| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AEE49729.1 | AEE52662.1 | Halhy_1844 | Halhy_4829 | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | COGs: COG0294 Dihydropteroate synthase; InterPro IPR006390:IPR000489; KEGG: cpi:Cpin_5465 dihydropteroate synthase; PFAM: Dihydropteroate synthase, DHPS; PRIAM: Dihydropteroate synthase; SPTR: Dihydropteroate synthase; TIGRFAM: Dihydropteroate synthase; IMG reference gene:2504774223; PFAM: Pterin binding enzyme; TIGRFAM: dihydropteroate synthase. | 0.993 |
| AEE49729.1 | AEE52951.1 | Halhy_1844 | Halhy_5125 | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | COGs: COG0801 7 8-dihydro-6-hydroxymethylpterin-pyrophosphokinase; InterPro IPR000550; KEGG: dfe:Dfer_3568 2-amino-4-hydroxy-6-hydroxymethyldihydropteridin epyrophosphokinase; PFAM: 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK; PRIAM:2-amino-4-hydroxy-6-hydroxymethyldihydropteri dinediphosphokinase; SPTR:2-amino-4-hydroxy-6-hydroxymethyldihydropterid inepyrophosphokinase; TIGRFAM: 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK; IMG reference gene:2504774523; PFAM: 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK); TIGRFAM: 2-amino-4-hydroxy-6-hydroxymet [...] | 0.994 |
| AEE49729.1 | AEE53195.1 | Halhy_1844 | Halhy_5370 | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | FolC bifunctional protein; COGs: COG0285 Folylpolyglutamate synthase; InterPro IPR001645:IPR013221; KEGG: phe:Phep_1166 FolC bifunctional protein; PFAM: Mur ligase, central; PRIAM: Tetrahydrofolate synthase; SPTR: FolC bifunctional protein; TIGRFAM: Folylpolyglutamate synthetase; IMG reference gene:2504774768; PFAM: Mur ligase middle domain; TIGRFAM: folylpolyglutamate synthase/dihydrofolate synthase. | 0.602 |
| AEE49729.1 | folE | Halhy_1844 | Halhy_0838 | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | COGs: COG0302 GTP cyclohydrolase I; HAMAP: GTP cyclohydrolase I; InterPro IPR001474:IPR020602; KEGG: cts:Ctha_0487 GTP cyclohydrolase I; PFAM: GTP cyclohydrolase I/Nitrile oxidoreductase; PRIAM: GTP cyclohydrolase I; SPTR: GTP cyclohydrolase 1 2; TIGRFAM: GTP cyclohydrolase I; IMG reference gene:2504770198; PFAM: GTP cyclohydrolase I; TIGRFAM: GTP cyclohydrolase I. | 0.951 |
| AEE51669.1 | AEE52662.1 | Halhy_3817 | Halhy_4829 | Hypothetical protein; COGs: COG1237 Metal-dependent hydrolase of the beta-lactamase superfamily II; KEGG: bja:bll2990 hypothetical protein; SPTR: Bll2990 protein; IMG reference gene:2504773201; PFAM: Metallo-beta-lactamase superfamily. | COGs: COG0294 Dihydropteroate synthase; InterPro IPR006390:IPR000489; KEGG: cpi:Cpin_5465 dihydropteroate synthase; PFAM: Dihydropteroate synthase, DHPS; PRIAM: Dihydropteroate synthase; SPTR: Dihydropteroate synthase; TIGRFAM: Dihydropteroate synthase; IMG reference gene:2504774223; PFAM: Pterin binding enzyme; TIGRFAM: dihydropteroate synthase. | 0.900 |
