STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sbcDExonuclease SbcCD subunit D; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family. (383 aa)    
Predicted Functional Partners:
OLZ53587.1
Exonuclease SbcC; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.999
OLZ55176.1
Flap endonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.987
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
   
 0.987
OLZ52537.1
DNA repair ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.986
OLZ42977.1
ATP-dependent DNA helicase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.976
OLZ50464.1
ATP-dependent helicase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.930
recA
Recombinase RecA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
  
 0.923
OLZ44878.1
Flap endonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.915
OLZ45348.1
Recombinase RecQ; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.913
OLZ43244.1
ATP-dependent DNA helicase RecQ; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.903
Your Current Organism:
Amycolatopsis coloradensis
NCBI taxonomy Id: 76021
Other names: A. coloradensis, ATCC 53629, Amycolatopsis coloradoensis, DSM 44225, IFO 15804, IMSNU 22096, JCM 9869, NBRC 15804, NRRL 3218
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