| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AEE48200.1 | AEE51541.1 | Halhy_0288 | Halhy_3689 | COGs: COG0408 Coproporphyrinogen III oxidase; InterPro IPR001260; KEGG: dfe:Dfer_2369 coproporphyrinogen III oxidase; PFAM: Coproporphyrinogen III oxidase; PRIAM: Coproporphyrinogen oxidase; SPTR: Coproporphyrinogen oxidase; IMG reference gene:2504769643; PFAM: Coproporphyrinogen III oxidase. | Uncharacterized protein family UPF0093; COGs: COG1981 membrane protein; InterPro IPR005265; KEGG: lby:Lbys_1279 uncharacterized protein family upf0093; PFAM: Uncharacterised protein family UPF0093; SPTR: Uncharacterized protein family UPF0093; IMG reference gene:2504773070; PFAM: Uncharacterised protein family (UPF0093); TIGRFAM: TIGR00701 family protein. | 0.950 |
| AEE48200.1 | AEE52545.1 | Halhy_0288 | Halhy_4711 | COGs: COG0408 Coproporphyrinogen III oxidase; InterPro IPR001260; KEGG: dfe:Dfer_2369 coproporphyrinogen III oxidase; PFAM: Coproporphyrinogen III oxidase; PRIAM: Coproporphyrinogen oxidase; SPTR: Coproporphyrinogen oxidase; IMG reference gene:2504769643; PFAM: Coproporphyrinogen III oxidase. | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. | 0.575 |
| AEE48200.1 | ctaB | Halhy_0288 | Halhy_4877 | COGs: COG0408 Coproporphyrinogen III oxidase; InterPro IPR001260; KEGG: dfe:Dfer_2369 coproporphyrinogen III oxidase; PFAM: Coproporphyrinogen III oxidase; PRIAM: Coproporphyrinogen oxidase; SPTR: Coproporphyrinogen oxidase; IMG reference gene:2504769643; PFAM: Coproporphyrinogen III oxidase. | Protoheme IX farnesyltransferase; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group. | 0.417 |
| AEE48200.1 | hemE | Halhy_0288 | Halhy_5610 | COGs: COG0408 Coproporphyrinogen III oxidase; InterPro IPR001260; KEGG: dfe:Dfer_2369 coproporphyrinogen III oxidase; PFAM: Coproporphyrinogen III oxidase; PRIAM: Coproporphyrinogen oxidase; SPTR: Coproporphyrinogen oxidase; IMG reference gene:2504769643; PFAM: Coproporphyrinogen III oxidase. | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | 0.973 |
| AEE48200.1 | hemH | Halhy_0288 | Halhy_5067 | COGs: COG0408 Coproporphyrinogen III oxidase; InterPro IPR001260; KEGG: dfe:Dfer_2369 coproporphyrinogen III oxidase; PFAM: Coproporphyrinogen III oxidase; PRIAM: Coproporphyrinogen oxidase; SPTR: Coproporphyrinogen oxidase; IMG reference gene:2504769643; PFAM: Coproporphyrinogen III oxidase. | Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. | 0.764 |
| AEE48927.1 | AEE51541.1 | Halhy_1028 | Halhy_3689 | COGs: COG1239 Mg-chelatase subunit ChlI; KEGG: sli:Slin_0326 Mg-chelatase subunit ChlI-like protein; SPTR: Putative magnesium chelatase; IMG reference gene:2504770389. | Uncharacterized protein family UPF0093; COGs: COG1981 membrane protein; InterPro IPR005265; KEGG: lby:Lbys_1279 uncharacterized protein family upf0093; PFAM: Uncharacterised protein family UPF0093; SPTR: Uncharacterized protein family UPF0093; IMG reference gene:2504773070; PFAM: Uncharacterised protein family (UPF0093); TIGRFAM: TIGR00701 family protein. | 0.902 |
| AEE48927.1 | AEE52545.1 | Halhy_1028 | Halhy_4711 | COGs: COG1239 Mg-chelatase subunit ChlI; KEGG: sli:Slin_0326 Mg-chelatase subunit ChlI-like protein; SPTR: Putative magnesium chelatase; IMG reference gene:2504770389. | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. | 0.505 |
