Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Score
AEG16698.1Diguanylate cyclase and metal dependent phosphohydrolase; TIGRFAM: Diguanylate cyclase, predicted; PAS; PFAM: CHASE4; HAMP linker domain; PAS fold-3; PAS fold-4; Diguanylate cyclase, predicted; Metal-dependent phosphohydrolase, HD region, subdomain; KEGG: drm:Dred_1552 diguanylate cyclase with PAS/PAC sensor; SMART: Diguanylate cyclase, predicted; PAS; Metal-dependent phosphohydrolase, HD region. (929 aa)    
Predicted Functional Partners:
AEG16706.1
Diguanylate cyclase/phosphodiesterase with CBS domains; TIGRFAM: Diguanylate cyclase, predicted; PFAM: Diguanylate phosphodiesterase, predicted; Cystathionine beta-synthase, core; Diguanylate cyclase, predicted; KEGG: dae:Dtox_1949 diguanylate cyclase/phosphodiesterase; SMART: Diguanylate phosphodiesterase, predicted; Diguanylate cyclase, predicted.
 
 
 0.961
AEG16405.1
TIGRFAM: Diguanylate cyclase, predicted; PAS; HDIG; PFAM: Diguanylate cyclase, predicted; PAS fold-4; Metal-dependent phosphohydrolase, HD region, subdomain; KEGG: chy:CHY_1875 sensory box protein; SMART: Diguanylate cyclase, predicted; PAS; Metal-dependent phosphohydrolase, HD region.
 
 
0.936
AEG15591.1
KEGG: tye:THEYE_A0182 response regulator receiver; PFAM: Signal transduction response regulator, receiver region; SMART: Signal transduction response regulator, receiver region.
  
 
 0.929
AEG14332.1
SMART: Diguanylate cyclase, predicted; TIGRFAM: Diguanylate cyclase, predicted; KEGG: dau:Daud_0690 diguanylate cyclase; PFAM: Diguanylate cyclase, predicted.
 
 
0.910
AEG16457.1
KEGG: pth:PTH_2640 signal transduction histidine kinase; PFAM: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; SMART: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; GAF.
  
 
 0.907
AEG16988.1
TIGRFAM: Diguanylate cyclase, predicted; PAS; HDIG; PFAM: Diguanylate cyclase, predicted; PAS fold-4; Metal-dependent phosphohydrolase, HD region, subdomain; KEGG: chy:CHY_1875 sensory box protein; SMART: Diguanylate cyclase, predicted; PAS; Metal-dependent phosphohydrolase, HD region.
 
 
0.891
AEG16312.1
Metal dependent phosphohydrolase; KEGG: swo:Swol_2407 HD domain-containing protein; PFAM: Metal-dependent phosphohydrolase, HD region, subdomain; SMART: Metal-dependent phosphohydrolase, HD region.
 
 
0.889
AEG15808.1
TIGRFAM: Diguanylate cyclase, predicted; PFAM: Diguanylate cyclase, predicted; KEGG: tal:Thal_0732 diguanylate cyclase with PAS/PAC, CBS and GAF sensors; SMART: Diguanylate cyclase, predicted.
 
 
0.875
AEG16840.1
TIGRFAM: Diguanylate cyclase, predicted; PFAM: Diguanylate cyclase, predicted; GAF; KEGG: pth:PTH_2757 hypothetical protein; SMART: Diguanylate cyclase, predicted; GAF.
 
 
0.871
AEG14212.1
TIGRFAM: HDIG; PFAM: Transcriptional regulator, histidine kinase sensor, N-terminal; GAF; Metal-dependent phosphohydrolase, HD region, subdomain; KEGG: mta:Moth_2150 metal dependent phosphohydrolase; SMART: Metal-dependent phosphohydrolase, HD region; GAF.
 
 
0.865
Your Current Organism:
Desulfofundulus kuznetsovii
NCBI taxonomy Id: 760568
Other names: D. kuznetsovii DSM 6115, Desulfofundulus kuznetsovii DSM 6115, Desulfotomaculum kuznetsovii 17, Desulfotomaculum kuznetsovii DSM 6115
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