Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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[Homology]
Score
AEE52684.1Queuosine biosynthesis protein QueD; COGs: COG0720 6-pyruvoyl-tetrahydropterin synthase; InterPro IPR007115; KEGG: vex:VEA_003152 queuosine biosynthesis QueD PTPS-I; PFAM: 6-pyruvoyl tetrahydropterin synthase-related; SPTR: 6-pyruvoyl-tetrahydropterin synthase; TIGRFAM: queuosine biosynthesis protein QueD; IMG reference gene:2504774247; PFAM: 6-pyruvoyl tetrahydropterin synthase; TIGRFAM: queuosine biosynthesis protein QueD; 6-pyruvoyl tetrahydropterin synthase/QueD family protein. (118 aa)    
Predicted Functional Partners:
queE
Hypothetical protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
 
 
 0.994
folE
COGs: COG0302 GTP cyclohydrolase I; HAMAP: GTP cyclohydrolase I; InterPro IPR001474:IPR020602; KEGG: cts:Ctha_0487 GTP cyclohydrolase I; PFAM: GTP cyclohydrolase I/Nitrile oxidoreductase; PRIAM: GTP cyclohydrolase I; SPTR: GTP cyclohydrolase 1 2; TIGRFAM: GTP cyclohydrolase I; IMG reference gene:2504770198; PFAM: GTP cyclohydrolase I; TIGRFAM: GTP cyclohydrolase I.
  
 
 0.968
AEE48088.1
COGs: COG3540 Phosphodiesterase/alkaline phosphatase D; InterPro IPR018946:IPR006311; KEGG: ava:Ava_2698 twin-arginine translocation pathway signal; PFAM: Alkaline phosphatase D-related; SPTR: All0207 protein; IMG reference gene:2504769527; PFAM: PhoD-like phosphatase.
     
  0.900
AEE48367.1
COGs: COG1785 Alkaline phosphatase; InterPro IPR001952; KEGG: alkaline phosphatase; PFAM: Alkaline phosphatase; PRIAM: Alkaline phosphatase; SMART: Alkaline phosphatase; SPTR: Alkaline phosphatase; IMG reference gene:2504769813; PFAM: Alkaline phosphatase; Belongs to the alkaline phosphatase family.
     
  0.900
AEE49081.1
Hypothetical protein; COGs: COG3540 Phosphodiesterase/alkaline phosphatase D; KEGG: sli:Slin_5893 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504770545; PFAM: PhoD-like phosphatase.
     
  0.900
AEE52072.1
COGs: COG1785 Alkaline phosphatase; InterPro IPR001952; KEGG: alkaline phosphatase; PFAM: Alkaline phosphatase; PRIAM: Alkaline phosphatase; SMART: Alkaline phosphatase; SPTR: Alkaline phosphatase; IMG reference gene:2504773613; PFAM: Alkaline phosphatase; Belongs to the alkaline phosphatase family.
     
  0.900
AEE52685.1
Amidinotransferase; COGs: COG4874 Uncharacterized protein containing a pentein-type domain; InterPro IPR003198; KEGG: zpr:ZPR_3843 predicted amidinotransferase; PFAM: Amidinotransferase; SPTR: Amidinotransferase; manually curated; IMG reference gene:2504774248.
       0.551
cysS
COGs: COG0215 Cysteinyl-tRNA synthetase; InterPro IPR002308:IPR015803:IPR015273; KEGG: gfo:GFO_2741 cysteinyl-tRNA synthetase; PFAM: Cysteinyl-tRNA synthetase, class Ia, N-terminal; Cysteinyl-tRNA synthetase, class Ia, DALR; PRIAM: Cysteine--tRNA ligase; SPTR: Cysteinyl-tRNA synthetase; TIGRFAM: Cysteinyl-tRNA synthetase, class Ia; IMG reference gene:2504772726; PFAM: tRNA synthetases class I (C) catalytic domain; DALR domain; TIGRFAM: cysteinyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family.
  
  
 0.513
AEE52105.1
MazG family protein; COGs: COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like (predicted pyrophosphatase) domain; InterPro IPR004518:IPR011551; KEGG: MazG family protein; PFAM: NTP pyrophosphohydrolase MazG, putative catalytic core; SPTR: MazG family protein; TIGRFAM: NTP pyrophosphohydrolase MazG, bacterial; IMG reference gene:2504773647; PFAM: MazG nucleotide pyrophosphohydrolase domain; TIGRFAM: MazG family protein.
 
  
 0.482
hisI
COGs: COG0139 Phosphoribosyl-AMP cyclohydrolase; HAMAP: Histidine biosynthesis bifunctional protein hisIE; InterPro IPR008179:IPR002496; KEGG: mtt:Ftrac_3210 phosphoribosyl-ATP diphosphatase; PFAM: Phosphoribosyl-AMP cyclohydrolase; Phosphoribosyl-ATP pyrophosphohydrolase; SPTR: Phosphoribosyl-ATP diphosphatase; TIGRFAM: Phosphoribosyl-ATP pyrophosphohydrolase; IMG reference gene:2504773196; PFAM: Phosphoribosyl-ATP pyrophosphohydrolase; Phosphoribosyl-AMP cyclohydrolase; TIGRFAM: phosphoribosyl-ATP pyrophosphohydrolase; In the N-terminal section; belongs to the PRA-CH family.
     
 0.478
Your Current Organism:
Haliscomenobacter hydrossis
NCBI taxonomy Id: 760192
Other names: H. hydrossis DSM 1100, Haliscomenobacter hydrossis DSM 1100
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