| AEE48927.1 | hemH | Halhy_1028 | Halhy_5067 | COGs: COG1239 Mg-chelatase subunit ChlI; KEGG: sli:Slin_0326 Mg-chelatase subunit ChlI-like protein; SPTR: Putative magnesium chelatase; IMG reference gene:2504770389. | Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. | 0.917 |
| AEE49255.1 | AEE50380.1 | Halhy_1360 | Halhy_2507 | 3-hydroxybutyryl-CoA epimerase; COGs: COG1250 3-hydroxyacyl-CoA dehydrogenase; InterPro IPR001753:IPR006176:IPR006108; KEGG: rmr:Rmar_1469 3-hydroxyacyl-CoA dehydrogenase NAD-binding protein; PFAM: 3-hydroxyacyl-CoA dehydrogenase, NAD binding; Crotonase, core; 3-hydroxyacyl-CoA dehydrogenase, C-terminal; PRIAM: 3-hydroxybutyryl-CoA epimerase; SPTR: 3-hydroxyacyl-CoA dehydrogenase NAD-binding protein; IMG reference gene:2504770721; PFAM: Enoyl-CoA hydratase/isomerase family; 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain. | Aconitate hydratase; COGs: COG1048 Aconitase A; InterPro IPR006248:IPR001030:IPR000573; KEGG: cpi:Cpin_2016 aconitate hydratase; PFAM: Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha; Aconitase A/isopropylmalate dehydratase small subunit, swivel; SPTR: Aconitate hydratase; TIGRFAM: Aconitase, mitochondrial-like; IMG reference gene:2504771876; PFAM: Aconitase C-terminal domain; Aconitase family (aconitate hydratase); TIGRFAM: aconitate hydratase, mitochondrial. | 0.841 |
| AEE49255.1 | hemH | Halhy_1360 | Halhy_5067 | 3-hydroxybutyryl-CoA epimerase; COGs: COG1250 3-hydroxyacyl-CoA dehydrogenase; InterPro IPR001753:IPR006176:IPR006108; KEGG: rmr:Rmar_1469 3-hydroxyacyl-CoA dehydrogenase NAD-binding protein; PFAM: 3-hydroxyacyl-CoA dehydrogenase, NAD binding; Crotonase, core; 3-hydroxyacyl-CoA dehydrogenase, C-terminal; PRIAM: 3-hydroxybutyryl-CoA epimerase; SPTR: 3-hydroxyacyl-CoA dehydrogenase NAD-binding protein; IMG reference gene:2504770721; PFAM: Enoyl-CoA hydratase/isomerase family; 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain. | Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. | 0.566 |
| AEE50380.1 | AEE49255.1 | Halhy_2507 | Halhy_1360 | Aconitate hydratase; COGs: COG1048 Aconitase A; InterPro IPR006248:IPR001030:IPR000573; KEGG: cpi:Cpin_2016 aconitate hydratase; PFAM: Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha; Aconitase A/isopropylmalate dehydratase small subunit, swivel; SPTR: Aconitate hydratase; TIGRFAM: Aconitase, mitochondrial-like; IMG reference gene:2504771876; PFAM: Aconitase C-terminal domain; Aconitase family (aconitate hydratase); TIGRFAM: aconitate hydratase, mitochondrial. | 3-hydroxybutyryl-CoA epimerase; COGs: COG1250 3-hydroxyacyl-CoA dehydrogenase; InterPro IPR001753:IPR006176:IPR006108; KEGG: rmr:Rmar_1469 3-hydroxyacyl-CoA dehydrogenase NAD-binding protein; PFAM: 3-hydroxyacyl-CoA dehydrogenase, NAD binding; Crotonase, core; 3-hydroxyacyl-CoA dehydrogenase, C-terminal; PRIAM: 3-hydroxybutyryl-CoA epimerase; SPTR: 3-hydroxyacyl-CoA dehydrogenase NAD-binding protein; IMG reference gene:2504770721; PFAM: Enoyl-CoA hydratase/isomerase family; 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain. | 0.841 |
| AEE50380.1 | hemH | Halhy_2507 | Halhy_5067 | Aconitate hydratase; COGs: COG1048 Aconitase A; InterPro IPR006248:IPR001030:IPR000573; KEGG: cpi:Cpin_2016 aconitate hydratase; PFAM: Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha; Aconitase A/isopropylmalate dehydratase small subunit, swivel; SPTR: Aconitate hydratase; TIGRFAM: Aconitase, mitochondrial-like; IMG reference gene:2504771876; PFAM: Aconitase C-terminal domain; Aconitase family (aconitate hydratase); TIGRFAM: aconitate hydratase, mitochondrial. | Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. | 0.570 |
