STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
vanBD-alanine--(R)-lactate ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. (347 aa)    
Predicted Functional Partners:
vanX
D-Ala-D-Ala dipeptidase VanX; Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide.
 
  
 0.993
OLZ52462.1
Lactate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
 
  
 0.981
murC
UDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family.
 
 0.962
murF
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily.
 
 0.945
OLZ44506.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.922
OLZ44518.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ATP-dependent AMP-binding enzyme family.
     
 0.911
murE
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily.
 
 
 0.897
OLZ44581.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.895
OLZ49036.1
Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family.
 
 
 0.891
murB
UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation.
 
 
 0.867
Your Current Organism:
Amycolatopsis coloradensis
NCBI taxonomy Id: 76021
Other names: A. coloradensis, ATCC 53629, Amycolatopsis coloradoensis, DSM 44225, IFO 15804, IMSNU 22096, JCM 9869, NBRC 15804, NRRL 3218
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.