Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
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AEE52677.1COGs: COG1132 ABC-type multidrug transport system ATPase and permease components; InterPro IPR003593:IPR001140:IPR003439; KEGG: app:CAP2UW1_2784 ABC transporter related; PFAM: ABC transporter-like; ABC transporter, transmembrane region; PRIAM: Xenobiotic-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: ABC transporter related; IMG reference gene:2504774240; PFAM: ABC transporter transmembrane region; ABC transporter. (613 aa)    
Predicted Functional Partners:
dnaK
Chaperone protein dnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
  
 0.658
AEE53655.1
Heat shock protein 70; COGs: COG0443 Molecular chaperone; InterPro IPR013126; KEGG: phe:Phep_3231 Fe-S protein assembly chaperone HscA; PFAM: Heat shock protein 70; SPTR: Heat shock protein 70; IMG reference gene:2504775230; PFAM: Hsp70 protein; TIGRFAM: Fe-S protein assembly chaperone HscA.
  
 0.646
AEE49932.1
AAA ATPase central domain protein; COGs: COG1222 ATP-dependent 26S proteasome regulatory subunit; InterPro IPR003593:IPR003959; KEGG: sus:Acid_2303 ATPase central domain-containing protein; PFAM: ATPase, AAA-type, core; SMART: ATPase, AAA+ type, core; SPTR: AAA ATPase, central domain protein; IMG reference gene:2504771414; PFAM: ATPase family associated with various cellular activities (AAA).
  
 
  0.606
AEE52920.1
Heat shock protein 70; COGs: COG0443 Molecular chaperone; InterPro IPR013126; KEGG: sli:Slin_5724 TIR protein; PFAM: Heat shock protein 70; SPTR: TIR protein; IMG reference gene:2504774492; PFAM: Hsp70 protein.
  
 0.600
AEE51863.1
COGs: COG0172 Seryl-tRNA synthetase; InterPro IPR015866:IPR002314:IPR002317; KEGG: coc:Coch_0734 seryl-tRNA synthetase; PFAM: Aminoacyl-tRNA synthetase, class II (G/ H/ P/ S), conserved region; Seryl-tRNA synthetase, class IIa, N-terminal; PRIAM: Serine--tRNA ligase; SPTR: Serine--tRNA ligase; TIGRFAM: Seryl-tRNA synthetase, class IIa; IMG reference gene:2504773400; PFAM: Seryl-tRNA synthetase N-terminal domain; tRNA synthetase class II core domain (G, H, P, S and T); TIGRFAM: seryl-tRNA synthetase.
 
   
 0.520
dnaJ
Chaperone protein dnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]
  
 
 0.503
AEE53994.1
COGs: COG0464 ATPase of the AAA+ class; InterProIPR001440:IPR013105:IPR003959:IPR019734:IPR 003593; KEGG: ote:Oter_1429 ATPase central domain-containing protein; PFAM: ATPase, AAA-type, core; Tetratricopeptide TPR2; Tetratricopeptide TPR-1; PRIAM: Microtubule-severing ATPase; SMART: ATPase, AAA+ type, core; Tetratricopeptide repeat; SPTR: AAA ATPase central domain protein; IMG reference gene:2504775574; PFAM: ATPase family associated with various cellular activities (AAA).
 
 
 0.491
AEE52678.1
RNA polymerase, sigma-24 subunit, ECF subfamily; COGs: COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog; InterPro IPR014284:IPR014327:IPR007627:IPR013249; KEGG: dfe:Dfer_4122 RNA polymerase, sigma-24 subunit, ECF subfamily; PFAM: RNA polymerase sigma factor 70, region 4 type 2; RNA polymerase sigma-70 region 2; SPTR: RNA polymerase, sigma-24 subunit, ECF subfamily; TIGRFAM: RNA polymerase sigma-70, Bacteroidetes type; RNA polymerase sigma-70; IMG reference gene:2504774241; PFAM: Sigma-70, region 4; Sigma-70 region 2; TIGRFAM: RNA polymerase sigma factor, si [...]
       0.488
adk
Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.
  
 
 0.484
AEE49827.1
3-oxoacyl-(acyl-carrier-protein) reductase; COGs: COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase); InterPro IPR002198; KEGG: mtt:Ftrac_3635 3-oxoacyl-(acyl-carrier-protein) reductase; PFAM: Short-chain dehydrogenase/reductase SDR; PRIAM: 3-oxoacyl-[acyl-carrier-protein] reductase; SPTR: 3-oxoacyl-(Acyl-carrier-protein) reductase; IMG reference gene:2504771303; PFAM: short chain dehydrogenase.
  
 
  0.436
Your Current Organism:
Haliscomenobacter hydrossis
NCBI taxonomy Id: 760192
Other names: H. hydrossis DSM 1100, Haliscomenobacter hydrossis DSM 1100
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