| AEE51669.1 | AEE52951.1 | Halhy_3817 | Halhy_5125 | Hypothetical protein; COGs: COG1237 Metal-dependent hydrolase of the beta-lactamase superfamily II; KEGG: bja:bll2990 hypothetical protein; SPTR: Bll2990 protein; IMG reference gene:2504773201; PFAM: Metallo-beta-lactamase superfamily. | COGs: COG0801 7 8-dihydro-6-hydroxymethylpterin-pyrophosphokinase; InterPro IPR000550; KEGG: dfe:Dfer_3568 2-amino-4-hydroxy-6-hydroxymethyldihydropteridin epyrophosphokinase; PFAM: 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK; PRIAM:2-amino-4-hydroxy-6-hydroxymethyldihydropteri dinediphosphokinase; SPTR:2-amino-4-hydroxy-6-hydroxymethyldihydropterid inepyrophosphokinase; TIGRFAM: 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK; IMG reference gene:2504774523; PFAM: 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK); TIGRFAM: 2-amino-4-hydroxy-6-hydroxymet [...] | 0.900 |
| AEE52662.1 | AEE49729.1 | Halhy_4829 | Halhy_1844 | COGs: COG0294 Dihydropteroate synthase; InterPro IPR006390:IPR000489; KEGG: cpi:Cpin_5465 dihydropteroate synthase; PFAM: Dihydropteroate synthase, DHPS; PRIAM: Dihydropteroate synthase; SPTR: Dihydropteroate synthase; TIGRFAM: Dihydropteroate synthase; IMG reference gene:2504774223; PFAM: Pterin binding enzyme; TIGRFAM: dihydropteroate synthase. | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 0.993 |
| AEE52662.1 | AEE51669.1 | Halhy_4829 | Halhy_3817 | COGs: COG0294 Dihydropteroate synthase; InterPro IPR006390:IPR000489; KEGG: cpi:Cpin_5465 dihydropteroate synthase; PFAM: Dihydropteroate synthase, DHPS; PRIAM: Dihydropteroate synthase; SPTR: Dihydropteroate synthase; TIGRFAM: Dihydropteroate synthase; IMG reference gene:2504774223; PFAM: Pterin binding enzyme; TIGRFAM: dihydropteroate synthase. | Hypothetical protein; COGs: COG1237 Metal-dependent hydrolase of the beta-lactamase superfamily II; KEGG: bja:bll2990 hypothetical protein; SPTR: Bll2990 protein; IMG reference gene:2504773201; PFAM: Metallo-beta-lactamase superfamily. | 0.900 |
| AEE52662.1 | AEE52663.1 | Halhy_4829 | Halhy_4830 | COGs: COG0294 Dihydropteroate synthase; InterPro IPR006390:IPR000489; KEGG: cpi:Cpin_5465 dihydropteroate synthase; PFAM: Dihydropteroate synthase, DHPS; PRIAM: Dihydropteroate synthase; SPTR: Dihydropteroate synthase; TIGRFAM: Dihydropteroate synthase; IMG reference gene:2504774223; PFAM: Pterin binding enzyme; TIGRFAM: dihydropteroate synthase. | Hypothetical protein; IMG reference gene:2504774224. | 0.773 |
| AEE52662.1 | AEE52664.1 | Halhy_4829 | Halhy_4831 | COGs: COG0294 Dihydropteroate synthase; InterPro IPR006390:IPR000489; KEGG: cpi:Cpin_5465 dihydropteroate synthase; PFAM: Dihydropteroate synthase, DHPS; PRIAM: Dihydropteroate synthase; SPTR: Dihydropteroate synthase; TIGRFAM: Dihydropteroate synthase; IMG reference gene:2504774223; PFAM: Pterin binding enzyme; TIGRFAM: dihydropteroate synthase. | Cell surface receptor IPT/TIG domain protein; InterPro IPR013519:IPR002909:IPR013517; KEGG: chu:CHU_3220 hypothetical protein; PFAM: Cell surface receptor IPT/TIG; FG-GAP; SMART: Integrin alpha beta-propellor; SPTR: CHU large protein; candidate retaining b-glycosidase, glycoside hydrolase family 5 protein; IMG reference gene:2504774225; PFAM: IPT/TIG domain; FG-GAP repeat. | 0.651 |
