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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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[Homology]
Score
AEE52246.1KDPG and KHG aldolase; COGs: COG0800 2-keto-3-deoxy-6-phosphogluconate aldolase; InterPro IPR000887; KEGG: sli:Slin_1245 KDPG and KHG aldolase; PFAM: KDPG/KHG aldolase; SPTR: KDPG and KHG aldolase; IMG reference gene:2504773789; PFAM: KDPG and KHG aldolase; TIGRFAM: Entner-Doudoroff aldolase. (221 aa)    
Predicted Functional Partners:
AEE52245.1
PfkB domain protein; COGs: COG0524 Sugar kinase ribokinase family; InterPro IPR011611; KEGG: pdi:BDI_3186 putative gluconate kinase; PFAM: Carbohydrate/purine kinase; SPTR: KHG/KDPG family aldolase/carbohydrate kinase, PfkB family; IMG reference gene:2504773788; PFAM: pfkB family carbohydrate kinase.
 
 
 0.992
AEE54038.1
COGs: COG1052 Lactate dehydrogenase and related dehydrogenase; InterPro IPR006139:IPR006140; KEGG: dfe:Dfer_4232 D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region; PRIAM: Phosphoglycerate dehydrogenase; SPTR: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; IMG reference gene:2504775625; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain.
    
  0.905
AEE50185.1
Glyceraldehyde-3-phosphate dehydrogenase (NADP(+)); COGs: COG1012 NAD-dependent aldehyde dehydrogenase; InterPro IPR015590; KEGG: lby:Lbys_2607 aldehyde dehydrogenase; PFAM: Aldehyde dehydrogenase; PRIAM: Glyceraldehyde-3-phosphate dehydrogenase (NADP(+)); SPTR: Aldehyde Dehydrogenase; IMG reference gene:2504771674; PFAM: Aldehyde dehydrogenase family.
    
 0.904
AEE51215.1
Alanine--glyoxylate transaminase; COGs: COG0160 4-aminobutyrate aminotransferase and related aminotransferase; InterPro IPR005814; KEGG: sus:Acid_7662 aminotransferase; PFAM: Aminotransferase class-III; PRIAM: Alanine--glyoxylate transaminase; SPTR: Aminotransferase; IMG reference gene:2504772737; PFAM: Aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
     
  0.900
uxaC
COGs: COG1904 Glucuronate isomerase; HAMAP: Uronate isomerase; InterPro IPR003766; KEGG: sli:Slin_4786 glucuronate isomerase; PFAM: Uronate isomerase; PRIAM: Glucuronate isomerase; SPTR: Uronate isomerase 2; IMG reference gene:2504773787; PFAM: Glucuronate isomerase.
 
   
 0.895
pgi
COGs: COG0166 Glucose-6-phosphate isomerase; HAMAP: Phosphoglucose isomerase (PGI); InterPro IPR001672; KEGG: vcj:VCD_001250 glucose-6-phosphate isomerase; PFAM: Phosphoglucose isomerase (PGI); PRIAM: Glucose-6-phosphate isomerase; SPTR: Glucose-6-phosphate isomerase; IMG reference gene:2504775370; PFAM: Phosphoglucose isomerase; Belongs to the GPI family.
  
 
 0.865
AEE48570.1
COGs: COG0057 Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase; InterPro IPR020828:IPR020829:IPR006424; KEGG: sli:Slin_1998 glyceraldehyde-3-phosphate dehydrogenase, type I; PFAM: Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain; Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain; PRIAM: Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating); SPTR: Glyceraldehyde-3-phosphate dehydrogenase, type I; TIGRFAM: Glyceraldehyde-3-phosphate dehydrogenase, type I; IMG reference gene:2504770018; PFAM: Glyceraldehyde 3-phosphate dehydrogenase [...]
  
 
 0.864
AEE50870.1
COGs: COG0469 Pyruvate kinase; InterPro IPR015793:IPR015794:IPR001697; KEGG: cpi:Cpin_2321 pyruvate kinase; PFAM: Pyruvate kinase, barrel; Pyruvate kinase, alpha/beta; PRIAM: Pyruvate kinase; SPTR: Pyruvate kinase; TIGRFAM: Pyruvate kinase; IMG reference gene:2504772381; PFAM: Pyruvate kinase, barrel domain; Pyruvate kinase, alpha/beta domain; TIGRFAM: pyruvate kinase; Belongs to the pyruvate kinase family.
    
 0.840
AEE53641.1
COGs: COG0469 Pyruvate kinase; InterPro IPR015793; KEGG: pyruvate kinase; PFAM: Pyruvate kinase, barrel; PRIAM: Pyruvate kinase; SPTR: Pyruvate kinase; IMG reference gene:2504775216; PFAM: Pyruvate kinase, barrel domain; Belongs to the pyruvate kinase family.
    
 0.840
tpiA
Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
     
 0.839
Your Current Organism:
Haliscomenobacter hydrossis
NCBI taxonomy Id: 760192
Other names: H. hydrossis DSM 1100, Haliscomenobacter hydrossis DSM 1100
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