Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
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AEE52241.1InterPro IPR013096; KEGG: dfe:Dfer_2840 cupin 2 conserved barrel domain protein; PFAM: Cupin 2, conserved barrel; SPTR: Cupin 2 conserved barrel domain protein; IMG reference gene:2504773784; PFAM: Cupin domain. (117 aa)    
Predicted Functional Partners:
kduI
4-deoxy-L-threo-5-hexosulose-uronateketol- isomerase; Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate. Belongs to the KduI family.
 
  
 0.963
AEE52240.1
Pectinesterase; COGs: COG4677 Pectin methylesterase; InterPro IPR000070; KEGG: ote:Oter_4090 pectinesterase; PFAM: Pectinesterase, catalytic; SPTR: Pectinesterase; IMG reference gene:2504773783; PFAM: Pectinesterase.
 
     0.811
AEE52239.1
Glycosyl hydrolase family 88; COGs: COG4225 unsaturated glucuronyl hydrolase involved in regulation of surface properties and related protein; InterPro IPR010905; KEGG: dfe:Dfer_2841 glycosyl hydrolase family 88; PFAM: Glycosyl hydrolase, family 88; SPTR: Glycosyl hydrolase family 88; IMG reference gene:2504773782; PFAM: Glycosyl Hydrolase Family 88.
 
     0.794
AEE52242.1
Tagaturonate reductase; COGs: COG0246 Mannitol-1-phosphate/altronate dehydrogenase; InterPro IPR013131:IPR013118; KEGG: sli:Slin_1247 mannitol dehydrogenase domain protein; PFAM: Mannitol dehydrogenase, C-terminal; Mannitol dehydrogenase, N-terminal; PRIAM: Tagaturonate reductase; SPTR: Mannitol dehydrogenase domain protein; IMG reference gene:2504773785; PFAM: Mannitol dehydrogenase C-terminal domain; Mannitol dehydrogenase Rossmann domain.
 
   
 0.790
AEE52243.1
COGs: COG2721 Altronate dehydratase; InterPro IPR007392; KEGG: sli:Slin_4785 altronate dehydratase; PFAM: D-galactarate dehydratase/Altronate hydrolase, C-terminal; PRIAM: Altronate dehydratase; SPTR: Altronate dehydratase; IMG reference gene:2504773786; PFAM: SAF domain; D-galactarate dehydratase / Altronate hydrolase, C terminus.
 
     0.733
AEE52245.1
PfkB domain protein; COGs: COG0524 Sugar kinase ribokinase family; InterPro IPR011611; KEGG: pdi:BDI_3186 putative gluconate kinase; PFAM: Carbohydrate/purine kinase; SPTR: KHG/KDPG family aldolase/carbohydrate kinase, PfkB family; IMG reference gene:2504773788; PFAM: pfkB family carbohydrate kinase.
 
   
 0.610
uxaC
COGs: COG1904 Glucuronate isomerase; HAMAP: Uronate isomerase; InterPro IPR003766; KEGG: sli:Slin_4786 glucuronate isomerase; PFAM: Uronate isomerase; PRIAM: Glucuronate isomerase; SPTR: Uronate isomerase 2; IMG reference gene:2504773787; PFAM: Glucuronate isomerase.
 
     0.558
AEE52225.1
2-deoxy-D-gluconate 3-dehydrogenase; COGs: COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase); InterPro IPR002198; KEGG: sli:Slin_3404 short-chain dehydrogenase/reductase SDR; PFAM: Short-chain dehydrogenase/reductase SDR; PRIAM: 2-deoxy-D-gluconate 3-dehydrogenase; SPTR: Short-chain dehydrogenase/reductase SDR; IMG reference gene:2504773768; PFAM: short chain dehydrogenase; TIGRFAM: 2-deoxy-D-gluconate 3-dehydrogenase.
  
     0.555
AEE52246.1
KDPG and KHG aldolase; COGs: COG0800 2-keto-3-deoxy-6-phosphogluconate aldolase; InterPro IPR000887; KEGG: sli:Slin_1245 KDPG and KHG aldolase; PFAM: KDPG/KHG aldolase; SPTR: KDPG and KHG aldolase; IMG reference gene:2504773789; PFAM: KDPG and KHG aldolase; TIGRFAM: Entner-Doudoroff aldolase.
 
   
 0.505
AEE52247.1
Major facilitator superfamily MFS_1; COGs: COG2271 Sugar phosphate permease; InterPro IPR011701; KEGG: lby:Lbys_1615 major facilitator superfamily mfs_1; PFAM: Major facilitator superfamily MFS-1; SPTR: Major facilitator superfamily MFS_1; IMG reference gene:2504773790; PFAM: Major Facilitator Superfamily.
 
     0.502
Your Current Organism:
Haliscomenobacter hydrossis
NCBI taxonomy Id: 760192
Other names: H. hydrossis DSM 1100, Haliscomenobacter hydrossis DSM 1100
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