STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
OLZ50479.1MBL fold metallo-hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (255 aa)    
Predicted Functional Partners:
OLZ56692.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
   
   0.875
rph
Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
  
 
 0.867
murI
Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis.
       0.782
OLZ50480.1
Non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
  
    0.782
OLZ45336.1
Ribonuclease E/G; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.765
OLZ50477.1
Rhomboid family intramembrane serine protease; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.703
rnpA
Ribonuclease P protein component; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
  
  
  0.698
OLZ50768.1
Arylamine N-acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.484
OLZ43707.1
Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.483
OLZ50464.1
ATP-dependent helicase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.481
Your Current Organism:
Amycolatopsis coloradensis
NCBI taxonomy Id: 76021
Other names: A. coloradensis, ATCC 53629, Amycolatopsis coloradoensis, DSM 44225, IFO 15804, IMSNU 22096, JCM 9869, NBRC 15804, NRRL 3218
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