STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
OLZ49338.1uroporphyrinogen-III synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (367 aa)    
Predicted Functional Partners:
hemC
Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
  
 0.986
OLZ51063.1
uroporphyrinogen-III C-methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.984
OLZ49453.1
MFS transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.964
OLZ49336.1
Nitrite reductase large subunit; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
 
  
 0.955
OLZ47769.1
Bifunctional uroporphyrinogen-III C-methyltransferase/uroporphyrinogen-III synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.954
OLZ49337.1
Nitrite reductase small subunit; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.947
hemE
Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
  
 
 0.945
OLZ49341.1
Uroporphyrinogen III synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
0.918
OLZ47771.1
Delta-aminolevulinic acid dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ALAD family.
  
 0.908
OLZ49334.1
Nitrite reductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
 
   
 0.903
Your Current Organism:
Amycolatopsis coloradensis
NCBI taxonomy Id: 76021
Other names: A. coloradensis, ATCC 53629, Amycolatopsis coloradoensis, DSM 44225, IFO 15804, IMSNU 22096, JCM 9869, NBRC 15804, NRRL 3218
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