| AEE52662.1 | AEE52822.1 | Halhy_4829 | Halhy_4994 | COGs: COG0294 Dihydropteroate synthase; InterPro IPR006390:IPR000489; KEGG: cpi:Cpin_5465 dihydropteroate synthase; PFAM: Dihydropteroate synthase, DHPS; PRIAM: Dihydropteroate synthase; SPTR: Dihydropteroate synthase; TIGRFAM: Dihydropteroate synthase; IMG reference gene:2504774223; PFAM: Pterin binding enzyme; TIGRFAM: dihydropteroate synthase. | Glutamine amidotransferase of anthranilate synthase; COGs: COG0512 Anthranilate/para-aminobenzoate synthase component II; InterPro IPR000991:IPR006221; KEGG: fba:FIC_01496 anthranilate synthase, amidotransferase component; PFAM: Glutamine amidotransferase class-I, C-terminal; PRIAM: Anthranilate synthase; SPTR: Anthranilate synthase, amidotransferase component; TIGRFAM: Glutamine amidotransferase of anthranilate synthase; IMG reference gene:2504774389; PFAM: Glutamine amidotransferase class-I; TIGRFAM: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase. | 0.629 |
| AEE52662.1 | AEE52951.1 | Halhy_4829 | Halhy_5125 | COGs: COG0294 Dihydropteroate synthase; InterPro IPR006390:IPR000489; KEGG: cpi:Cpin_5465 dihydropteroate synthase; PFAM: Dihydropteroate synthase, DHPS; PRIAM: Dihydropteroate synthase; SPTR: Dihydropteroate synthase; TIGRFAM: Dihydropteroate synthase; IMG reference gene:2504774223; PFAM: Pterin binding enzyme; TIGRFAM: dihydropteroate synthase. | COGs: COG0801 7 8-dihydro-6-hydroxymethylpterin-pyrophosphokinase; InterPro IPR000550; KEGG: dfe:Dfer_3568 2-amino-4-hydroxy-6-hydroxymethyldihydropteridin epyrophosphokinase; PFAM: 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK; PRIAM:2-amino-4-hydroxy-6-hydroxymethyldihydropteri dinediphosphokinase; SPTR:2-amino-4-hydroxy-6-hydroxymethyldihydropterid inepyrophosphokinase; TIGRFAM: 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK; IMG reference gene:2504774523; PFAM: 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK); TIGRFAM: 2-amino-4-hydroxy-6-hydroxymet [...] | 0.999 |
| AEE52662.1 | AEE53195.1 | Halhy_4829 | Halhy_5370 | COGs: COG0294 Dihydropteroate synthase; InterPro IPR006390:IPR000489; KEGG: cpi:Cpin_5465 dihydropteroate synthase; PFAM: Dihydropteroate synthase, DHPS; PRIAM: Dihydropteroate synthase; SPTR: Dihydropteroate synthase; TIGRFAM: Dihydropteroate synthase; IMG reference gene:2504774223; PFAM: Pterin binding enzyme; TIGRFAM: dihydropteroate synthase. | FolC bifunctional protein; COGs: COG0285 Folylpolyglutamate synthase; InterPro IPR001645:IPR013221; KEGG: phe:Phep_1166 FolC bifunctional protein; PFAM: Mur ligase, central; PRIAM: Tetrahydrofolate synthase; SPTR: FolC bifunctional protein; TIGRFAM: Folylpolyglutamate synthetase; IMG reference gene:2504774768; PFAM: Mur ligase middle domain; TIGRFAM: folylpolyglutamate synthase/dihydrofolate synthase. | 0.997 |
| AEE52662.1 | folE | Halhy_4829 | Halhy_0838 | COGs: COG0294 Dihydropteroate synthase; InterPro IPR006390:IPR000489; KEGG: cpi:Cpin_5465 dihydropteroate synthase; PFAM: Dihydropteroate synthase, DHPS; PRIAM: Dihydropteroate synthase; SPTR: Dihydropteroate synthase; TIGRFAM: Dihydropteroate synthase; IMG reference gene:2504774223; PFAM: Pterin binding enzyme; TIGRFAM: dihydropteroate synthase. | COGs: COG0302 GTP cyclohydrolase I; HAMAP: GTP cyclohydrolase I; InterPro IPR001474:IPR020602; KEGG: cts:Ctha_0487 GTP cyclohydrolase I; PFAM: GTP cyclohydrolase I/Nitrile oxidoreductase; PRIAM: GTP cyclohydrolase I; SPTR: GTP cyclohydrolase 1 2; TIGRFAM: GTP cyclohydrolase I; IMG reference gene:2504770198; PFAM: GTP cyclohydrolase I; TIGRFAM: GTP cyclohydrolase I. | 0.969 |
