
 0.765
AEE52197.1
High-affinity nickel-transporter; InterPro IPR011541; KEGG: sli:Slin_3875 putative urease accessory protein; PFAM: Nickel/cobalt transporter, high-affinity; SPTR: High-affinity nickel-transporter; IMG reference gene:2504773739; PFAM: High-affinity nickel-transport protein.
 
     0.730
AEE49706.1
COGs: COG1740 Ni Fe-hydrogenase I small subunit; InterPro IPR001821:IPR006311:IPR006137; KEGG: fjo:Fjoh_3906 hydrogenase (NiFe) small subunit HydA; PFAM: NADH:ubiquinone oxidoreductase-like, 20kDa subunit; PRIAM: Hydrogenase (acceptor); SPTR: Hydrogenase (NiFe) small subunit HydA; TIGRFAM: [Ni-Fe]-hydrogenase, small subunit; Twin-arginine translocation pathway, signal sequence; IMG reference gene:2504771182; PFAM: NADH ubiquinone oxidoreductase, 20 Kd subunit; TIGRFAM: hydrogenase (NiFe) small subunit (hydA); Tat (twin-arginine translocation) pathway signal sequence.
 
   
 0.715
AEE49709.1
COGs: COG0680 Ni Fe-hydrogenase maturation factor; InterPro IPR000671; KEGG: fjo:Fjoh_3909 hydrogenase maturation protease; PFAM: Peptidase A31, hydrogen uptake protein; SPTR: Hydrogenase maturation protease; TIGRFAM: Peptidase A31, hydrogen uptake protein; IMG reference gene:2504771185; PFAM: Hydrogenase maturation protease; TIGRFAM: hydrogenase maturation protease.
 
   
 0.701
AEE54329.1
COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterProIPR011895:IPR002880:IPR019752:IPR019456:IPR 001450:IPR011766; KEGG: mca:MCA0769 pyruvate ferredoxin/flavodoxin oxidoreductase family protein; PFAM: Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal; Pyruvate/ketoisovalerate oxidoreductase; Pyruvate-flavodoxin oxidoreductase, EKR domain; 4Fe-4S ferredoxin, iron-sulphur binding, subgroup; Thiamine pyrophosphate enzyme, C-terminal TPP-binding; PRIAM: Pyruvate dehydrogenase (NADP(+)); SPTR: Pyruvate ferredoxin/fla [...]
     
 0.478
Your Current Organism:
Haliscomenobacter hydrossis
NCBI taxonomy Id: 760192
Other names: H. hydrossis DSM 1100, Haliscomenobacter hydrossis DSM 1100
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