Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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gene neighborhood
gene co-occurrence
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AEE52741.1Putative two component, sigma54 specific, transcriptional regulator; COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR001789:IPR002078:IPR003593; KEGG: ctc:CTC02322 transcriptional response regulator; PFAM: RNA polymerase sigma factor 54, interaction; Signal transduction response regulator, receiver region; SMART: ATPase, AAA+ type, core; Signal transduction response regulator, receiver region; SPTR: Transcriptional response regulator; IMG reference gene:2504774307; PFAM: Response regulator receiver domain; Sigma-54 int [...] (532 aa)    
Predicted Functional Partners:
AEE53076.1
Putative two component, sigma54 specific, transcriptional regulator; COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR001789:IPR002078:IPR003593; KEGG: dvu:DVU2934 sigma-54 dependent transcriptional regulator/response regulator; PFAM: RNA polymerase sigma factor 54, interaction; Signal transduction response regulator, receiver region; SMART: ATPase, AAA+ type, core; SPTR: Sigma-54 dependent transcriptional regulator/response regulator; IMG reference gene:2504774648; PFAM: Response regulator receiver domain; Sigma-54 int [...]
  
  
 
0.917
AEE49507.1
COGs: COG1508 DNA-directed RNA polymerase specialized sigma subunit sigma54 homolog; InterPro IPR000394:IPR007046:IPR007634; KEGG: dfe:Dfer_2750 RNA polymerase, sigma 54 subunit, RpoN; PFAM: RNA polymerase sigma factor 54, DNA-binding; RNA polymerase sigma factor 54, core-binding; SPTR: RNA polymerase, sigma 54 subunit, RpoN; TIGRFAM: RNA polymerase sigma factor 54; IMG reference gene:2504770977; PFAM: Sigma-54 factor, Activator interacting domain (AID); Sigma-54, DNA binding domain; Sigma-54 factor, core binding domain; TIGRFAM: RNA polymerase sigma-54 factor.
 
  
 0.787
AEE50459.1
COGs: COG1508 DNA-directed RNA polymerase specialized sigma subunit sigma54 homolog; InterPro IPR000394:IPR007046:IPR007634; KEGG: cpi:Cpin_0852 RNA polymerase, sigma 54 subunit, RpoN; PFAM: RNA polymerase sigma factor 54, DNA-binding; RNA polymerase sigma factor 54, core-binding; SPTR: RNA polymerase, sigma 54 subunit, RpoN; TIGRFAM: RNA polymerase sigma factor 54; manually curated; IMG reference gene:2504771960; PFAM: Sigma-54 factor, Activator interacting domain (AID); Sigma-54, DNA binding domain; Sigma-54 factor, core binding domain; TIGRFAM: RNA polymerase sigma-54 factor.
 
  
 0.786
AEE52739.1
Hypothetical protein; IMG reference gene:2504774305.
       0.773
AEE52740.1
Hypothetical protein; IMG reference gene:2504774306.
       0.773
AEE52738.1
Hypothetical protein; IMG reference gene:2504774304.
       0.746
AEE52737.1
Hypothetical protein; IMG reference gene:2504774303.
       0.685
AEE52742.1
Hypothetical protein; IMG reference gene:2504774308.
       0.678
AEE52899.1
Signal transduction histidine kinase with CheB and CheR activity; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.
  
 
 0.646
AEE53486.1
PAS/PAC sensor hybrid histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterProIPR000014:IPR003661:IPR003594:IPR001789:IPR 013656:IPR013767; KEGG: ppn:Palpr_2639 pas/pac sensor hybrid histidine kinase; PFAM: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; PAS fold-4; PAS fold; Signal transduction response regulator, receiver region; SMART: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; PAS; Signal transduction response reg [...]
  
 
 0.514
Your Current Organism:
Haliscomenobacter hydrossis
NCBI taxonomy Id: 760192
Other names: H. hydrossis DSM 1100, Haliscomenobacter hydrossis DSM 1100
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