Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
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Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEE52614.1Major facilitator superfamily MFS_1; COGs: COG2814 Arabinose efflux permease; InterPro IPR011701; KEGG: sli:Slin_4881 major facilitator superfamily MFS_1; PFAM: Major facilitator superfamily MFS-1; SPTR: Major facilitator superfamily MFS_1; IMG reference gene:2504774172; PFAM: Major Facilitator Superfamily; TIGRFAM: Multidrug resistance protein. (405 aa)    
Predicted Functional Partners:
hemH
Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family.
 
      0.637
sucD
succinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
       0.499
AEE52615.1
COGs: COG0463 Glycosyltransferase involved in cell wall biogenesis; InterPro IPR001173; KEGG: lpa:lpa_03609 glycosyltransferase, group 2 family protein; PFAM: Glycosyl transferase, family 2; SPTR: Glycosyl transferase family 2; IMG reference gene:2504774173; PFAM: Glycosyl transferase family 2.
       0.440
AEE54077.1
KEGG: rde:RD1_3981 cupin domain-containing protein; SPTR: Cupin domain protein; IMG reference gene:2504775664; PFAM: Cupin domain.
  
     0.408
Your Current Organism:
Haliscomenobacter hydrossis
NCBI taxonomy Id: 760192
Other names: H. hydrossis DSM 1100, Haliscomenobacter hydrossis DSM 1100
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