Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AEE52198.1Transcriptional regulator, DeoR family; COGs: COG1349 Transcriptional regulators of sugar metabolism; InterPro IPR001034:IPR014036; KEGG: cpi:Cpin_6809 transcriptional regulator, DeoR family; PFAM: HTH transcriptional regulator, DeoR; HTH transcriptional regulator, DeoR N-terminal; SMART: HTH transcriptional regulator, DeoR N-terminal; SPTR: Transcriptional regulator, DeoR family; IMG reference gene:2504773740; PFAM: Bacterial regulatory proteins, deoR family; DeoR-like helix-turn-helix domain. (249 aa)    
Predicted Functional Partners:
AEE50677.1
GCN5-related N-acetyltransferase; COGs: COG1042 Acyl-CoA synthetase (NDP forming); InterPro IPR003781:IPR013650:IPR000182; KEGG: deh:cbdb_A1077 acetyl-CoA synthetase; PFAM: GCN5-related N-acetyltransferase; ATP-grasp fold, succinyl-CoA synthetase-type; CoA-binding; SPTR: Acetyltransferase, GNAT family; IMG reference gene:2504772183; PFAM: Acetyltransferase (GNAT) family.
    
   0.684
AEE51094.1
COGs: COG0578 Glycerol-3-phosphate dehydrogenase; InterPro IPR006076; KEGG: dfe:Dfer_2005 FAD dependent oxidoreductase; PFAM: FAD dependent oxidoreductase; PRIAM: Glycerol-3-phosphate dehydrogenase; SPTR: FAD dependent oxidoreductase; IMG reference gene:2504772614; PFAM: FAD dependent oxidoreductase; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.
 
  
 0.593
murQ
N-acetylmuramic acid 6-phosphate etherase; Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D- lactate.
     
 0.540
glpK
Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family.
 
  
 0.494
AEE49200.1
COGs: COG1129 ABC-type sugar transport system ATPase component; InterPro IPR003439:IPR003593; KEGG: tnp:Tnap_0914 inner-membrane translocator; PFAM: ABC transporter-like; PRIAM: Monosaccharide-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: Inner-membrane translocator; IMG reference gene:2504770666; PFAM: ABC transporter.
 
   
 0.483
AEE51180.1
Major intrinsic protein; COGs: COG0580 Glycerol uptake facilitator and related permease (Major Intrinsic Protein Family); InterPro IPR000425; KEGG: sli:Slin_5936 major intrinsic protein; PFAM: Major intrinsic protein; SPTR: Major intrinsic protein; IMG reference gene:2504772701; PFAM: Major intrinsic protein; TIGRFAM: MIP family channel proteins; Belongs to the MIP/aquaporin (TC 1.A.8) family.
 
  
 0.461
AEE49044.1
Rhamnulose-1-phosphate aldolase/alcohol dehydrogenase; COGs: COG3347 conserved hypothetical protein; InterPro IPR001303:IPR002198:IPR013454; KEGG: sli:Slin_1802 rhamnulose-1-phosphate aldolase/alcohol dehydrogenase; PFAM: Short-chain dehydrogenase/reductase SDR; Class II aldolase/adducin, N-terminal; PRIAM: 3-oxoacyl-[acyl-carrier-protein] reductase; SPTR: Rhamnulose-1-phosphate aldolase/alcohol dehydrogenase; TIGRFAM: Bifunctional rhamnulose-1-phosphate aldolase/alcohol dehydrogenase; IMG reference gene:2504770507; PFAM: Class II Aldolase and Adducin N-terminal domain; short chain deh [...]
     
 0.441
AEE49199.1
ABC-type transporter, integral membrane subunit; COGs: COG1172 Ribose/xylose/arabinose/galactoside ABC-type transport systems permease components; InterPro IPR001851; KEGG: aac:Aaci_2903 inner-membrane translocator; PFAM: Bacterial inner-membrane translocator; SPTR: Monosaccharide-transporting ATPase; IMG reference gene:2504770665; PFAM: Branched-chain amino acid transport system / permease component.
 
   
 0.435
AEE52199.1
ATPase BadF/BadG/BcrA/BcrD type; COGs: COG2971 N-acetylglucosamine kinase; InterPro IPR002731; KEGG: bfs:BF0368 hypothetical protein; PFAM: ATPase, BadF/BadG/BcrA/BcrD type; SPTR: Putative uncharacterized protein; IMG reference gene:2504773741; PFAM: BadF/BadG/BcrA/BcrD ATPase family.
  
    0.421
Your Current Organism:
Haliscomenobacter hydrossis
NCBI taxonomy Id: 760192
Other names: H. hydrossis DSM 1100, Haliscomenobacter hydrossis DSM 1100
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.