| AEE51541.1 | AEE48200.1 | Halhy_3689 | Halhy_0288 | Uncharacterized protein family UPF0093; COGs: COG1981 membrane protein; InterPro IPR005265; KEGG: lby:Lbys_1279 uncharacterized protein family upf0093; PFAM: Uncharacterised protein family UPF0093; SPTR: Uncharacterized protein family UPF0093; IMG reference gene:2504773070; PFAM: Uncharacterised protein family (UPF0093); TIGRFAM: TIGR00701 family protein. | COGs: COG0408 Coproporphyrinogen III oxidase; InterPro IPR001260; KEGG: dfe:Dfer_2369 coproporphyrinogen III oxidase; PFAM: Coproporphyrinogen III oxidase; PRIAM: Coproporphyrinogen oxidase; SPTR: Coproporphyrinogen oxidase; IMG reference gene:2504769643; PFAM: Coproporphyrinogen III oxidase. | 0.950 |
| AEE51541.1 | AEE48927.1 | Halhy_3689 | Halhy_1028 | Uncharacterized protein family UPF0093; COGs: COG1981 membrane protein; InterPro IPR005265; KEGG: lby:Lbys_1279 uncharacterized protein family upf0093; PFAM: Uncharacterised protein family UPF0093; SPTR: Uncharacterized protein family UPF0093; IMG reference gene:2504773070; PFAM: Uncharacterised protein family (UPF0093); TIGRFAM: TIGR00701 family protein. | COGs: COG1239 Mg-chelatase subunit ChlI; KEGG: sli:Slin_0326 Mg-chelatase subunit ChlI-like protein; SPTR: Putative magnesium chelatase; IMG reference gene:2504770389. | 0.902 |
| AEE51541.1 | hemE | Halhy_3689 | Halhy_5610 | Uncharacterized protein family UPF0093; COGs: COG1981 membrane protein; InterPro IPR005265; KEGG: lby:Lbys_1279 uncharacterized protein family upf0093; PFAM: Uncharacterised protein family UPF0093; SPTR: Uncharacterized protein family UPF0093; IMG reference gene:2504773070; PFAM: Uncharacterised protein family (UPF0093); TIGRFAM: TIGR00701 family protein. | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | 0.439 |
| AEE51541.1 | hemH | Halhy_3689 | Halhy_5067 | Uncharacterized protein family UPF0093; COGs: COG1981 membrane protein; InterPro IPR005265; KEGG: lby:Lbys_1279 uncharacterized protein family upf0093; PFAM: Uncharacterised protein family UPF0093; SPTR: Uncharacterized protein family UPF0093; IMG reference gene:2504773070; PFAM: Uncharacterised protein family (UPF0093); TIGRFAM: TIGR00701 family protein. | Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. | 0.945 |
| AEE52545.1 | AEE48200.1 | Halhy_4711 | Halhy_0288 | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. | COGs: COG0408 Coproporphyrinogen III oxidase; InterPro IPR001260; KEGG: dfe:Dfer_2369 coproporphyrinogen III oxidase; PFAM: Coproporphyrinogen III oxidase; PRIAM: Coproporphyrinogen oxidase; SPTR: Coproporphyrinogen oxidase; IMG reference gene:2504769643; PFAM: Coproporphyrinogen III oxidase. | 0.575 |
| AEE52545.1 | AEE48927.1 | Halhy_4711 | Halhy_1028 | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. | COGs: COG1239 Mg-chelatase subunit ChlI; KEGG: sli:Slin_0326 Mg-chelatase subunit ChlI-like protein; SPTR: Putative magnesium chelatase; IMG reference gene:2504770389. | 0.505 |
| AEE52545.1 | hemE | Halhy_4711 | Halhy_5610 | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | 0.979 |
| AEE52545.1 | hemH | Halhy_4711 | Halhy_5067 | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. | Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. | 0.600 |
