STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
AEE52768.1Histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterProIPR011110:IPR011123:IPR003661:IPR003594:IPR 001789:IPR000005:IPR018060; KEGG: cpi:Cpin_5544 histidine kinase; PFAM: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; Two component regulator three Y; Two component regulator propeller; Signal transduction response regulator, receiver region; Helix-turn-helix, AraC type; SMART: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor regio [...] (1368 aa)    
Predicted Functional Partners:
AEE53486.1
PAS/PAC sensor hybrid histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterProIPR000014:IPR003661:IPR003594:IPR001789:IPR 013656:IPR013767; KEGG: ppn:Palpr_2639 pas/pac sensor hybrid histidine kinase; PFAM: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; PAS fold-4; PAS fold; Signal transduction response regulator, receiver region; SMART: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; PAS; Signal transduction response reg [...]
 
 
0.973
AEE49532.1
Hpt sensor hybrid histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003661:IPR003594:IPR001789:IPR008207; KEGG: cts:Ctha_0019 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; Signal transduction response regulator, receiver region; Signal transduction histidine kinase, phosphotransfer (Hpt) region; SMART: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; Signal transductio [...]
 
 
0.966
AEE52172.1
COGs: COG0642 Signal transduction histidine kinase; InterProIPR013767:IPR003661:IPR003594:IPR001789:IPR 008207:IPR000014:IPR001610; KEGG: sli:Slin_6270 multi-sensor hybrid histidine kinase; PFAM: Signal transduction response regulator, receiver region; ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; PAS fold; Signal transduction histidine kinase, phosphotransfer (Hpt) region; SMART: Signal transduction response regulator, receiver region; ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgro [...]
 
 
0.962
AEE49936.1
Adenylate/guanylate cyclase; COGs: COG0642 Signal transduction histidine kinase; InterProIPR003661:IPR003594:IPR001789:IPR001054:IPR 011110:IPR011123; KEGG: sde:Sde_0667 response regulator receiver domain-containing protein; PFAM: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; Two component regulator three Y; Two component regulator propeller; Signal transduction response regulator, receiver region; Adenylyl cyclase class-3/4/guanylyl cyclase; SMART: Signal transduction response regulator, receiver region; ATP-bin [...]
 
 
0.954
AEE50837.1
Adenylate/guanylate cyclase; COGs: COG0642 Signal transduction histidine kinase; InterProIPR003661:IPR003594:IPR001789:IPR001054:IPR 011110:IPR011123; KEGG: ter:Tery_2729 adenylate/guanylate cyclase; PFAM: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; Two component regulator three Y; Two component regulator propeller; Signal transduction response regulator, receiver region; Adenylyl cyclase class-3/4/guanylyl cyclase; SMART: Signal transduction response regulator, receiver region; ATP-binding region, ATPase-like; [...]
 
 
0.954
AEE52899.1
Signal transduction histidine kinase with CheB and CheR activity; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.
 
 
0.953
AEE48310.1
Integral membrane sensor hybrid histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterProIPR011110:IPR011123:IPR003661:IPR003594:IPR 001789:IPR000005:IPR018060; KEGG: bth:BT_4663 two-component system sensor histidine kinase/response; PFAM: Signal transduction response regulator, receiver region; ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; Two component regulator three Y; Two component regulator propeller; Helix-turn-helix, AraC type; SMART: Signal transduction response regulator, receiver r [...]
 
 
0.943
AEE52718.1
Histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterProIPR011110:IPR011123:IPR003661:IPR003594:IPR 001789:IPR000005:IPR018060; KEGG: cpi:Cpin_6165 histidine kinase; PFAM: ATP-binding region, ATPase-like; Two component regulator three Y; Two component regulator propeller; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; Signal transduction response regulator, receiver region; Helix-turn-helix, AraC type; SMART: Signal transduction response regulator, receiver region; ATP-binding region, ATPase-like; Signal transduction histidi [...]
 
 
0.930
AEE53102.1
Histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterProIPR011110:IPR011123:IPR003661:IPR003594:IPR 001789:IPR000005:IPR018060; KEGG: phe:Phep_1317 ATP-binding region ATPase domain protein; PFAM: ATP-binding region, ATPase-like; Two component regulator three Y; Two component regulator propeller; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; Signal transduction response regulator, receiver region; Helix-turn-helix, AraC type; SMART: Signal transduction response regulator, receiver region; ATP-binding region, ATPase-like; Sig [...]
 
 
0.930
AEE49986.1
Histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterProIPR003661:IPR003594:IPR001789:IPR018060:IPR 011110:IPR011123:IPR000005; KEGG: histidine kinase; PFAM: ATP-binding region, ATPase-like; Two component regulator three Y; Two component regulator propeller; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; Signal transduction response regulator, receiver region; Helix-turn-helix, AraC type; SMART: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; Signal tran [...]
 
 
0.923
Your Current Organism:
Haliscomenobacter hydrossis
NCBI taxonomy Id: 760192
Other names: H. hydrossis DSM 1100, Haliscomenobacter hydrossis DSM 1100
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