| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AEE48837.1 | AEE51463.1 | Halhy_0936 | Halhy_3611 | Dihydroorotase, multifunctional complex type; COGs: COG0044 Dihydroorotase and related cyclic amidohydrolase; InterPro IPR006680:IPR004722; KEGG: dfe:Dfer_4467 dihydroorotase, multifunctional complex type; PFAM: Amidohydrolase 1; SPTR: Dihydroorotase, multifunctional complex type; TIGRFAM: Dihydroorotase multifunctional complex type; IMG reference gene:2504770296; TIGRFAM: dihydroorotase, multifunctional complex type. | COGs: COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ); InterPro IPR006275:IPR005481:IPR005479:IPR005480; KEGG: phe:Phep_0124 carbamoyl phosphate synthase large subunit; PFAM: Carbamoyl phosphate synthetase, large subunit, ATP-binding; Carbamoyl phosphate synthase, large subunit, N-terminal; Carbamoyl phosphate synthetase, large subunit, oligomerisation; PRIAM: Carbamoyl-phosphate synthase (ammonia); SPTR: Carbamoyl-phosphate synthase, large subunit; TIGRFAM: Carbamoyl phosphate synthase, large subunit, glutamine-dependent; IMG reference gene:2504772992; PFAM: Carba [...] | 0.975 |
| AEE48837.1 | AEE53893.1 | Halhy_0936 | Halhy_6071 | Dihydroorotase, multifunctional complex type; COGs: COG0044 Dihydroorotase and related cyclic amidohydrolase; InterPro IPR006680:IPR004722; KEGG: dfe:Dfer_4467 dihydroorotase, multifunctional complex type; PFAM: Amidohydrolase 1; SPTR: Dihydroorotase, multifunctional complex type; TIGRFAM: Dihydroorotase multifunctional complex type; IMG reference gene:2504770296; TIGRFAM: dihydroorotase, multifunctional complex type. | Dihydroorotase, multifunctional complex type; COGs: COG0044 Dihydroorotase and related cyclic amidohydrolase; InterPro IPR004722:IPR006680; KEGG: sli:Slin_5385 amidohydrolase; PFAM: Amidohydrolase 1; PRIAM: Allantoinase; SPTR: Amidohydrolase; TIGRFAM: Dihydroorotase multifunctional complex type; IMG reference gene:2504775473; PFAM: Amidohydrolase family; TIGRFAM: dihydroorotase, multifunctional complex type. | 0.926 |
| AEE48837.1 | AEE54318.1 | Halhy_0936 | Halhy_6502 | Dihydroorotase, multifunctional complex type; COGs: COG0044 Dihydroorotase and related cyclic amidohydrolase; InterPro IPR006680:IPR004722; KEGG: dfe:Dfer_4467 dihydroorotase, multifunctional complex type; PFAM: Amidohydrolase 1; SPTR: Dihydroorotase, multifunctional complex type; TIGRFAM: Dihydroorotase multifunctional complex type; IMG reference gene:2504770296; TIGRFAM: dihydroorotase, multifunctional complex type. | COGs: COG0284 Orotidine-5'-phosphate decarboxylase; InterPro IPR011995:IPR001754; KEGG: pmz:HMPREF0659_A6727 orotidine 5'-phosphate decarboxylase; PFAM: Orotidine 5'-phosphate decarboxylase, core; PRIAM: Orotidine-5'-phosphate decarboxylase; SPTR: Orotidine 5'-phosphate decarboxylase; TIGRFAM: Orotidine 5'-phosphate decarboxylase, subfamily 2, core; IMG reference gene:2504775911; PFAM: Orotidine 5'-phosphate decarboxylase / HUMPS family; TIGRFAM: orotidine 5'-phosphate decarboxylase, subfamily 2. | 0.813 |
