| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AEE52665.1 | AEE52666.1 | Halhy_4832 | Halhy_4833 | Hydrolase, TatD family; COGs: COG0084 Mg-dependent DNase; InterPro IPR015991:IPR001130; KEGG: cpi:Cpin_0246 hydrolase, TatD family; PFAM: Deoxyribonuclease, TatD-related; SPTR: Hydrolase, TatD family; TIGRFAM: Deoxyribonuclease, TatD Mg-dependent, prokaryote; IMG reference gene:2504774227; PFAM: TatD related DNase; TIGRFAM: hydrolase, TatD family. | Ribonuclease H-related protein; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase H family. | 0.536 |
| AEE52665.1 | gltX | Halhy_4832 | Halhy_2744 | Hydrolase, TatD family; COGs: COG0084 Mg-dependent DNase; InterPro IPR015991:IPR001130; KEGG: cpi:Cpin_0246 hydrolase, TatD family; PFAM: Deoxyribonuclease, TatD-related; SPTR: Hydrolase, TatD family; TIGRFAM: Deoxyribonuclease, TatD Mg-dependent, prokaryote; IMG reference gene:2504774227; PFAM: TatD related DNase; TIGRFAM: hydrolase, TatD family. | glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. | 0.456 |
| AEE52665.1 | lepA | Halhy_4832 | Halhy_1598 | Hydrolase, TatD family; COGs: COG0084 Mg-dependent DNase; InterPro IPR015991:IPR001130; KEGG: cpi:Cpin_0246 hydrolase, TatD family; PFAM: Deoxyribonuclease, TatD-related; SPTR: Hydrolase, TatD family; TIGRFAM: Deoxyribonuclease, TatD Mg-dependent, prokaryote; IMG reference gene:2504774227; PFAM: TatD related DNase; TIGRFAM: hydrolase, TatD family. | GTP-binding protein lepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | 0.416 |
| AEE52665.1 | metG | Halhy_4832 | Halhy_2408 | Hydrolase, TatD family; COGs: COG0084 Mg-dependent DNase; InterPro IPR015991:IPR001130; KEGG: cpi:Cpin_0246 hydrolase, TatD family; PFAM: Deoxyribonuclease, TatD-related; SPTR: Hydrolase, TatD family; TIGRFAM: Deoxyribonuclease, TatD Mg-dependent, prokaryote; IMG reference gene:2504774227; PFAM: TatD related DNase; TIGRFAM: hydrolase, TatD family. | Methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | 0.541 |
| AEE52665.1 | nusA | Halhy_4832 | Halhy_3328 | Hydrolase, TatD family; COGs: COG0084 Mg-dependent DNase; InterPro IPR015991:IPR001130; KEGG: cpi:Cpin_0246 hydrolase, TatD family; PFAM: Deoxyribonuclease, TatD-related; SPTR: Hydrolase, TatD family; TIGRFAM: Deoxyribonuclease, TatD Mg-dependent, prokaryote; IMG reference gene:2504774227; PFAM: TatD related DNase; TIGRFAM: hydrolase, TatD family. | NusA antitermination factor; Participates in both transcription termination and antitermination. | 0.424 |
| AEE52665.1 | rpsI | Halhy_4832 | Halhy_2729 | Hydrolase, TatD family; COGs: COG0084 Mg-dependent DNase; InterPro IPR015991:IPR001130; KEGG: cpi:Cpin_0246 hydrolase, TatD family; PFAM: Deoxyribonuclease, TatD-related; SPTR: Hydrolase, TatD family; TIGRFAM: Deoxyribonuclease, TatD Mg-dependent, prokaryote; IMG reference gene:2504774227; PFAM: TatD related DNase; TIGRFAM: hydrolase, TatD family. | COGs: COG0103 Ribosomal protein S9; InterPro IPR000754; KEGG: dfe:Dfer_3496 30S ribosomal protein S9; PFAM: Ribosomal protein S9; SPTR: 30S ribosomal protein S9; IMG reference gene:2504772100; PFAM: Ribosomal protein S9/S16; Belongs to the universal ribosomal protein uS9 family. | 0.436 |
| AEE52665.1 | secF | Halhy_4832 | Halhy_6212 | Hydrolase, TatD family; COGs: COG0084 Mg-dependent DNase; InterPro IPR015991:IPR001130; KEGG: cpi:Cpin_0246 hydrolase, TatD family; PFAM: Deoxyribonuclease, TatD-related; SPTR: Hydrolase, TatD family; TIGRFAM: Deoxyribonuclease, TatD Mg-dependent, prokaryote; IMG reference gene:2504774227; PFAM: TatD related DNase; TIGRFAM: hydrolase, TatD family. | Protein-export membrane protein SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA; Belongs to the SecD/SecF family. SecD subfamily. | 0.572 |
| AEE52665.1 | tsaD | Halhy_4832 | Halhy_0984 | Hydrolase, TatD family; COGs: COG0084 Mg-dependent DNase; InterPro IPR015991:IPR001130; KEGG: cpi:Cpin_0246 hydrolase, TatD family; PFAM: Deoxyribonuclease, TatD-related; SPTR: Hydrolase, TatD family; TIGRFAM: Deoxyribonuclease, TatD Mg-dependent, prokaryote; IMG reference gene:2504774227; PFAM: TatD related DNase; TIGRFAM: hydrolase, TatD family. | O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | 0.510 |
