STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEG17045.1Membrane protein insertase, YidC/Oxa1 family; KEGG: pth:PTH_2919 preprotein translocase subunit YidC; TIGRFAM: Membrane insertion protein, OxaA/YidC, core; PFAM: Membrane insertion protein, OxaA/YidC. (228 aa)    
Predicted Functional Partners:
secY
Preprotein translocase, SecY subunit; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.
  
 0.993
AEG16776.1
KEGG: dae:Dtox_3932 preprotein translocase subunit SecG; TIGRFAM: Preprotein translocase SecG subunit; PFAM: Preprotein translocase SecG subunit.
   
 0.991
AEG16567.1
KEGG: pth:PTH_0304 preprotein translocase subunit SecE; TIGRFAM: SecE subunit of protein translocation complex; PFAM: Protein secE/sec61-gamma protein.
  
 0.986
AEG17047.1
TIGRFAM: Ribonuclease P; HAMAP: Ribonuclease P; KEGG: drm:Dred_3328 ribonuclease P protein component; PFAM: Ribonuclease P.
  
  
 0.979
AEG17044.1
KEGG: pth:PTH_2918 RNA binding protein; PFAM: Single-stranded nucleic acid binding R3H; SMART: Single-stranded nucleic acid binding R3H.
  
  
 0.971
AEG17046.1
UPF0161 protein yidD; TIGRFAM: Protein of unknown function DUF37; HAMAP: Protein of unknown function DUF37; KEGG: ttm:Tthe_2755 protein of unknown function DUF37; PFAM: Protein of unknown function DUF37.
  
  
 0.967
AEG14284.1
Protein-export membrane protein SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.
  
 
 0.962
AEG16819.1
TIGRFAM: SecA protein; HAMAP: Protein translocase subunit secA; KEGG: pth:PTH_2753 preprotein translocase subunit SecA; PFAM: SecA DEAD-like; SecA preprotein cross-linking region; SecA Wing/Scaffold; SEC-C motif.
 
 
 0.955
AEG15689.1
TIGRFAM: Signal recognition particle, SRP; PFAM: Signal recognition particle, SRP54 subunit, GTPase; Signal recognition particle, SRP54 subunit, helical bundle; Signal recognition particle, SRP54 subunit, M-domain; KEGG: dae:Dtox_1196 signal recognition particle protein; SMART: ATPase, AAA+ type, core.
   
 0.951
AEG14282.1
KEGG: pth:PTH_1033 preprotein translocase subunit YajC; TIGRFAM: YajC; PFAM: YajC.
 
 
 0.942
Your Current Organism:
Desulfofundulus kuznetsovii
NCBI taxonomy Id: 760568
Other names: D. kuznetsovii DSM 6115, Desulfofundulus kuznetsovii DSM 6115, Desulfotomaculum kuznetsovii 17, Desulfotomaculum kuznetsovii DSM 6115
Server load: low (14%) [HD]