Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
AEE52811.1Protein of unknown function DUF2490; InterPro IPR019619; KEGG: hypothetical protein; PFAM: Protein of unknown function DUF2490; SPTR: Putative uncharacterized protein; IMG reference gene:2504774378; PFAM: Protein of unknown function (DUF2490). (250 aa)    
Predicted Functional Partners:
AEE52810.1
Sodium/hydrogen exchanger; COGs: COG3263 NhaP-type Na+/H+ and K+/H+ antiporter with a unique C-terminal domain; InterPro IPR006153:IPR006037; KEGG: potassium/proton antiporter, cpa1 family; PFAM: Cation/H+ exchanger; Regulator of K+ conductance, C-terminal; SPTR: Potassium/proton antiporter, CPA1 family; IMG reference gene:2504774377; PFAM: Sodium/hydrogen exchanger family; TrkA-C domain.
       0.636
AEE52812.1
Hypothetical protein; IMG reference gene:2504774379.
       0.473
AEE52808.1
Hypothetical protein; IMG reference gene:2504774375.
       0.450
AEE52809.1
Hypothetical protein; COGs: COG0308 Aminopeptidase N; KEGG: gau:GAU_2558 hypothetical protein; SPTR: Putative aminopeptidase; IMG reference gene:2504774376.
       0.450
AEE52813.1
KEGG: sli:Slin_1755 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504774380; PFAM: DoxX.
 
     0.422
Your Current Organism:
Haliscomenobacter hydrossis
NCBI taxonomy Id: 760192
Other names: H. hydrossis DSM 1100, Haliscomenobacter hydrossis DSM 1100
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