| AEE52665.1 | valS | Halhy_4832 | Halhy_0087 | Hydrolase, TatD family; COGs: COG0084 Mg-dependent DNase; InterPro IPR015991:IPR001130; KEGG: cpi:Cpin_0246 hydrolase, TatD family; PFAM: Deoxyribonuclease, TatD-related; SPTR: Hydrolase, TatD family; TIGRFAM: Deoxyribonuclease, TatD Mg-dependent, prokaryote; IMG reference gene:2504774227; PFAM: TatD related DNase; TIGRFAM: hydrolase, TatD family. | Valyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily. | 0.412 |
| AEE52665.1 | ychF | Halhy_4832 | Halhy_6082 | Hydrolase, TatD family; COGs: COG0084 Mg-dependent DNase; InterPro IPR015991:IPR001130; KEGG: cpi:Cpin_0246 hydrolase, TatD family; PFAM: Deoxyribonuclease, TatD-related; SPTR: Hydrolase, TatD family; TIGRFAM: Deoxyribonuclease, TatD Mg-dependent, prokaryote; IMG reference gene:2504774227; PFAM: TatD related DNase; TIGRFAM: hydrolase, TatD family. | GTP-binding protein YchF; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner. | 0.417 |
| AEE52666.1 | AEE52665.1 | Halhy_4833 | Halhy_4832 | Ribonuclease H-related protein; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase H family. | Hydrolase, TatD family; COGs: COG0084 Mg-dependent DNase; InterPro IPR015991:IPR001130; KEGG: cpi:Cpin_0246 hydrolase, TatD family; PFAM: Deoxyribonuclease, TatD-related; SPTR: Hydrolase, TatD family; TIGRFAM: Deoxyribonuclease, TatD Mg-dependent, prokaryote; IMG reference gene:2504774227; PFAM: TatD related DNase; TIGRFAM: hydrolase, TatD family. | 0.536 |
| gltX | AEE52665.1 | Halhy_2744 | Halhy_4832 | glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. | Hydrolase, TatD family; COGs: COG0084 Mg-dependent DNase; InterPro IPR015991:IPR001130; KEGG: cpi:Cpin_0246 hydrolase, TatD family; PFAM: Deoxyribonuclease, TatD-related; SPTR: Hydrolase, TatD family; TIGRFAM: Deoxyribonuclease, TatD Mg-dependent, prokaryote; IMG reference gene:2504774227; PFAM: TatD related DNase; TIGRFAM: hydrolase, TatD family. | 0.456 |
| gltX | lepA | Halhy_2744 | Halhy_1598 | glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. | GTP-binding protein lepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | 0.633 |
| gltX | metG | Halhy_2744 | Halhy_2408 | glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. | Methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | 0.927 |
| gltX | nusA | Halhy_2744 | Halhy_3328 | glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. | NusA antitermination factor; Participates in both transcription termination and antitermination. | 0.546 |
| gltX | rpsI | Halhy_2744 | Halhy_2729 | glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. | COGs: COG0103 Ribosomal protein S9; InterPro IPR000754; KEGG: dfe:Dfer_3496 30S ribosomal protein S9; PFAM: Ribosomal protein S9; SPTR: 30S ribosomal protein S9; IMG reference gene:2504772100; PFAM: Ribosomal protein S9/S16; Belongs to the universal ribosomal protein uS9 family. | 0.540 |
| gltX | valS | Halhy_2744 | Halhy_0087 | glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. | Valyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily. | 0.574 |
| gltX | ychF | Halhy_2744 | Halhy_6082 | glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. | GTP-binding protein YchF; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner. | 0.731 |
| lepA | AEE52665.1 | Halhy_1598 | Halhy_4832 | GTP-binding protein lepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | Hydrolase, TatD family; COGs: COG0084 Mg-dependent DNase; InterPro IPR015991:IPR001130; KEGG: cpi:Cpin_0246 hydrolase, TatD family; PFAM: Deoxyribonuclease, TatD-related; SPTR: Hydrolase, TatD family; TIGRFAM: Deoxyribonuclease, TatD Mg-dependent, prokaryote; IMG reference gene:2504774227; PFAM: TatD related DNase; TIGRFAM: hydrolase, TatD family. | 0.416 |
| lepA | gltX | Halhy_1598 | Halhy_2744 | GTP-binding protein lepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. | 0.633 |