| AEE52662.1 | guaB | Halhy_4829 | Halhy_1322 | COGs: COG0294 Dihydropteroate synthase; InterPro IPR006390:IPR000489; KEGG: cpi:Cpin_5465 dihydropteroate synthase; PFAM: Dihydropteroate synthase, DHPS; PRIAM: Dihydropteroate synthase; SPTR: Dihydropteroate synthase; TIGRFAM: Dihydropteroate synthase; IMG reference gene:2504774223; PFAM: Pterin binding enzyme; TIGRFAM: dihydropteroate synthase. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.644 |
| AEE52662.1 | ribH | Halhy_4829 | Halhy_5566 | COGs: COG0294 Dihydropteroate synthase; InterPro IPR006390:IPR000489; KEGG: cpi:Cpin_5465 dihydropteroate synthase; PFAM: Dihydropteroate synthase, DHPS; PRIAM: Dihydropteroate synthase; SPTR: Dihydropteroate synthase; TIGRFAM: Dihydropteroate synthase; IMG reference gene:2504774223; PFAM: Pterin binding enzyme; TIGRFAM: dihydropteroate synthase. | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. | 0.641 |
| AEE52663.1 | AEE52662.1 | Halhy_4830 | Halhy_4829 | Hypothetical protein; IMG reference gene:2504774224. | COGs: COG0294 Dihydropteroate synthase; InterPro IPR006390:IPR000489; KEGG: cpi:Cpin_5465 dihydropteroate synthase; PFAM: Dihydropteroate synthase, DHPS; PRIAM: Dihydropteroate synthase; SPTR: Dihydropteroate synthase; TIGRFAM: Dihydropteroate synthase; IMG reference gene:2504774223; PFAM: Pterin binding enzyme; TIGRFAM: dihydropteroate synthase. | 0.773 |
| AEE52663.1 | AEE52664.1 | Halhy_4830 | Halhy_4831 | Hypothetical protein; IMG reference gene:2504774224. | Cell surface receptor IPT/TIG domain protein; InterPro IPR013519:IPR002909:IPR013517; KEGG: chu:CHU_3220 hypothetical protein; PFAM: Cell surface receptor IPT/TIG; FG-GAP; SMART: Integrin alpha beta-propellor; SPTR: CHU large protein; candidate retaining b-glycosidase, glycoside hydrolase family 5 protein; IMG reference gene:2504774225; PFAM: IPT/TIG domain; FG-GAP repeat. | 0.651 |
| AEE52664.1 | AEE52662.1 | Halhy_4831 | Halhy_4829 | Cell surface receptor IPT/TIG domain protein; InterPro IPR013519:IPR002909:IPR013517; KEGG: chu:CHU_3220 hypothetical protein; PFAM: Cell surface receptor IPT/TIG; FG-GAP; SMART: Integrin alpha beta-propellor; SPTR: CHU large protein; candidate retaining b-glycosidase, glycoside hydrolase family 5 protein; IMG reference gene:2504774225; PFAM: IPT/TIG domain; FG-GAP repeat. | COGs: COG0294 Dihydropteroate synthase; InterPro IPR006390:IPR000489; KEGG: cpi:Cpin_5465 dihydropteroate synthase; PFAM: Dihydropteroate synthase, DHPS; PRIAM: Dihydropteroate synthase; SPTR: Dihydropteroate synthase; TIGRFAM: Dihydropteroate synthase; IMG reference gene:2504774223; PFAM: Pterin binding enzyme; TIGRFAM: dihydropteroate synthase. | 0.651 |
| AEE52664.1 | AEE52663.1 | Halhy_4831 | Halhy_4830 | Cell surface receptor IPT/TIG domain protein; InterPro IPR013519:IPR002909:IPR013517; KEGG: chu:CHU_3220 hypothetical protein; PFAM: Cell surface receptor IPT/TIG; FG-GAP; SMART: Integrin alpha beta-propellor; SPTR: CHU large protein; candidate retaining b-glycosidase, glycoside hydrolase family 5 protein; IMG reference gene:2504774225; PFAM: IPT/TIG domain; FG-GAP repeat. | Hypothetical protein; IMG reference gene:2504774224. | 0.651 |