| AEE48837.1 | carA | Halhy_0936 | Halhy_4776 | Dihydroorotase, multifunctional complex type; COGs: COG0044 Dihydroorotase and related cyclic amidohydrolase; InterPro IPR006680:IPR004722; KEGG: dfe:Dfer_4467 dihydroorotase, multifunctional complex type; PFAM: Amidohydrolase 1; SPTR: Dihydroorotase, multifunctional complex type; TIGRFAM: Dihydroorotase multifunctional complex type; IMG reference gene:2504770296; TIGRFAM: dihydroorotase, multifunctional complex type. | COGs: COG0505 Carbamoylphosphate synthase small subunit; InterPro IPR006274:IPR002474:IPR000991; KEGG: phe:Phep_0705 carbamoyl phosphate synthase small subunit; PFAM: Carbamoyl phosphate synthase, small subunit, N-terminal; Glutamine amidotransferase class-I, C-terminal; PRIAM: Carbamoyl-phosphate synthase (glutamine-hydrolyzing); SPTR: Carbamoyl-phosphate synthase, small subunit; TIGRFAM: Carbamoyl phosphate synthase, small subunit; IMG reference gene:2504774168; PFAM: Carbamoyl-phosphate synthase small chain, CPSase domain; Glutamine amidotransferase class-I; TIGRFAM: carbamoyl-phosp [...] | 0.990 |
| AEE48837.1 | pyrB | Halhy_0936 | Halhy_0998 | Dihydroorotase, multifunctional complex type; COGs: COG0044 Dihydroorotase and related cyclic amidohydrolase; InterPro IPR006680:IPR004722; KEGG: dfe:Dfer_4467 dihydroorotase, multifunctional complex type; PFAM: Amidohydrolase 1; SPTR: Dihydroorotase, multifunctional complex type; TIGRFAM: Dihydroorotase multifunctional complex type; IMG reference gene:2504770296; TIGRFAM: dihydroorotase, multifunctional complex type. | COGs: COG0540 Aspartate carbamoyltransferase catalytic chain; HAMAP: Aspartate carbamoyltransferase; InterPro IPR006132:IPR006131:IPR002082; KEGG: chu:CHU_0084 aspartate carbamoyltransferase catalytic subunit; PFAM: Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding; Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding region; PRIAM: Aspartate carbamoyltransferase; SPTR: Aspartate carbamoyltransferase; TIGRFAM: Aspartate carbamoyltransferase, eukaryotic; IMG reference gene:2504770358; PFAM: Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Aspartate/ [...] | 0.999 |
| AEE48837.1 | pyrD | Halhy_0936 | Halhy_3413 | Dihydroorotase, multifunctional complex type; COGs: COG0044 Dihydroorotase and related cyclic amidohydrolase; InterPro IPR006680:IPR004722; KEGG: dfe:Dfer_4467 dihydroorotase, multifunctional complex type; PFAM: Amidohydrolase 1; SPTR: Dihydroorotase, multifunctional complex type; TIGRFAM: Dihydroorotase multifunctional complex type; IMG reference gene:2504770296; TIGRFAM: dihydroorotase, multifunctional complex type. | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | 0.984 |
| AEE48837.1 | pyrE | Halhy_0936 | Halhy_6291 | Dihydroorotase, multifunctional complex type; COGs: COG0044 Dihydroorotase and related cyclic amidohydrolase; InterPro IPR006680:IPR004722; KEGG: dfe:Dfer_4467 dihydroorotase, multifunctional complex type; PFAM: Amidohydrolase 1; SPTR: Dihydroorotase, multifunctional complex type; TIGRFAM: Dihydroorotase multifunctional complex type; IMG reference gene:2504770296; TIGRFAM: dihydroorotase, multifunctional complex type. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.859 |
| AEE50531.1 | AEE51463.1 | Halhy_2662 | Halhy_3611 | Amidophosphoribosyltransferase; COGs: COG0034 Glutamine phosphoribosylpyrophosphate amidotransferase; InterPro IPR000583; KEGG: rbi:RB2501_07515 amidophosphoribosyltransferase; PFAM: Glutamine amidotransferase, class-II; PRIAM: Amidophosphoribosyltransferase; SPTR: Amidophosphoribosyltransferase; IMG reference gene:2504772033; PFAM: Glutamine amidotransferases class-II. | COGs: COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ); InterPro IPR006275:IPR005481:IPR005479:IPR005480; KEGG: phe:Phep_0124 carbamoyl phosphate synthase large subunit; PFAM: Carbamoyl phosphate synthetase, large subunit, ATP-binding; Carbamoyl phosphate synthase, large subunit, N-terminal; Carbamoyl phosphate synthetase, large subunit, oligomerisation; PRIAM: Carbamoyl-phosphate synthase (ammonia); SPTR: Carbamoyl-phosphate synthase, large subunit; TIGRFAM: Carbamoyl phosphate synthase, large subunit, glutamine-dependent; IMG reference gene:2504772992; PFAM: Carba [...] | 0.983 |
