Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEE52720.1Restriction endonuclease, type I, EcoRI, R subunit/Type III; COGs: COG0610 Type I site-specific restriction-modification system R (restriction) subunit and related helicase; InterPro IPR007409:IPR006935:IPR014001; KEGG: chu:CHU_2936 restriction enzyme type I helicase subunit; type I restriction enzyme HsdR; PFAM: Restriction endonuclease, type I, EcoRI, R subunit/Type III, Res subunit, N-terminal; Restriction endonuclease, type I, R subunit/Type III, Res subunit; SMART: DEAD-like helicase, N-terminal; SPTR: Restriction enzyme type I helicase subunit; type I restriction enzyme HsdR; IMG [...] (1031 aa)    
Predicted Functional Partners:
AEE52721.1
Restriction modification system DNA specificity domain protein; COGs: COG0732 Restriction endonuclease S subunits; InterPro IPR000055; KEGG: putative type I site-specific restriction-modification system, S subunit; PFAM: Restriction endonuclease, type I, S subunit, EcoBI; SPTR: Putative type I site-specific restriction-modification system, S subunit; IMG reference gene:2504774287; PFAM: Type I restriction modification DNA specificity domain.
 
  
 0.973
AEE50067.1
Restriction modification system DNA specificity domain protein; COGs: COG0732 Restriction endonuclease S subunits; InterPro IPR000055; KEGG: aav:Aave_3358 restriction modification system DNA specificity subunit; PFAM: Restriction endonuclease, type I, S subunit, EcoBI; SPTR: Restriction modification system DNA specificity domain protein; IMG reference gene:2504771551; PFAM: Type I restriction modification DNA specificity domain.
 
  
 0.887
AEE50068.1
N-6 DNA methylase; COGs: COG0286 Type I restriction-modification system methyltransferase subunit; InterPro IPR003356; KEGG: kvu:EIO_2897 type I restriction-modification system methyltransferase subunit; PFAM: DNA methylase, adenine-specific; SPTR: Type I restriction-modification system methyltransferase subunit; IMG reference gene:2504771552; PFAM: N-6 DNA Methylase; HsdM N-terminal domain.
 
  
 0.881
AEE52722.1
N-6 DNA methylase; COGs: COG0286 Type I restriction-modification system methyltransferase subunit; InterPro IPR003356; KEGG: chu:CHU_2941 restriction/modification methyltransferase; PFAM: DNA methylase, adenine-specific; SPTR: Restriction/modification methyltransferase; IMG reference gene:2504774288; PFAM: N-6 DNA Methylase; HsdM N-terminal domain.
 
  
 0.881
AEE48674.1
Restriction modification system DNA specificity domain protein; COGs: COG0732 Restriction endonuclease S subunits; InterPro IPR000055; KEGG: gbm:Gbem_3569 type I restriction-modification system DNA specificity subunit; PFAM: Restriction endonuclease, type I, S subunit, EcoBI; SPTR: Type I restriction-modification system DNA specificity subunit; IMG reference gene:2504770126; PFAM: Type I restriction modification DNA specificity domain.
 
  
 0.581
AEE49372.1
Restriction modification system DNA specificity domain protein; COGs: COG0732 Restriction endonuclease S subunits; InterPro IPR000055; KEGG: mmq:MmarC5_1170 restriction modification system DNA specificity subunit; PFAM: Restriction endonuclease, type I, S subunit, EcoBI; SPTR: Restriction modification system DNA specificity domain; IMG reference gene:2504770839; PFAM: Type I restriction modification DNA specificity domain.
  
  
 0.546
AEE48675.1
Death-on-curing family protein; COGs: COG3943 Virulence protein; InterPro IPR003812:IPR006440; KEGG: noc:Noc_1805 death-on-curing protein; PFAM: Filamentation induced by cAMP/death on curing, related; SPTR: Virulence protein; TIGRFAM: Death-on-curing protein; IMG reference gene:2504770127; PFAM: Fic/DOC family; TIGRFAM: death-on-curing family protein.
  
    0.539
AEE51087.1
N-6 DNA methylase; COGs: COG0286 Type I restriction-modification system methyltransferase subunit; InterPro IPR003356; KEGG: lby:Lbys_0413 N-6 DNA methylase; PFAM: DNA methylase, adenine-specific; SPTR: N-6 DNA methylase family protein; IMG reference gene:2504772607; PFAM: N-6 DNA Methylase.
  
  
 0.498
AEE53379.1
KEGG: nde:NIDE3670 DNA modification methylase; SPTR: DNA modification methylase; IMG reference gene:2504774953; PFAM: Eco57I restriction endonuclease.
  
  
 0.498
AEE52719.1
Hypothetical protein; IMG reference gene:2504774285.
       0.493
Your Current Organism:
Haliscomenobacter hydrossis
NCBI taxonomy Id: 760192
Other names: H. hydrossis DSM 1100, Haliscomenobacter hydrossis DSM 1100
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