Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AEE52436.1Nitrate reductase., Nitrite reductase (NAD(P)H); COGs: COG3383 Uncharacterized anaerobic dehydrogenase; InterProIPR006963:IPR006656:IPR006657:IPR013027:IPR 007419; KEGG: nitrate reductase, nitrite reductase (nad(p)h); PFAM: Molybdopterin oxidoreductase; Molybdopterin oxidoreductase Fe4S4 region; Molydopterin dinucleotide-binding region; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; BFD-like [2Fe-2S]-binding region; PRIAM: Nitrate reductase., Nitrite reductase (NAD(P)H); SPTR: Assimilatory nitrate reductase (NADH) beta subunit / assimilatory nitrate reductase (NADH) alpha [...] (1222 aa)    
Predicted Functional Partners:
AEE52098.1
COGs: COG2146 Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenase; InterPro IPR017941:IPR012748; KEGG: assimilatory nitrite reductase (nad(p)h) small subunit; PFAM: Rieske [2Fe-2S] iron-sulphur domain; SPTR: Nitrite reductase (NAD(P)H), small subunit; TIGRFAM: Nitrite reductase [NAD(P)H] large subunit, NirD; IMG reference gene:2504773640; PFAM: Rieske [2Fe-2S] domain; TIGRFAM: nitrite reductase [NAD(P)H], small subunit.
 
 
 0.994
AEE52437.1
InterPro IPR004039; KEGG: rubredoxin-type fe(cys)4 protein; PFAM: Rubredoxin-type Fe(Cys)4 protein; SPTR: Putative rubredoxin; IMG reference gene:2504773992; PFAM: Rubredoxin.
 
 
 0.990
AEE52432.1
COGs: COG0715 ABC-type nitrate/sulfonate/bicarbonate transport systems periplasmic components; KEGG: hch:HCH_06708 nitrate/sulfonate/bicarbonate ABC transporter periplasmic protein; SPTR: ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic components; IMG reference gene:2504773987.
 
 
 0.974
AEE52435.1
COGs: COG1116 ABC-type nitrate/sulfonate/bicarbonate transport system ATPase component; InterPro IPR005890:IPR003593:IPR003439; KEGG: chu:CHU_1966 ABC type nitrate transporter, ATP-binding protein; PFAM: ABC transporter-like; PRIAM: Taurine-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: ABC type nitrate transporter, ATP-binding protein; TIGRFAM: Nitrate transport ATP-binding subunit C/D; IMG reference gene:2504773990; PFAM: ABC transporter; TIGRFAM: nitrate transport ATP-binding subunits C and D.
 
  
 0.973
AEE52434.1
Taurine-transporting ATPase; COGs: COG1116 ABC-type nitrate/sulfonate/bicarbonate transport system ATPase component; InterPro IPR003593:IPR003439; KEGG: chu:CHU_1967 ABC-type nitrate transporter, ATP-binding protein; PFAM: ABC transporter-like; PRIAM: Taurine-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: ABC-type nitrate transporter, ATP-binding protein; IMG reference gene:2504773989; PFAM: ABC transporter; TIGRFAM: nitrate transport ATP-binding subunits C and D.
 
  
 0.963
AEE52433.1
ABC-type transporter, integral membrane subunit; COGs: COG0600 ABC-type nitrate/sulfonate/bicarbonate transport system permease component; InterPro IPR000515; KEGG: sde:Sde_2265 2-isopropylmalate synthase; PFAM: Binding-protein-dependent transport systems inner membrane component; SPTR: ABC transporter, permease protein; IMG reference gene:2504773988; PFAM: Binding-protein-dependent transport system inner membrane component.
 
  
 0.959
AEE53153.1
NADH dehydrogenase (quinone); COGs: COG1894 NADH:ubiquinone oxidoreductase NADH-binding (51 kD) subunit; InterPro IPR011538:IPR019554:IPR019575; KEGG: pub:SAR11_0680 NAD-dependent formate dehydrogenase subunit beta; PFAM: NADH:ubiquinone oxidoreductase, 51kDa subunit; Soluble ligand binding domain; NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding; PRIAM: NADH dehydrogenase (quinone); SPTR: NAD-dependent formate dehydrogenase beta subunit; IMG reference gene:2504774726; PFAM: NADH-ubiquinone oxidoreductase-F iron-sulfur binding region; Respiratory-chain NADH dehydrogenase [...]
  
 
 0.951
AEE52099.1
Nitrite reductase (NAD(P)H), large subunit; COGs: COG1251 NAD(P)H-nitrite reductase; InterProIPR013027:IPR007419:IPR005117:IPR006067:IPR 012744; KEGG: assimilatory nitrite reductase (nad(p)h) large subunit precursor; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; BFD-like [2Fe-2S]-binding region; Nitrite/sulphite reductase, hemoprotein beta-component, ferrodoxin-like; Nitrite/sulphite reductase 4Fe-4S region; PRIAM: Nitrite reductase (NAD(P)H); SPTR: Nitrite reductase [NAD(P)H], large subunit; TIGRFAM: Nitrite reductase [NAD(P)H] large subunit, NirB; IMG reference g [...]
 
 
0.945
AEE51940.1
COGs: COG2070 Dioxygenase related to 2-nitropropane dioxygenase; InterPro IPR004136; KEGG: dfe:Dfer_1418 2-nitropropane dioxygenase NPD; PFAM: 2-nitropropane dioxygenase, NPD; SPTR: 2-nitropropane dioxygenase NPD; IMG reference gene:2504773478; PFAM: 2-nitropropane dioxygenase.
     
 0.911
AEE52700.1
4Fe-4S ferredoxin iron-sulfur binding domain-containing protein; COGs: COG0437 Fe-S-cluster-containing hydrogenase components 1; InterPro IPR006311:IPR001450; KEGG: mtt:Ftrac_3687 quinol:cytochrome c oxidoreductase iron-sulfur protein precursor; PFAM: 4Fe-4S ferredoxin, iron-sulphur binding, subgroup; SPTR: Quinol:cytochrome c oxidoreductase iron-sulfur protein; IMG reference gene:2504774265.
  
 
 0.904
Your Current Organism:
Haliscomenobacter hydrossis
NCBI taxonomy Id: 760192
Other names: H. hydrossis DSM 1100, Haliscomenobacter hydrossis DSM 1100
Server load: low (12%) [HD]