Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AEE52327.1Transcriptional regulator, AraC family; COGs: COG2207 AraC-type DNA-binding domain-containing protein; InterPro IPR000005:IPR018060; KEGG: rmr:Rmar_2599 transcriptional regulator, AraC family; PFAM: Helix-turn-helix, AraC type; SMART: Helix-turn-helix, AraC domain; SPTR: RegA, putative; IMG reference gene:2504773874; PFAM: Bacterial regulatory helix-turn-helix proteins, AraC family. (362 aa)    
Predicted Functional Partners:
AEE49242.1
Transcriptional regulator, AraC family; COGs: COG2207 AraC-type DNA-binding domain-containing protein; InterPro IPR000005:IPR018060; KEGG: zpr:ZPR_3198 sugar-binding sensor histidine kinase/response regulator hybrid; PFAM: Helix-turn-helix, AraC type; SMART: Helix-turn-helix, AraC domain; SPTR: Putative uncharacterized protein; IMG reference gene:2504770708; PFAM: Bacterial regulatory helix-turn-helix proteins, AraC family.
  
     0.672
AEE53659.1
Transcriptional regulator, AraC family; COGs: COG2207 AraC-type DNA-binding domain-containing protein; InterPro IPR018060:IPR000005; KEGG: transcriptional regulator, AraC family; PFAM: Helix-turn-helix, AraC type; SMART: Helix-turn-helix, AraC domain; SPTR: Transcriptional regulator; IMG reference gene:2504775234.
  
     0.630
AEE52328.1
InterPro IPR011659; KEGG: mxa:MXAN_7077 WD-40-like beta propeller repeat-containing protein; PFAM: WD40-like Beta Propeller; SPTR: WD40-like beta propeller repeat protein; IMG reference gene:2504773875; PFAM: WD40-like Beta Propeller Repeat.
       0.552
AEE53234.1
Transcriptional regulator, AraC family; COGs: COG4977 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain; InterPro IPR000005:IPR018060; KEGG: hau:Haur_0091 AraC family transcriptional regulator; PFAM: Helix-turn-helix, AraC type; SMART: Helix-turn-helix, AraC domain; SPTR: Transcriptional regulator, AraC family; IMG reference gene:2504774807; PFAM: Bacterial regulatory helix-turn-helix proteins, AraC family.
  
   0.491
AEE50539.1
Transcriptional regulator, AraC family; COGs: COG2207 AraC-type DNA-binding domain-containing protein; InterPro IPR000005:IPR018060; KEGG: cpi:Cpin_5626 transcriptional regulator, AraC family; PFAM: Helix-turn-helix, AraC type; SMART: Helix-turn-helix, AraC domain; SPTR: Transcriptional regulator, AraC family protein; IMG reference gene:2504772042; PFAM: Bacterial regulatory helix-turn-helix proteins, AraC family; AraC-like ligand binding domain.
  
     0.477
AEE52329.1
KEGG: lby:Lbys_3497 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504773876.
 
     0.472
AEE53667.1
Transcriptional regulator, AraC family; COGs: COG2207 AraC-type DNA-binding domain-containing protein; InterPro IPR018060:IPR000005; KEGG: cyc:PCC7424_1148 transcriptional regulator, AraC family; PFAM: Helix-turn-helix, AraC type; SMART: Helix-turn-helix, AraC domain; SPTR: Transcriptional regulator, AraC family; IMG reference gene:2504775242; PFAM: Bacterial regulatory helix-turn-helix proteins, AraC family.
  
     0.468
AEE48462.1
Transcriptional regulator, AraC family; COGs: COG2207 AraC-type DNA-binding domain-containing protein; InterPro IPR000005:IPR018060; KEGG: fjo:Fjoh_4826 helix-turn-helix domain-containing protein; PFAM: Helix-turn-helix, AraC type; SMART: Helix-turn-helix, AraC domain; SPTR: AraC family transcriptional regulator; IMG reference gene:2504769908; PFAM: Bacterial regulatory helix-turn-helix proteins, AraC family.
  
     0.450
AEE48588.1
Transcriptional regulator, AraC family; COGs: COG4977 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain; InterPro IPR000005:IPR018060; KEGG: bth:BT_2897 two-component system sensor histidine kinase/response regulator, hybrid ('one-component system'); PFAM: Helix-turn-helix, AraC type; SMART: Helix-turn-helix, AraC domain; SPTR: Transcriptional regulator with PAS/PAC sensors, AraC family; IMG reference gene:2504770038; PFAM: Bacterial regulatory helix-turn-helix proteins, AraC family.
  
   0.445
AEE53190.1
Transcriptional regulator, AraC family; COGs: COG2207 AraC-type DNA-binding domain-containing protein; InterPro IPR000005:IPR018060; KEGG: cpi:Cpin_7131 transcriptional regulator, AraC family; PFAM: Helix-turn-helix, AraC type; SMART: Helix-turn-helix, AraC domain; SPTR: Transcriptional regulator, AraC family; IMG reference gene:2504774763; PFAM: Bacterial regulatory helix-turn-helix proteins, AraC family.
  
     0.444
Your Current Organism:
Haliscomenobacter hydrossis
NCBI taxonomy Id: 760192
Other names: H. hydrossis DSM 1100, Haliscomenobacter hydrossis DSM 1100
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.