STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEG15271.1PFAM: Histidinol dehydrogenase, prokaryotic-type; TIGRFAM: Histidinol dehydrogenase, prokaryotic-type; HAMAP: Histidinol dehydrogenase, prokaryotic-type; KEGG: dae:Dtox_0752 histidinol dehydrogenase. (435 aa)    
Predicted Functional Partners:
AEG15265.1
Histidine biosynthesis bifunctional protein hisIE; PFAM: Phosphoribosyl-AMP cyclohydrolase; Phosphoribosyl-ATP pyrophosphohydrolase; TIGRFAM: Phosphoribosyl-ATP pyrophosphohydrolase; HAMAP: Histidine biosynthesis bifunctional protein hisIE; KEGG: dae:Dtox_0758 phosphoribosyl-ATP diphosphatase.
  
 0.999
hisF
Imidazole glycerol phosphate synthase subunit hisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
  
 0.999
AEG15267.1
1-(5-phosphoribosyl)-5-((5- phosphoribosylamino)methylideneamino) imidazole-4-carboxamide isomerase; PFAM: Histidine biosynthesis; TIGRFAM: Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; HAMAP: 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase; KEGG: pth:PTH_2533 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase.
  
 0.999
AEG15268.1
TIGRFAM: Imidazole glycerol phosphate synthase, subunit H; HAMAP: Imidazole glycerol phosphate synthase, subunit H; KEGG: dae:Dtox_0755 imidazole glycerol phosphate synthase subunit HisH; PFAM: Glutamine amidotransferase class-I, C-terminal.
  
 0.999
AEG15269.1
HAMAP: Imidazoleglycerol-phosphate dehydratase; KEGG: dae:Dtox_0754 imidazoleglycerol-phosphate dehydratase; PFAM: Imidazoleglycerol-phosphate dehydratase.
  
 0.999
AEG15270.1
PFAM: Aminotransferase, class I/II; TIGRFAM: Histidinol-phosphate aminotransferase; HAMAP: Histidinol-phosphate aminotransferase; KEGG: pth:PTH_2537 histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase.
  
 0.999
hisG
ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
  
 0.998
AEG15901.1
Histidinol-phosphate aminotransferase; TIGRFAM: L-threonine-O-3-phosphate decarboxylase; HAMAP: Histidinol-phosphate aminotransferase; KEGG: pth:PTH_1314 histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase; PFAM: Aminotransferase, class I/II.
  
 0.975
AEG14729.1
KEGG: dau:Daud_1449 histidinol-phosphatase; TIGRFAM: Histidinol phosphate phosphatase, HisJ; PFAM: PHP, C-terminal.
 
 
 0.945
AEG15054.1
KEGG: tjr:TherJR_1575 histidinol phosphate phosphatase HisJ family; TIGRFAM: Histidinol phosphate phosphatase, HisJ; PFAM: PHP, C-terminal.
  
 
 0.938
Your Current Organism:
Desulfofundulus kuznetsovii
NCBI taxonomy Id: 760568
Other names: D. kuznetsovii DSM 6115, Desulfofundulus kuznetsovii DSM 6115, Desulfotomaculum kuznetsovii 17, Desulfotomaculum kuznetsovii DSM 6115
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