STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
OLZ50725.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (497 aa)    
Predicted Functional Partners:
OLZ50724.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
       0.757
OLZ50726.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.756
OLZ50727.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
0.647
OLZ52599.1
DNA topoisomerase IV subunit B; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 
 0.554
gyrB
DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
    
 
 0.554
OLZ50723.1
Type VII secretion protein EccC; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.545
OLZ50728.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
       0.457
Your Current Organism:
Amycolatopsis coloradensis
NCBI taxonomy Id: 76021
Other names: A. coloradensis, ATCC 53629, Amycolatopsis coloradoensis, DSM 44225, IFO 15804, IMSNU 22096, JCM 9869, NBRC 15804, NRRL 3218
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.