| AEE50531.1 | AEE53893.1 | Halhy_2662 | Halhy_6071 | Amidophosphoribosyltransferase; COGs: COG0034 Glutamine phosphoribosylpyrophosphate amidotransferase; InterPro IPR000583; KEGG: rbi:RB2501_07515 amidophosphoribosyltransferase; PFAM: Glutamine amidotransferase, class-II; PRIAM: Amidophosphoribosyltransferase; SPTR: Amidophosphoribosyltransferase; IMG reference gene:2504772033; PFAM: Glutamine amidotransferases class-II. | Dihydroorotase, multifunctional complex type; COGs: COG0044 Dihydroorotase and related cyclic amidohydrolase; InterPro IPR004722:IPR006680; KEGG: sli:Slin_5385 amidohydrolase; PFAM: Amidohydrolase 1; PRIAM: Allantoinase; SPTR: Amidohydrolase; TIGRFAM: Dihydroorotase multifunctional complex type; IMG reference gene:2504775473; PFAM: Amidohydrolase family; TIGRFAM: dihydroorotase, multifunctional complex type. | 0.412 |
| AEE50531.1 | AEE54318.1 | Halhy_2662 | Halhy_6502 | Amidophosphoribosyltransferase; COGs: COG0034 Glutamine phosphoribosylpyrophosphate amidotransferase; InterPro IPR000583; KEGG: rbi:RB2501_07515 amidophosphoribosyltransferase; PFAM: Glutamine amidotransferase, class-II; PRIAM: Amidophosphoribosyltransferase; SPTR: Amidophosphoribosyltransferase; IMG reference gene:2504772033; PFAM: Glutamine amidotransferases class-II. | COGs: COG0284 Orotidine-5'-phosphate decarboxylase; InterPro IPR011995:IPR001754; KEGG: pmz:HMPREF0659_A6727 orotidine 5'-phosphate decarboxylase; PFAM: Orotidine 5'-phosphate decarboxylase, core; PRIAM: Orotidine-5'-phosphate decarboxylase; SPTR: Orotidine 5'-phosphate decarboxylase; TIGRFAM: Orotidine 5'-phosphate decarboxylase, subfamily 2, core; IMG reference gene:2504775911; PFAM: Orotidine 5'-phosphate decarboxylase / HUMPS family; TIGRFAM: orotidine 5'-phosphate decarboxylase, subfamily 2. | 0.722 |
| AEE50531.1 | carA | Halhy_2662 | Halhy_4776 | Amidophosphoribosyltransferase; COGs: COG0034 Glutamine phosphoribosylpyrophosphate amidotransferase; InterPro IPR000583; KEGG: rbi:RB2501_07515 amidophosphoribosyltransferase; PFAM: Glutamine amidotransferase, class-II; PRIAM: Amidophosphoribosyltransferase; SPTR: Amidophosphoribosyltransferase; IMG reference gene:2504772033; PFAM: Glutamine amidotransferases class-II. | COGs: COG0505 Carbamoylphosphate synthase small subunit; InterPro IPR006274:IPR002474:IPR000991; KEGG: phe:Phep_0705 carbamoyl phosphate synthase small subunit; PFAM: Carbamoyl phosphate synthase, small subunit, N-terminal; Glutamine amidotransferase class-I, C-terminal; PRIAM: Carbamoyl-phosphate synthase (glutamine-hydrolyzing); SPTR: Carbamoyl-phosphate synthase, small subunit; TIGRFAM: Carbamoyl phosphate synthase, small subunit; IMG reference gene:2504774168; PFAM: Carbamoyl-phosphate synthase small chain, CPSase domain; Glutamine amidotransferase class-I; TIGRFAM: carbamoyl-phosp [...] | 0.978 |
| AEE50531.1 | glmS | Halhy_2662 | Halhy_2631 | Amidophosphoribosyltransferase; COGs: COG0034 Glutamine phosphoribosylpyrophosphate amidotransferase; InterPro IPR000583; KEGG: rbi:RB2501_07515 amidophosphoribosyltransferase; PFAM: Glutamine amidotransferase, class-II; PRIAM: Amidophosphoribosyltransferase; SPTR: Amidophosphoribosyltransferase; IMG reference gene:2504772033; PFAM: Glutamine amidotransferases class-II. | Glucosamine--fructose-6-phosphate aminotransferase (isomerizing); Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | 0.927 |
