| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| bioB | bioC | ebA1066 | ebA1067 | Biotin synthase protein (EC 2.8.1.6),gene: BIOB; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | Biotin synthesis protein; Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L- methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway. | 0.915 |
| bioB | cspR | ebA1066 | ebB33 | Biotin synthase protein (EC 2.8.1.6),gene: BIOB; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | RNA methyltransferase CspR (SpoU class); Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide. | 0.602 |
| bioB | ebA1065 | ebA1066 | ebA1065 | Biotin synthase protein (EC 2.8.1.6),gene: BIOB; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | Conserved hypothetical protein,predicted phosphoribosyltransferase family. | 0.627 |
| bioB | ebA1070 | ebA1066 | ebA1070 | Biotin synthase protein (EC 2.8.1.6),gene: BIOB; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | Putative hydrolase. | 0.782 |
| bioB | ribD | ebA1066 | ebA1045 | Biotin synthase protein (EC 2.8.1.6),gene: BIOB; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.447 |
| bioC | bioB | ebA1067 | ebA1066 | Biotin synthesis protein; Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L- methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway. | Biotin synthase protein (EC 2.8.1.6),gene: BIOB; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | 0.915 |
| bioC | cspR | ebA1067 | ebB33 | Biotin synthesis protein; Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L- methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway. | RNA methyltransferase CspR (SpoU class); Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide. | 0.611 |
| bioC | ebA1065 | ebA1067 | ebA1065 | Biotin synthesis protein; Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L- methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway. | Conserved hypothetical protein,predicted phosphoribosyltransferase family. | 0.620 |
| bioC | ebA1070 | ebA1067 | ebA1070 | Biotin synthesis protein; Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L- methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway. | Putative hydrolase. | 0.783 |
| cspR | bioB | ebB33 | ebA1066 | RNA methyltransferase CspR (SpoU class); Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide. | Biotin synthase protein (EC 2.8.1.6),gene: BIOB; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | 0.602 |
| cspR | bioC | ebB33 | ebA1067 | RNA methyltransferase CspR (SpoU class); Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide. | Biotin synthesis protein; Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L- methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway. | 0.611 |
| cspR | ebA1065 | ebB33 | ebA1065 | RNA methyltransferase CspR (SpoU class); Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide. | Conserved hypothetical protein,predicted phosphoribosyltransferase family. | 0.796 |
| cspR | ebA1070 | ebB33 | ebA1070 | RNA methyltransferase CspR (SpoU class); Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide. | Putative hydrolase. | 0.577 |
| ebA1065 | bioB | ebA1065 | ebA1066 | Conserved hypothetical protein,predicted phosphoribosyltransferase family. | Biotin synthase protein (EC 2.8.1.6),gene: BIOB; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | 0.627 |
| ebA1065 | bioC | ebA1065 | ebA1067 | Conserved hypothetical protein,predicted phosphoribosyltransferase family. | Biotin synthesis protein; Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L- methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway. | 0.620 |
| ebA1065 | cspR | ebA1065 | ebB33 | Conserved hypothetical protein,predicted phosphoribosyltransferase family. | RNA methyltransferase CspR (SpoU class); Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide. | 0.796 |
| ebA1065 | ebA1070 | ebA1065 | ebA1070 | Conserved hypothetical protein,predicted phosphoribosyltransferase family. | Putative hydrolase. | 0.575 |
| ebA1070 | bioB | ebA1070 | ebA1066 | Putative hydrolase. | Biotin synthase protein (EC 2.8.1.6),gene: BIOB; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | 0.782 |
| ebA1070 | bioC | ebA1070 | ebA1067 | Putative hydrolase. | Biotin synthesis protein; Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L- methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway. | 0.783 |
| ebA1070 | cspR | ebA1070 | ebB33 | Putative hydrolase. | RNA methyltransferase CspR (SpoU class); Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide. | 0.577 |