Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AEE52832.13-oxoadipate enol-lactonase; COGs: COG0596 hydrolase or acyltransferase (alpha/beta hydrolase superfamily); InterPro IPR000073:IPR003779:IPR012790:IPR012788; KEGG: azc:AZC_1444 beta-ketoadipate enol-lactone hydrolase protein; PFAM: Carboxymuconolactone decarboxylase; Alpha/beta hydrolase fold-1; PRIAM: 3-oxoadipate enol-lactonase., 4-carboxymuconolactone decarboxylase; SPTR: Beta-ketoadipate enol-lactone hydrolase protein; TIGRFAM: 3-oxoadipate enol-lactonase; 4-carboxymuconolactone decarboxylase; IMG reference gene:2504774399; PFAM: Ndr family; Carboxymuconolactone decarboxylase famil [...] (384 aa)    
Predicted Functional Partners:
AEE52827.1
3-carboxy-cis,cis-muconate cycloisomerase; COGs: COG0015 Adenylosuccinate lyase; InterPro IPR000362:IPR019468:IPR012789; KEGG: avn:Avin_38190 3-carboxy-cis,cis-muconate cycloisomerase; PFAM: Fumarate lyase; Adenylosuccinate lyase, C-terminal; PRIAM: 3-carboxy-cis,cis-muconate cycloisomerase; SPTR: 3-carboxy-cis,cis-muconate cycloisomerase; TIGRFAM: 3-carboxy-cis,cis-muconate cycloisomerase; IMG reference gene:2504774394; PFAM: Lyase; Adenylosuccinate lyase C-terminus; TIGRFAM: 3-carboxy-cis,cis-muconate cycloisomerase.
 
 
 0.986
AEE52833.1
4-hydroxybenzoate 3-monooxygenase; COGs: COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductase; InterPro IPR002938; KEGG: sli:Slin_1534 4-hydroxybenzoate 3-monooxygenase; PFAM: Monooxygenase, FAD-binding; PRIAM: 4-hydroxybenzoate 3-monooxygenase; SPTR: 4-hydroxybenzoate 3-monooxygenase; IMG reference gene:2504774400; PFAM: FAD binding domain; TIGRFAM: 4-hydroxybenzoate 3-monooxygenase.
 
 0.958
AEE52830.1
COGs: COG3485 Protocatechuate 3 4-dioxygenase beta subunit; InterPro IPR000627:IPR012786; KEGG: vap:Vapar_4465 protocatechuate 3,4-dioxygenase, alpha subunit; PFAM: Intradiol ring-cleavage dioxygenase, C-terminal; PRIAM: Protocatechuate 3,4-dioxygenase; SPTR: Protocatechuate 3,4-dioxygenase, alpha subunit; TIGRFAM: Protocatechuate 3,4-dioxygenase, alpha subunit; IMG reference gene:2504774397.
 
  
 0.952
AEE52831.1
COGs: COG3485 Protocatechuate 3 4-dioxygenase beta subunit; InterPro IPR000627:IPR012785; KEGG: sli:Slin_1538 protocatechuate 3,4-dioxygenase, beta subunit; PFAM: Intradiol ring-cleavage dioxygenase, C-terminal; PRIAM: Protocatechuate 3,4-dioxygenase; SPTR: Protocatechuate 3,4-dioxygenase, beta subunit; TIGRFAM: Protocatechuate 3,4-dioxygenase, beta subunit; IMG reference gene:2504774398; PFAM: Protocatechuate 3,4-dioxygenase beta subunit N terminal; Dioxygenase; TIGRFAM: protocatechuate 3,4-dioxygenase, beta subunit.
 
  
 0.952
AEE53623.1
Protein of unknown function DUF849; COGs: COG3246 conserved hypothetical protein; InterPro IPR008567; KEGG: rbi:RB2501_11342 hypothetical protein; PFAM: Protein of unknown function DUF849, prokaryotic; SPTR: Putative uncharacterized protein; IMG reference gene:2504775198; PFAM: Prokaryotic protein of unknown function (DUF849).
 
  
  0.927
AEE52829.1
COGs: COG2057 Acyl CoA:acetate/3-ketoacid CoA transferase beta subunit; InterPro IPR004165:IPR012792:IPR012791; KEGG: sli:Slin_1533 3-oxoacid CoA-transferase, B subunit; PFAM: Coenzyme A transferase; PRIAM: 3-oxoacid CoA-transferase; SPTR: 3-oxoacid CoA-transferase, B subunit; TIGRFAM: 3-oxoacid CoA-transferase, subunit B; 3-oxoacid CoA-transferase, subunit A; IMG reference gene:2504774396; PFAM: Coenzyme A transferase; TIGRFAM: 3-oxoacid CoA-transferase, B subunit; 3-oxoacid CoA-transferase, A subunit.
 
  
 0.860
AEE52258.1
Intradiol ring-cleavage dioxygenase; COGs: COG3485 Protocatechuate 3 4-dioxygenase beta subunit; InterPro IPR000627; KEGG: pol:Bpro_1824 twin-arginine translocation pathway signal; PFAM: Intradiol ring-cleavage dioxygenase, C-terminal; SPTR: Catechol dioxygenase; IMG reference gene:2504773802; PFAM: Dioxygenase.
 
  
 0.776
AEE48377.1
FAD dependent oxidoreductase; COGs: COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductase; InterPro IPR006076; KEGG: sli:Slin_0336 monooxygenase FAD-binding protein; PFAM: FAD dependent oxidoreductase; SPTR: Monooxygenase FAD-binding protein; IMG reference gene:2504769823; PFAM: FAD binding domain.
 
 0.647
AEE52828.1
Beta-ketoadipyl CoA thiolase; COGs: COG0183 Acetyl-CoA acetyltransferase; InterPro IPR012793:IPR002155; KEGG: sli:Slin_1532 beta-ketoadipyl CoA thiolase; PRIAM: 3-oxoadipyl-CoA thiolase; SPTR: Beta-ketoadipyl CoA thiolase; TIGRFAM: Beta-ketoadipyl CoA thiolase; Thiolase; IMG reference gene:2504774395; PFAM: Thiolase, C-terminal domain; Thiolase, N-terminal domain; TIGRFAM: acetyl-CoA acetyltransferases; 3-oxoadipyl-CoA thiolase; Belongs to the thiolase-like superfamily. Thiolase family.
 
  
 0.596
AEE52834.1
Hypothetical protein; IMG reference gene:2504774401.
       0.548
Your Current Organism:
Haliscomenobacter hydrossis
NCBI taxonomy Id: 760192
Other names: H. hydrossis DSM 1100, Haliscomenobacter hydrossis DSM 1100
Server load: low (16%) [HD]