| AEE50531.1 | purQ | Halhy_2662 | Halhy_4319 | Amidophosphoribosyltransferase; COGs: COG0034 Glutamine phosphoribosylpyrophosphate amidotransferase; InterPro IPR000583; KEGG: rbi:RB2501_07515 amidophosphoribosyltransferase; PFAM: Glutamine amidotransferase, class-II; PRIAM: Amidophosphoribosyltransferase; SPTR: Amidophosphoribosyltransferase; IMG reference gene:2504772033; PFAM: Glutamine amidotransferases class-II. | Phosphoribosylformylglycinamidine synthase 1; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] | 0.993 |
| AEE50531.1 | pyrB | Halhy_2662 | Halhy_0998 | Amidophosphoribosyltransferase; COGs: COG0034 Glutamine phosphoribosylpyrophosphate amidotransferase; InterPro IPR000583; KEGG: rbi:RB2501_07515 amidophosphoribosyltransferase; PFAM: Glutamine amidotransferase, class-II; PRIAM: Amidophosphoribosyltransferase; SPTR: Amidophosphoribosyltransferase; IMG reference gene:2504772033; PFAM: Glutamine amidotransferases class-II. | COGs: COG0540 Aspartate carbamoyltransferase catalytic chain; HAMAP: Aspartate carbamoyltransferase; InterPro IPR006132:IPR006131:IPR002082; KEGG: chu:CHU_0084 aspartate carbamoyltransferase catalytic subunit; PFAM: Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding; Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding region; PRIAM: Aspartate carbamoyltransferase; SPTR: Aspartate carbamoyltransferase; TIGRFAM: Aspartate carbamoyltransferase, eukaryotic; IMG reference gene:2504770358; PFAM: Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Aspartate/ [...] | 0.615 |
| AEE50531.1 | pyrD | Halhy_2662 | Halhy_3413 | Amidophosphoribosyltransferase; COGs: COG0034 Glutamine phosphoribosylpyrophosphate amidotransferase; InterPro IPR000583; KEGG: rbi:RB2501_07515 amidophosphoribosyltransferase; PFAM: Glutamine amidotransferase, class-II; PRIAM: Amidophosphoribosyltransferase; SPTR: Amidophosphoribosyltransferase; IMG reference gene:2504772033; PFAM: Glutamine amidotransferases class-II. | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | 0.550 |
| AEE50531.1 | pyrE | Halhy_2662 | Halhy_6291 | Amidophosphoribosyltransferase; COGs: COG0034 Glutamine phosphoribosylpyrophosphate amidotransferase; InterPro IPR000583; KEGG: rbi:RB2501_07515 amidophosphoribosyltransferase; PFAM: Glutamine amidotransferase, class-II; PRIAM: Amidophosphoribosyltransferase; SPTR: Amidophosphoribosyltransferase; IMG reference gene:2504772033; PFAM: Glutamine amidotransferases class-II. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.606 |
| AEE51463.1 | AEE48837.1 | Halhy_3611 | Halhy_0936 | COGs: COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ); InterPro IPR006275:IPR005481:IPR005479:IPR005480; KEGG: phe:Phep_0124 carbamoyl phosphate synthase large subunit; PFAM: Carbamoyl phosphate synthetase, large subunit, ATP-binding; Carbamoyl phosphate synthase, large subunit, N-terminal; Carbamoyl phosphate synthetase, large subunit, oligomerisation; PRIAM: Carbamoyl-phosphate synthase (ammonia); SPTR: Carbamoyl-phosphate synthase, large subunit; TIGRFAM: Carbamoyl phosphate synthase, large subunit, glutamine-dependent; IMG reference gene:2504772992; PFAM: Carba [...] | Dihydroorotase, multifunctional complex type; COGs: COG0044 Dihydroorotase and related cyclic amidohydrolase; InterPro IPR006680:IPR004722; KEGG: dfe:Dfer_4467 dihydroorotase, multifunctional complex type; PFAM: Amidohydrolase 1; SPTR: Dihydroorotase, multifunctional complex type; TIGRFAM: Dihydroorotase multifunctional complex type; IMG reference gene:2504770296; TIGRFAM: dihydroorotase, multifunctional complex type. | 0.975 |
