node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ddlB | ftsI | ebA1442 | ebA1451 | D-alanine--D-alanine ligase; Cell wall formation. | Penicillin-binding 3 precursor PBP-3 transmembrane protein; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum. | 0.955 |
ddlB | ftsW | ebA1442 | ebA1445 | D-alanine--D-alanine ligase; Cell wall formation. | Cell division protein FtsW; Peptidoglycan polymerase that is essential for cell division. Belongs to the SEDS family. FtsW subfamily. | 0.961 |
ddlB | mraY | ebA1442 | ebA1448 | D-alanine--D-alanine ligase; Cell wall formation. | MraY; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | 0.957 |
ddlB | murC | ebA1442 | ebA1443 | D-alanine--D-alanine ligase; Cell wall formation. | UDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.997 |
ddlB | murD | ebA1442 | ebA1447 | D-alanine--D-alanine ligase; Cell wall formation. | UDP-N-acetylmuramoylalanine-D-glutamate ligase (EC 6.3.2.9), gene: MURD OR NE0989; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.980 |
ddlB | murE | ebA1442 | ebA1450 | D-alanine--D-alanine ligase; Cell wall formation. | UDP-N-acetylmuramoylalanyl-D-glutamate-2, 6-diamino-pimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.958 |
ddlB | murF | ebA1442 | ebA1449 | D-alanine--D-alanine ligase; Cell wall formation. | UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate--D-alanyl-D-alanyl ligase protein; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.998 |
ddlB | murG | ebA1442 | ebA1444 | D-alanine--D-alanine ligase; Cell wall formation. | Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.984 |
ebA608 | mraY | ebA608 | ebA1448 | Conserved hypothetical protein. | MraY; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | 0.908 |
ebA608 | upk | ebA608 | ebA1726 | Conserved hypothetical protein. | Putative undecaprenol kinase; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family. | 0.921 |
ftsI | ddlB | ebA1451 | ebA1442 | Penicillin-binding 3 precursor PBP-3 transmembrane protein; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum. | D-alanine--D-alanine ligase; Cell wall formation. | 0.955 |
ftsI | ftsW | ebA1451 | ebA1445 | Penicillin-binding 3 precursor PBP-3 transmembrane protein; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum. | Cell division protein FtsW; Peptidoglycan polymerase that is essential for cell division. Belongs to the SEDS family. FtsW subfamily. | 0.992 |
ftsI | mraY | ebA1451 | ebA1448 | Penicillin-binding 3 precursor PBP-3 transmembrane protein; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum. | MraY; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | 0.947 |
ftsI | murC | ebA1451 | ebA1443 | Penicillin-binding 3 precursor PBP-3 transmembrane protein; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum. | UDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.963 |
ftsI | murD | ebA1451 | ebA1447 | Penicillin-binding 3 precursor PBP-3 transmembrane protein; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum. | UDP-N-acetylmuramoylalanine-D-glutamate ligase (EC 6.3.2.9), gene: MURD OR NE0989; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.965 |
ftsI | murE | ebA1451 | ebA1450 | Penicillin-binding 3 precursor PBP-3 transmembrane protein; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum. | UDP-N-acetylmuramoylalanyl-D-glutamate-2, 6-diamino-pimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.988 |
ftsI | murF | ebA1451 | ebA1449 | Penicillin-binding 3 precursor PBP-3 transmembrane protein; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum. | UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate--D-alanyl-D-alanyl ligase protein; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.957 |
ftsI | murG | ebA1451 | ebA1444 | Penicillin-binding 3 precursor PBP-3 transmembrane protein; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum. | Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.949 |
ftsW | ddlB | ebA1445 | ebA1442 | Cell division protein FtsW; Peptidoglycan polymerase that is essential for cell division. Belongs to the SEDS family. FtsW subfamily. | D-alanine--D-alanine ligase; Cell wall formation. | 0.961 |
ftsW | ftsI | ebA1445 | ebA1451 | Cell division protein FtsW; Peptidoglycan polymerase that is essential for cell division. Belongs to the SEDS family. FtsW subfamily. | Penicillin-binding 3 precursor PBP-3 transmembrane protein; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum. | 0.992 |