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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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AEE52208.1Histidine kinase; COGs: COG3292 periplasmic ligand-binding sensor domain; InterPro IPR011110:IPR011123:IPR011712:IPR003594; KEGG: sli:Slin_5621 PAS/PAC sensor signal transduction histidine kinase; PFAM: ATP-binding region, ATPase-like; Two component regulator three Y; Two component regulator propeller; Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor region; SPTR: Two-component system sensor histidine kinase; IMG reference gene:2504773751; PFAM: Histidine kinase; Y_Y_Y domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Two component regul [...] (1160 aa)    
Predicted Functional Partners:
AEE52207.1
Two component transcriptional regulator, LuxR family; COGs: COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; InterPro IPR001789:IPR000792; KEGG: two component transcriptional regulator, LuxR family; PFAM: Signal transduction response regulator, receiver region; Transcription regulator LuxR, C-terminal; SMART: Signal transduction response regulator, receiver region; Transcription regulator LuxR, C-terminal; SPTR: Two-component response regulator; IMG reference gene:2504773750; PFAM: Response regulator receiver domain; Bacterial regulatory [...]
 
   0.859
AEE49987.1
KEGG: sli:Slin_0921 histidine kinase; SPTR: Histidine kinase; IMG reference gene:2504771469; PFAM: Two component regulator propeller.
  
 
 0.791
AEE52415.1
Two component transcriptional regulator, LuxR family; COGs: COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; InterPro IPR001789:IPR000792; KEGG: cpi:Cpin_4160 two component transcriptional regulator, LuxR family; PFAM: Signal transduction response regulator, receiver region; Transcription regulator LuxR, C-terminal; SMART: Signal transduction response regulator, receiver region; Transcription regulator LuxR, C-terminal; SPTR: Two component transcriptional regulator, LuxR family; IMG reference gene:2504773968; PFAM: Response regulator rece [...]
 
   0.560
AEE49351.1
Two component transcriptional regulator, LuxR family; COGs: COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; InterPro IPR001789:IPR000792; KEGG: phe:Phep_1616 response regulator receiver; PFAM: Signal transduction response regulator, receiver region; Transcription regulator LuxR, C-terminal; SMART: Signal transduction response regulator, receiver region; Transcription regulator LuxR, C-terminal; SPTR: Transcriptional regulator, LuxR family protein; IMG reference gene:2504770818; PFAM: Response regulator receiver domain; Bacterial regulato [...]
 
   0.541
AEE50837.1
Adenylate/guanylate cyclase; COGs: COG0642 Signal transduction histidine kinase; InterProIPR003661:IPR003594:IPR001789:IPR001054:IPR 011110:IPR011123; KEGG: ter:Tery_2729 adenylate/guanylate cyclase; PFAM: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; Two component regulator three Y; Two component regulator propeller; Signal transduction response regulator, receiver region; Adenylyl cyclase class-3/4/guanylyl cyclase; SMART: Signal transduction response regulator, receiver region; ATP-binding region, ATPase-like; [...]
 
 
0.519
AEE48892.1
Two component transcriptional regulator, LuxR family; COGs: COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; InterPro IPR001789:IPR000792; KEGG: cpi:Cpin_4160 two component transcriptional regulator, LuxR family; PFAM: Signal transduction response regulator, receiver region; Transcription regulator LuxR, C-terminal; SMART: Transcription regulator LuxR, C-terminal; Signal transduction response regulator, receiver region; SPTR: Two component transcriptional regulator, LuxR family; IMG reference gene:2504770353; PFAM: Response regulator rece [...]
 
   0.516
AEE54221.1
COGs: COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; InterPro IPR001789; KEGG: cpi:Cpin_3102 two component transcriptional regulator, LuxR family; PFAM: Signal transduction response regulator, receiver region; SMART: Signal transduction response regulator, receiver region; SPTR: Two component transcriptional regulator, LuxR family; IMG reference gene:2504775810; PFAM: Response regulator receiver domain.
 
   0.513
AEE53333.1
Two component transcriptional regulator, LuxR family; COGs: COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; InterPro IPR001789:IPR000792; KEGG: cac:CA_C0240 response regulator; PFAM: Signal transduction response regulator, receiver region; Transcription regulator LuxR, C-terminal; SMART: Signal transduction response regulator, receiver region; Transcription regulator LuxR, C-terminal; SPTR: Two component transcriptional regulator, LuxR family; IMG reference gene:2504774906; PFAM: Response regulator receiver domain; Bacterial regulatory p [...]
 
   0.507
AEE52206.1
Hypothetical protein; KEGG: lbc:LACBIDRAFT_382412 tectonin 2; SPTR: Tectonin 2; IMG reference gene:2504773749.
       0.492
AEE50416.1
Two component transcriptional regulator, LuxR family; COGs: COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; InterPro IPR001789:IPR000792; KEGG: dfe:Dfer_0722 two component transcriptional regulator, LuxR family; PFAM: Signal transduction response regulator, receiver region; Transcription regulator LuxR, C-terminal; SMART: Signal transduction response regulator, receiver region; Transcription regulator LuxR, C-terminal; SPTR: Two-component response regulator; IMG reference gene:2504771912; PFAM: Response regulator receiver domain; Bacteri [...]
 
   0.489
Your Current Organism:
Haliscomenobacter hydrossis
NCBI taxonomy Id: 760192
Other names: H. hydrossis DSM 1100, Haliscomenobacter hydrossis DSM 1100
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