| AEE51463.1 | AEE50531.1 | Halhy_3611 | Halhy_2662 | COGs: COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ); InterPro IPR006275:IPR005481:IPR005479:IPR005480; KEGG: phe:Phep_0124 carbamoyl phosphate synthase large subunit; PFAM: Carbamoyl phosphate synthetase, large subunit, ATP-binding; Carbamoyl phosphate synthase, large subunit, N-terminal; Carbamoyl phosphate synthetase, large subunit, oligomerisation; PRIAM: Carbamoyl-phosphate synthase (ammonia); SPTR: Carbamoyl-phosphate synthase, large subunit; TIGRFAM: Carbamoyl phosphate synthase, large subunit, glutamine-dependent; IMG reference gene:2504772992; PFAM: Carba [...] | Amidophosphoribosyltransferase; COGs: COG0034 Glutamine phosphoribosylpyrophosphate amidotransferase; InterPro IPR000583; KEGG: rbi:RB2501_07515 amidophosphoribosyltransferase; PFAM: Glutamine amidotransferase, class-II; PRIAM: Amidophosphoribosyltransferase; SPTR: Amidophosphoribosyltransferase; IMG reference gene:2504772033; PFAM: Glutamine amidotransferases class-II. | 0.983 |
| AEE51463.1 | AEE53893.1 | Halhy_3611 | Halhy_6071 | COGs: COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ); InterPro IPR006275:IPR005481:IPR005479:IPR005480; KEGG: phe:Phep_0124 carbamoyl phosphate synthase large subunit; PFAM: Carbamoyl phosphate synthetase, large subunit, ATP-binding; Carbamoyl phosphate synthase, large subunit, N-terminal; Carbamoyl phosphate synthetase, large subunit, oligomerisation; PRIAM: Carbamoyl-phosphate synthase (ammonia); SPTR: Carbamoyl-phosphate synthase, large subunit; TIGRFAM: Carbamoyl phosphate synthase, large subunit, glutamine-dependent; IMG reference gene:2504772992; PFAM: Carba [...] | Dihydroorotase, multifunctional complex type; COGs: COG0044 Dihydroorotase and related cyclic amidohydrolase; InterPro IPR004722:IPR006680; KEGG: sli:Slin_5385 amidohydrolase; PFAM: Amidohydrolase 1; PRIAM: Allantoinase; SPTR: Amidohydrolase; TIGRFAM: Dihydroorotase multifunctional complex type; IMG reference gene:2504775473; PFAM: Amidohydrolase family; TIGRFAM: dihydroorotase, multifunctional complex type. | 0.986 |
| AEE51463.1 | AEE54318.1 | Halhy_3611 | Halhy_6502 | COGs: COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ); InterPro IPR006275:IPR005481:IPR005479:IPR005480; KEGG: phe:Phep_0124 carbamoyl phosphate synthase large subunit; PFAM: Carbamoyl phosphate synthetase, large subunit, ATP-binding; Carbamoyl phosphate synthase, large subunit, N-terminal; Carbamoyl phosphate synthetase, large subunit, oligomerisation; PRIAM: Carbamoyl-phosphate synthase (ammonia); SPTR: Carbamoyl-phosphate synthase, large subunit; TIGRFAM: Carbamoyl phosphate synthase, large subunit, glutamine-dependent; IMG reference gene:2504772992; PFAM: Carba [...] | COGs: COG0284 Orotidine-5'-phosphate decarboxylase; InterPro IPR011995:IPR001754; KEGG: pmz:HMPREF0659_A6727 orotidine 5'-phosphate decarboxylase; PFAM: Orotidine 5'-phosphate decarboxylase, core; PRIAM: Orotidine-5'-phosphate decarboxylase; SPTR: Orotidine 5'-phosphate decarboxylase; TIGRFAM: Orotidine 5'-phosphate decarboxylase, subfamily 2, core; IMG reference gene:2504775911; PFAM: Orotidine 5'-phosphate decarboxylase / HUMPS family; TIGRFAM: orotidine 5'-phosphate decarboxylase, subfamily 2. | 0.946 |